{
  "id": 2723,
  "label": "anemia, hypochromic microcytic with iron overload",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000104",
  "properties": {
    "xrefs": [
      "GARD:0022710",
      "MEDGEN:388759",
      "MESH:C567144",
      "OMIMPS:206100",
      "UMLS:C2673913"
    ],
    "synonyms": [
      "anemia, hypochromic microcytic, with iron overload"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 2886,
      "label": "hypochromic microcytic anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3485,
        3581
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050642",
          "HP:0004840",
          "MEDGEN:124413",
          "MESH:C536357",
          "SCTID:44666001",
          "UMLS:C0271901"
        ],
        "synonyms": [
          "hypochromic microcytic anaemia (disease)",
          "hypochromic microcytic anemia",
          "hypochromic microcytic anemia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Anemia in which the circulating RBCs are smaller than the usual size of RBCs (microcytic) and have decreased red color (hypochromic)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0000387"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    }
  ],
  "children": [
    {
      "id": 10058,
      "label": "microcytic anemia with liver iron overload",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2723,
        17107,
        17988
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012360",
          "MEDGEN:812483",
          "OMIM:206100",
          "Orphanet:83642",
          "SCTID:711161006",
          "UMLS:C3806153"
        ],
        "synonyms": [
          "anemia, hypochromic microcytic, with iron overload type 1",
          "AHMIO1",
          "anemia, hypochromic microcytic, with iron overload 1",
          "hypochromic microcytic anaemia with iron overload",
          "hypochromic microcytic anemia with iron overload",
          "microcytic anaemia and hepatic iron overload",
          "microcytic anemia and hepatic iron overload"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital hypochromic microcytic anemia with progressive liver iron overload paradoxically associated with normal to moderately elevated serum ferritin levels has been described in three unrelated patients."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008787"
    },
    {
      "id": 15103,
      "label": "severe congenital hypochromic anemia with ringed sideroblasts",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2723,
        3000,
        17107,
        19734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017364",
          "MEDGEN:815250",
          "OMIM:615234",
          "Orphanet:300298",
          "SCTID:725463007",
          "UMLS:C3808920"
        ],
        "synonyms": [
          "anemia, hypochromic microcytic, with iron overload type 2",
          "severe congenital hypochromic sideroblastic anaemia",
          "severe congenital hypochromic sideroblastic anemia",
          "AHMIO2",
          "anemia, hypochromic microcytic, with iron overload 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "STEAP3/TSAP6-related sideroblastic anemia is a very rare severe non-syndromic hypochromic anemia, which is characterized by transfusion-dependent hypochromic, poorly regenerative anemia, iron overload, resembling non-syndromic sideroblastic anemia except for increased erythrocyte protoporphyrin levels."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014094"
    }
  ],
  "roots": [
    {
      "id": 2886,
      "label": "hypochromic microcytic anemia"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    }
  ]
}