{
  "id": 2743,
  "label": "pulmonary fibrosis and/or bone marrow failure, telomere-related",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000148",
  "properties": {
    "xrefs": [
      "GARD:0022715",
      "OMIMPS:614742"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 4804,
      "label": "pulmonary fibrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16615
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3770",
          "EFO:0009448",
          "GARD:0023241",
          "MEDGEN:11028",
          "MESH:D011658",
          "NCIT:C26869",
          "SCTID:51615001",
          "UMLS:C0034069"
        ],
        "synonyms": [
          "pulmonary interstitial fibrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Chronic progressive interstitial lung disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure, or right heart failure. Causes include chronic inflammatory processes, exposure to environmental irritants, radiation therapy, autoimmune disorders, certain drugs, or it may be idiopathic (no identifiable cause)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002771"
    },
    {
      "id": 22225,
      "label": "inherited interstitial lung disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        16615
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027936",
          "OMIMPS:619611"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An instance of interstitial lung disease that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 26,
      "reference_id": "MONDO:0031199"
    },
    {
      "id": 23885,
      "label": "telomere syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19146
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026060",
          "MEDGEN:1668986",
          "NCIT:C152065",
          "UMLS:C4727832"
        ],
        "synonyms": [
          "STS",
          "short telomere syndrome"
        ],
        "definition": "Accelerated aging syndromes often caused by inheritable gene mutations resulting in decreased telomere lengths."
      },
      "child_count": 7,
      "reference_id": "MONDO:0100137"
    }
  ],
  "children": [
    {
      "id": 14890,
      "label": "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001501",
          "GARD:0024959",
          "MEDGEN:766531",
          "OMIM:614742",
          "UMLS:C3553617"
        ],
        "synonyms": [
          "TERT pulmonary fibrosis and/or bone marrow failure, Telomere-related",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related caused by mutation in TERT",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 1",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, type 1",
          "PFBMFT1",
          "pulmonary fibrosis and/or bone marrow failure, TELOMERE-RELATED, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Any pulmonary fibrosis and/or bone marrow failure, Telomere-related in which the cause of the disease is a mutation in the TERT gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013878"
    },
    {
      "id": 14891,
      "label": "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024960",
          "MEDGEN:766536",
          "OMIM:614743",
          "UMLS:C3553622"
        ],
        "synonyms": [
          "aplastic anaemia",
          "aplastic anemia",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 2",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, type 2",
          "PFBMFT2",
          "pulmonary fibrosis and/or bone marrow failure, TELOMERE-RELATED, 2",
          "pulmonary fibrosis, idiopathic, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0013879"
    },
    {
      "id": 15609,
      "label": "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016097",
          "MEDGEN:903928",
          "OMIM:616371",
          "UMLS:C4225347"
        ],
        "synonyms": [
          "PARN pulmonary fibrosis and/or bone marrow failure, Telomere-related",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related caused by mutation in PARN",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 4",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, type 4",
          "PFBMFT4",
          "pulmonary fibrosis and/or bone marrow failure, TELOMERE-RELATED, 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Any pulmonary fibrosis and/or bone marrow failure, Telomere-related in which the cause of the disease is a mutation in the PARN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014612"
    },
    {
      "id": 15610,
      "label": "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743,
        25053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016098",
          "MEDGEN:901644",
          "OMIM:616373",
          "UMLS:C4225346"
        ],
        "synonyms": [
          "RTEL1 pulmonary fibrosis and/or bone marrow failure, Telomere-related",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related caused by mutation in RTEL1",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, 3",
          "pulmonary fibrosis and/or bone marrow failure, Telomere-related, type 3",
          "PFBMFT3",
          "pulmonary fibrosis and/or bone marrow failure, TELOMERE-RELATED, 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Any pulmonary fibrosis and/or bone marrow failure, Telomere-related in which the cause of the disease is a mutation in the RTEL1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014613"
    },
    {
      "id": 22001,
      "label": "pulmonary fibrosis and/or bone marrow failure, telomere-related, 6",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025613",
          "MEDGEN:1805650",
          "OMIM:619767",
          "UMLS:C5676927"
        ],
        "synonyms": [
          "PFBMFT6",
          "pulmonary fibrosis and/or bone marrow failure, telomere-related, 6"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0030690"
    },
    {
      "id": 22517,
      "label": "pulmonary fibrosis and/or bone marrow failure, telomere-related, 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025762",
          "MEDGEN:1684878",
          "OMIM:618674",
          "UMLS:C5231457"
        ],
        "synonyms": [
          "ZCCHC8-related telomere biology disorder",
          "PFBMFT5",
          "PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0032865"
    },
    {
      "id": 25629,
      "label": "pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026800",
          "MEDGEN:1841121",
          "OMIM:620365",
          "UMLS:C5830485"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0957261"
    },
    {
      "id": 25631,
      "label": "pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026802",
          "MEDGEN:1841132",
          "OMIM:620367",
          "UMLS:C5830496"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0957263"
    },
    {
      "id": 25646,
      "label": "pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2743
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026813",
          "MEDGEN:1841196",
          "OMIM:620400",
          "UMLS:C5830560"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0957294"
    }
  ],
  "roots": [
    {
      "id": 4804,
      "label": "pulmonary fibrosis"
    },
    {
      "id": 22225,
      "label": "inherited interstitial lung disease"
    },
    {
      "id": 23885,
      "label": "telomere syndrome"
    }
  ]
}