{
  "id": 2731,
  "label": "reticulate pigment disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000118",
  "properties": {
    "xrefs": [
      "GARD:0022712",
      "OMIMPS:179850"
    ],
    "synonyms": [
      "reticulate pigment disorders"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19139,
      "label": "skin pigmentation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10123",
          "ICD9:709.09",
          "MEDGEN:316465",
          "MESH:D010859",
          "NCIT:C34557",
          "Orphanet:79374",
          "UMLS:C1704421"
        ],
        "synonyms": [
          "pigmentation anomaly of the skin",
          "pigmentation disease of zone of skin",
          "zone of skin pigmentation disease",
          "pigmentation disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A pigmentation disease that involves the zone of skin."
      },
      "child_count": 4,
      "reference_id": "MONDO:0019288"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D012873",
          "SCTID:239001006"
        ],
        "synonyms": [
          "disease, genetic skin",
          "diseases, genetic skin",
          "genetic skin disease",
          "genetic skin diseases",
          "genodermatosis",
          "skin disease, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of skin disease that is caused by a modification of the individual's genome."
      },
      "child_count": 228,
      "reference_id": "MONDO:0100118"
    }
  ],
  "children": [
    {
      "id": 8870,
      "label": "dyschromatosis symmetrica hereditaria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2731,
        19140,
        24656
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060257",
          "GARD:0000334",
          "MEDGEN:96071",
          "MESH:C535729",
          "NCIT:C118435",
          "OMIM:127400",
          "Orphanet:41",
          "SCTID:239085000",
          "UMLS:C0406775"
        ],
        "synonyms": [
          "DSH1",
          "RAD",
          "acropigmentation of Dohi",
          "dyschromatosis symmetrica hereditaria",
          "reticulate acropigmentation of Dohi",
          "DSH",
          "dyschromatosis symmetrica hereditaria 1",
          "familial reticulate acropigmentation of Dohi",
          "symmetric dyschromatosis of the extremities"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Acropigmentation of Dohi is a genodermatosis characterized by the presence of hyperpigmented and hypopigmented macules, principally located on the extremities and limbs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007483"
    },
    {
      "id": 9670,
      "label": "Dowling-Degos disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2731,
        17976,
        19140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060256",
          "GARD:0009775",
          "MEDGEN:811363",
          "MESH:C562924",
          "MedDRA:10068651",
          "Orphanet:79145",
          "UMLS:C3714534",
          "icd11.foundation:15123132"
        ],
        "synonyms": [
          "Dowling-Degos disease type 1",
          "reticular pigment anomaly of flexures",
          "DDD1",
          "Dowling-Degos Kitamura disease",
          "Dowling-Degos disease 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A pigmentation disease characterized by a reticulate pattern of abnormally dark skin coloring, particularly in the body's folds and creases."
      },
      "child_count": 12,
      "reference_id": "MONDO:0008371"
    },
    {
      "id": 15240,
      "label": "reticulate acropigmentation of Kitamura",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2731,
        19140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060258",
          "GARD:0017079",
          "ICD9:709.09",
          "MEDGEN:98363",
          "OMIM:615537",
          "Orphanet:178307",
          "SCTID:239133004",
          "UMLS:C0406811"
        ],
        "synonyms": [
          "reticulate acropigmentation of Kitamura",
          "Kitamura reticulate acropigmentation",
          "RAK",
          "acropigmentatio reticularis",
          "reticulate pigmentation of Kitamura"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A pigmentation disease characterized by lesions that initially arise as letiginous, hyperpigmented macules in a reticular pattern on the dorsal aspect of the hands and feet. Over time, lesions may spread proximally and may darken; palmoplantar pitting and dermatoglyphic disruption may also be present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014234"
    }
  ],
  "roots": [
    {
      "id": 19139,
      "label": "skin pigmentation disorder"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder"
    }
  ]
}