{
  "id": 2720,
  "label": "polymicrogyria",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000087",
  "properties": {
    "xrefs": [
      "DOID:0080918",
      "GARD:0018818",
      "MEDGEN:78605",
      "MESH:D065706",
      "NANDO:1201071",
      "NCIT:C116936",
      "Orphanet:35981",
      "SCTID:4945003",
      "UMLS:C0266464",
      "icd11.foundation:2081858551"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A developmental brain abnormality characterized by an excessive amount of small convolutions on the surface of the brain and cognitive dysfunction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4427,
      "label": "congenital nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2490",
          "ICD9:742",
          "MEDGEN:105425",
          "NCIT:C97172",
          "UMLS:C0497552"
        ],
        "synonyms": [
          "congenital abnormality of the nervous system",
          "congenital nervous system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An abnormality of the nervous system that is present at birth or detected in the neonatal period."
      },
      "child_count": 217,
      "reference_id": "MONDO:0002320"
    }
  ],
  "children": [
    {
      "id": 17468,
      "label": "bilateral polymicrogyria",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017269",
          "MEDGEN:1647593",
          "Orphanet:268940",
          "SCTID:765757003",
          "UMLS:C4707565",
          "icd11.foundation:422828750"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Bilateral polymicrogyria is a rare cerebral malformation due to abnormal neuronal migration defined as a cerebral cortex with many excessively small convolutions. It presents with developmental delay, intellectual disability, seizures and various neurological impairments and may be isolated or comprise a clinical feature of many genetic syndromes. It may also be associated with perinatal cytomegalovirus infection."
      },
      "child_count": 5,
      "reference_id": "MONDO:0017091"
    },
    {
      "id": 17469,
      "label": "unilateral polymicrogyria",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020980",
          "MEDGEN:870513",
          "Orphanet:268943",
          "SCTID:715905006",
          "UMLS:C4024960",
          "icd11.foundation:782302128"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Unilateral polymicrogyria is a cerebral cortical malformation characterized by unilateral excessive cortical folding and abnormal cortical layering. It comprises two sub-types depending on the areas affected: unilateral hemispheric and focal polymicrogyria."
      },
      "child_count": 2,
      "reference_id": "MONDO:0017092"
    }
  ],
  "roots": [
    {
      "id": 4427,
      "label": "congenital nervous system disorder"
    }
  ]
}