{
  "id": 2875,
  "label": "respiratory system cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000376",
  "properties": {
    "xrefs": [
      "DOID:0050615",
      "ICD10CM:C34",
      "ICD9:165.8",
      "ICD9:165.9",
      "MEDGEN:756863",
      "NCIT:C4571",
      "SCTID:449096009",
      "UMLS:C3164456",
      "icd11.foundation:401100796"
    ],
    "synonyms": [
      "cancer of respiratory system",
      "malignant neoplasm of respiratory system",
      "malignant respiratory system neoplasm",
      "respiratory system cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the respiratory system"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
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          "ICD9:199",
          "ICD9:199.1",
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          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
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          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    },
    {
      "id": 6815,
      "label": "respiratory system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
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      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1579",
          "EFO:0000684",
          "ICD10CM:J00-J99",
          "ICD9:460-519",
          "ICD9:500-508",
          "ICD9:503",
          "ICD9:508",
          "ICD9:508.1",
          "ICD9:508.8",
          "ICD9:508.9",
          "ICD9:510-519",
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          "ICD9:516.8",
          "ICD9:516.9",
          "ICD9:517",
          "ICD9:517.8",
          "ICD9:519",
          "ICD9:519.1",
          "ICD9:519.3",
          "ICD9:519.8",
          "ICD9:519.9",
          "ICD9:V12.60",
          "ICD9:V47.2",
          "MEDGEN:48421",
          "MESH:D012140",
          "NANDO:1100010",
          "NCIT:C26871",
          "SCTID:50043002",
          "UMLS:C0035204"
        ],
        "synonyms": [
          "disease of respiratory system",
          "disease or disorder of respiratory system",
          "disorder of respiratory system",
          "respiratory disease",
          "respiratory disorder",
          "respiratory system disease",
          "respiratory system disease or disorder",
          "respiratory system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma."
      },
      "child_count": 59,
      "reference_id": "MONDO:0005087"
    }
  ],
  "children": [
    {
      "id": 3375,
      "label": "nasal cavity cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        3050,
        6527,
        7266
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10811",
          "ICD10CM:C30.0",
          "ICD9:160.0",
          "MEDGEN:152601",
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          "SCTID:363422006",
          "UMLS:C0728864",
          "icd11.foundation:1078206702"
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        "synonyms": [
          "cancer of nasal cavity",
          "malignant nasal cavity neoplasm",
          "malignant nasal cavity tumor",
          "malignant nasal cavity tumour",
          "malignant neoplasm of nasal cavities",
          "malignant neoplasm of nasal cavity",
          "malignant neoplasm of the nasal cavity",
          "malignant tumor of nasal cavity",
          "malignant tumor of the nasal cavity",
          "malignant tumour of nasal cavity",
          "malignant tumour of the nasal cavity",
          "nasal cavity cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A malignant neoplasm involving the nasal cavity"
      },
      "child_count": 12,
      "reference_id": "MONDO:0001128"
    },
    {
      "id": 3628,
      "label": "tracheal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        20428
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11920",
          "ICD10CM:C33",
          "ICD9:162.0",
          "MEDGEN:102274",
          "NCIT:C9346",
          "SCTID:363432004",
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          "icd11.foundation:1630573405"
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        "synonyms": [
          "tracheal neoplasm",
          "Ca trachea",
          "cancer of trachea",
          "malignant neoplasm of the trachea",
          "malignant neoplasm of trachea",
          "malignant trachea neoplasm",
          "malignant trachea tumor",
          "malignant trachea tumour",
          "malignant tracheal neoplasm",
          "malignant tracheal tumor",
          "malignant tracheal tumour",
          "malignant tumor of the trachea",
          "malignant tumor of trachea",
          "malignant tumour of the trachea",
          "malignant tumour of trachea",
          "trachea cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the trachea"
      },
      "child_count": 6,
      "reference_id": "MONDO:0001407"
    },
    {
      "id": 3865,
      "label": "bronchus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        4833
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1325",
          "ICD9:162.8",
          "ICD9:162.9",
          "MEDGEN:730206",
          "NCIT:C156885",
          "SCTID:363493006",
          "UMLS:C1322284",
