{
  "id": 2808,
  "label": "pulmonary aspergilloma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000266",
  "properties": {
    "xrefs": [
      "DOID:0050153",
      "EFO:1001834",
      "GARD:0022738",
      "MEDGEN:390019",
      "MESH:D055732",
      "UMLS:C2350529"
    ],
    "synonyms": [
      "lung aspergillosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A aspergillosis that involves the lung."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7292,
      "label": "aspergillosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4420
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:1988-4002",
          "DOID:13564",
          "EFO:0007157",
          "GARD:0005856",
          "ICD10CM:B44",
          "ICD10WHO:B44",
          "ICD9:117.3",
          "MEDGEN:13939",
          "MESH:D001228",
          "MedDRA:10003488",
          "NCIT:C2886",
          "NORD:814",
          "Orphanet:1163",
          "SCTID:65553006",
          "UMLS:C0004030",
          "icd11.foundation:1913468488"
        ],
        "definition": "Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005657"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007278",
          "MEDGEN:6144",
          "MESH:D008172",
          "UMLS:C0024116"
        ],
        "synonyms": [
          "Fungi caused lung disease",
          "Fungi lung disease",
          "fungal disease, pulmonary",
          "fungal diseases, pulmonary",
          "fungal infection, pulmonary",
          "fungal infections, pulmonary",
          "fungal lung disease",
          "fungal lung diseases",
          "lung disease, fungal",
          "pulmonary fungal disease",
          "pulmonary fungal diseases",
          "pulmonary fungal infection",
          "pulmonary fungal infections"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pulmonary diseases caused by fungal infections, usually through hematogenous spread."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005766"
    }
  ],
  "children": [
    {
      "id": 2787,
      "label": "invasive aspergillosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2808
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050073",
          "GARD:0022735",
          "MEDGEN:922866",
          "SCTID:721798004",
          "UMLS:C0238013",
          "icd11.foundation:1314810340"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000240"
    },
    {
      "id": 4381,
      "label": "malt worker's lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2808,
        16132,
        18069,
        20956
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2314",
          "GARD:0023103",
          "ICD9:495.4",
          "MEDGEN:510125",
          "SCTID:25897000",
          "UMLS:C0155888"
        ],
        "synonyms": [
          "Aspergillus caused extrinsic allergic alveolitis",
          "Aspergillus extrinsic allergic alveolitis",
          "Malt workers' lung",
          "malt workers lung",
          "alveolitis due to aspergillus clavatus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An extrinsic allergic alveolitis caused by infection with Aspergillus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002266"
    }
  ],
  "roots": [
    {
      "id": 7292,
      "label": "aspergillosis"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease"
    }
  ]
}