{
  "id": 2727,
  "label": "bifid nose",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000110",
  "properties": {
    "xrefs": [
      "GARD:0000884",
      "MEDGEN:66379",
      "MESH:C535441",
      "Orphanet:2695",
      "UMLS:C0221363",
      "icd11.foundation:1824850646"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "Bifid nose is a rare congenital malformation of presumed autosomal dominant or recessive inheritance characterized by clefting of the nose ranging from a minimally noticeable groove in the columella to complete clefting of the underlying bones and cartilage (resulting in two half noses) with a usually adequate airway. Bifid nose may be seen in frontonasal dysplasia while other malformations such as hypertelorbitism and midline clefts of the lip may also be associated."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 16263,
      "label": "facial cleft",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19507,
        21213
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019964",
          "MEDGEN:146898",
          "NCIT:C124510",
          "Orphanet:141229",
          "SCTID:92821006",
          "UMLS:C0685787",
          "icd11.foundation:11389088"
        ],
        "synonyms": [
          "cleft face",
          "craniofacial cleft",
          "prosoposchisis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A congenital abnormality consisting of an opening or gap in the face, which results from incomplete fusion of one or more of the embryonic facial prominences."
      },
      "child_count": 18,
      "reference_id": "MONDO:0015411"
    },
    {
      "id": 21538,
      "label": "otorhinolaryngologic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:478.19",
          "MEDGEN:583054",
          "MESH:D010038",
          "NANDO:1100015",
          "NCIT:C118420",
          "SCTID:232208008",
          "UMLS:C0395797"
        ],
        "synonyms": [
          "ear, nose and throat disorder",
          "ear, nose or throat disorder",
          "ear/nose/throat disease",
          "otolaryngologic disorder",
          "otorhinolaryngologic disease",
          "ENT disease",
          "ENT diseases",
          "disease, ENT",
          "disease, otolaryngologic",
          "disease, otolaryngological",
          "disease, otorhinolaryngologic",
          "disease, otorhinolaryngological",
          "diseases, ENT",
          "diseases, otolaryngologic",
          "diseases, otolaryngological",
          "diseases, otorhinolaryngologic",
          "diseases, otorhinolaryngological",
          "otolaryngologic disease",
          "otolaryngologic diseases",
          "otolaryngological disease",
          "otolaryngological diseases",
          "otorhinolaryngological disease",
          "otorhinolaryngological diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases."
      },
      "child_count": 40,
      "reference_id": "MONDO:0024623"
    }
  ],
  "children": [
    {
      "id": 8601,
      "label": "bifid nose, autosomal dominant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015044",
          "MEDGEN:414016",
          "OMIM:109740",
          "UMLS:C2751431"
        ],
        "synonyms": [
          "bifid nose, autosomal dominant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0007195"
    },
    {
      "id": 10131,
      "label": "bifid nose, autosomal recessive",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2727,
        7611,
        18718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015142",
          "MEDGEN:854359",
          "OMIM:210400",
          "UMLS:C3887497"
        ],
        "synonyms": [
          "autosomal recessive bifid nose",
          "bifid nose, autosomal recessive",
          "Nose, Median cleft of",
          "median fissure of Nose"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Autosomal recessive form of bifid nose."
      },
      "child_count": 3,
      "reference_id": "MONDO:0008866"
    },
    {
      "id": 13228,
      "label": "BNAR syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2727,
        4370,
        16089,
        18718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010595",
          "MEDGEN:413305",
          "MESH:C567672",
          "OMIM:608980",
          "Orphanet:217266",
          "SCTID:717940006",
          "UMLS:C2750433"
        ],
        "synonyms": [
          "bifid nose with or without anorectal and renal anomalies",
          "BNAR",
          "bifid NOSE with or without anorectal and renal anomalies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "BNAR syndrome is a very rare multiple congenital anomaly syndrome characterized by a bifid nose (with bulbous nasal tip but not associated with hypertelorism) with or without the presence of anal defects (i.e. anteriorly placed anus, rectal stenosis or atresia) and renal dysplasia (unilateral or bilateral renal agenesis) and without intellectual disability. BNAR syndrome is phenotypically related to Fraser syndrome and oculotrichoanal syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012165"
    }
  ],
  "roots": [
    {
      "id": 16263,
      "label": "facial cleft"
    },
    {
      "id": 21538,
      "label": "otorhinolaryngologic disease"
    }
  ]
}