{ "concept_id": 3219, "concept_version_id": 10163, "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "name": "Mixed Depression and Anxiety - Read Codes", "description": "The current concept refers to a clinician record of mixed depression and anxiety. They can be used to identify depression or anxiety in conjunction with the core diagnoses (see links to main depression/anxiety concepts). However, if a coding hierarchy is to be employed based on that used by clinicians, mixed depression and anxiety would be preferentially allocated to identify depression. \r\nThis is a sub-concept of the Datamind Collections Depression and Anxiety Phenotypes. \r\nFor full descriptions please refer to

Depression Phenontype \r\n

Anxiety Phenotype", "author": "John, A., McGregor, J., Fone, D., Dunstan, F., Cornish, R., Lyons, R. A., & Lloyd, K. R.", "entry_date": "2022-11-01", "validation_performed": true, "validation_description": "

We have developed and externally validated an algorithm for detecting cases of anxiety and depression from routine GP data using Read Codes, incoprerating symptom codes to refelct GP coding behaviour. The Read Code lists that work in combination in this algorithm have been developed based on validated published and comparable lists [John et. el. 2016; Cornish et al 2016; John et. al., 2022] and reviewed by a clinician in the study team (Prof Ann John). This algorithm was externally validated utilising the MHI-5 as the gold standard demonstrating high specificity and PPV.

", "publication_doi": "https://doi.org/10.1186/s12911-016-0274-7", "publication_link": "https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-016-0274-7", "secondary_publication_links": "

Cornish, R. P., John, A., Boyd, A., Tilling, K., & Macleod, J. (2016). Defining adolescent common mental disorders using electronic primary care data: A comparison with outcomes measured using the CIS-R. BMJ Open, 6(12).

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John, A., Marchant, A. L., Fone, D. L., McGregor, J. I., Dennis, M. S., Tan, J. O. A., & Lloyd, K. (2016). Recent trends in primary-care antidepressant prescribing to children and young people: an e-cohort study. Psychological Medicine, 46(16), 3315–3327. https://doi.org/10.1017/S0033291716002099 

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John, A., Marchant, A. L., McGregor, J. I., Tan, J. O. A., Hutchings, H. A., Kovess, V., ... & Lloyd, K. (2015). Recent trends in the incidence of anxiety and prescription of anxiolytics and hypnotics in children and young people: an e-cohort study. Journal of affective disorders, 183, 134-141.

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John, A., McGregor, J., Fone, D., Dunstan, F., Cornish, R., Lyons, R. A., & Lloyd, K. R. (2016). Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data. BMC medical informatics and decision making, 16(1), 1-10.

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John A, Friedmann Y, DelPozo-Banos M, Frizzati A, Ford T, Thapar A. Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK. Lancet Psychiatry. 2022 Jan;9(1):23-34. doi: 10.1016/S2215-0366(21)00367-9

", "paper_published": true, "source_reference": "John, A., McGregor, J., Fone, D., Dunstan, F., Cornish, R., Lyons, R. A., & Lloyd, K. R. (2016). Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data. BMC medical infor", "citation_requirements": "John, A., McGregor, J., Fone, D., Dunstan, F., Cornish, R., Lyons, R. A., & Lloyd, K. R. (2016). Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data. BMC medical infor", "owner_access": 3, "group_access": 3, "world_access": 2, "tags": [], "collections": [ { "name": "Adolescent Data Platform (ADP)", "value": 23, "type": 2 }, { "name": "DATAMIND", "value": 27, "type": 2 }, { "name": "Phenotype Library", "value": 18, "type": 2 } ], "created_by": null, "modified_by": null, "owner": null, "group": null, "phenotype_owner": "PH1113", "phenotype_owner_history_id": 3471, "requested_entity_id": null, "components": [ { "id": 3842, "name": "Mixed depression and anxiety - Read Codes", "logical_type": "INCLUDE", "source_type": "SELECT_IMPORT", "source": null, "codes": [ { "id": 252904, "code": "E2003", "description": "Anxiety with depression" }, { "id": 252905, "code": "Eu412", "description": "[X]Mixed anxiety and depressive disorder" } ] } ], "version_history": [ { "version_id": 10163, "version_name": "Mixed Depression and Anxiety - Read Codes", "version_date": "2023-02-07T07:33:26.341073Z", "is_published": true, "is_latest": true }, { "version_id": 9536, "version_name": "Mixed Depression and Anxiety - Read Codes", "version_date": "2023-01-10T08:00:57.495592Z", "is_published": true, "is_latest": false }, { "version_id": 9532, "version_name": "Mixed Depression and Anxiety - Read Codes", "version_date": "2023-01-10T07:57:54.455498Z", "is_published": false, "is_latest": false }, { "version_id": 9444, "version_name": "Mixed Depression and Anxiety - Read Codes", "version_date": "2023-01-09T08:12:36.496375Z", "is_published": false, "is_latest": false }, { "version_id": 9384, "version_name": "Mixed Anxiety and Depression - Primary Care", "version_date": "2023-01-03T10:36:15.406744Z", "is_published": false, "is_latest": false }, { "version_id": 8772, "version_name": "Mixed Anxiety and Depression - Primary Care", "version_date": "2022-11-01T08:24:12.455799Z", "is_published": true, "is_latest": false }, { "version_id": 8771, "version_name": "Mixed Anxiety and Depression - Primary Care", "version_date": "2022-11-01T08:24:04.887380Z", "is_published": false, "is_latest": false }, { "version_id": 8770, "version_name": "Mixed Anxiety and Depression - Primary Care", "version_date": "2022-11-01T08:19:50.534296Z", "is_published": false, "is_latest": false } ] }