          "icd11.foundation:1501594633"
        ],
        "synonyms": [
          "bronchus cancer",
          "cancer of bronchus",
          "malignant bronchus neoplasm",
          "malignant neoplasm of bronchus",
          "malignant neoplasm of bronchus and lung",
          "malignant neoplasm of bronchus and lung, unspecified",
          "malignant neoplasm of bronchus or lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the bronchus"
      },
      "child_count": 4,
      "reference_id": "MONDO:0001672"
    },
    {
      "id": 4451,
      "label": "larynx cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        20312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2596",
          "EFO:1000354",
          "GARD:0027604",
          "ICD10CM:C32",
          "ICD9:161",
          "ICD9:161.8",
          "ICD9:161.9",
          "MEDGEN:2868",
          "NCIT:C7484",
          "SCTID:363429002",
          "UMLS:C0007107",
          "icd11.foundation:75194057"
        ],
        "synonyms": [
          "cancer of larynx",
          "larynx cancer",
          "malignant laryngeal neoplasm",
          "malignant laryngeal tumor",
          "malignant laryngeal tumour",
          "malignant larynx neoplasm",
          "malignant larynx tumor",
          "malignant larynx tumour",
          "malignant neoplasm of larynx",
          "malignant neoplasm of the larynx",
          "malignant tumor of larynx",
          "malignant tumor of the larynx",
          "malignant tumour of larynx",
          "malignant tumour of the larynx"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the larynx. The majority are carcinomas."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002352"
    },
    {
      "id": 7172,
      "label": "pharynx cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        4587,
        20028,
        20455,
        20492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060119",
          "EFO:0005577",
          "MEDGEN:57554",
          "MESH:D010610",
          "NCIT:C7545",
          "UMLS:C0153405"
        ],
        "synonyms": [
          "pharynx neoplasm",
          "cancer of chordate pharynx",
          "cancer of pharynx",
          "chordate pharynx cancer",
          "malignant chordate pharynx neoplasm",
          "malignant neoplasm of chordate pharynx",
          "malignant neoplasm of pharynx",
          "malignant pharyngeal neoplasm",
          "malignant pharyngeal tumor",
          "malignant pharyngeal tumour",
          "malignant pharynx neoplasm",
          "malignant pharynx tumor",
          "malignant pharynx tumour",
          "malignant tumor of pharynx",
          "malignant tumor of the pharynx",
          "malignant tumour of pharynx",
          "malignant tumour of the pharynx",
          "pharynx cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the pharynx."
      },
      "child_count": 25,
      "reference_id": "MONDO:0005517"
    },
    {
      "id": 7835,
      "label": "pleural cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        5215,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5158",
          "EFO:1000362",
          "ICD10CM:C38.4",
          "ICD9:163",
          "ICD9:163.8",
          "ICD9:163.9",
          "MEDGEN:56307",
          "NCIT:C3547",
          "SCTID:363433009",
          "UMLS:C0153494"
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        "synonyms": [
          "neoplasm of pleura",
          "pleural tumor",
          "pleural tumour",
          "cancer of pleura",
          "cancer of the pleura",
          "malignant neoplasm of pleura",
          "malignant neoplasm of the pleura",
          "malignant pleura neoplasm",
          "malignant pleural neoplasm",
          "malignant pleural tumor",
          "malignant pleural tumour",
          "malignant tumor of pleura",
          "malignant tumor of the pleura",
          "malignant tumour of pleura",
          "malignant tumour of the pleura",
          "pleura cancer",
          "pleural cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the pleura. A representative example of primary malignant pleural neoplasm is the malignant pleural mesothelioma. A representative example of metastatic malignant neoplasm to the pleura is metastatic carcinoma that has spread to the pleura from another anatomic site."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006294"
    },
    {
      "id": 10167,
      "label": "lung cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        5215,
        20356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1324",
          "ICD9:162.3",
          "ICD9:162.4",
          "ICD9:162.5",
          "ICD9:162.8",
          "ICD9:162.9",
          "MEDGEN:66885",
          "NCIT:C7377",
          "OMIM:211980",
          "SCTID:363358000",
          "UMLS:C0242379"
        ],
        "synonyms": [
          "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
          "adenocarcinoma of lung, somatic",
          "cancer of lung",
          "lung cancer",
          "lung cancer, protection against, autosomal dominant, somatic mutation",
          "lung cancer, resistance to, autosomal dominant, somatic mutation",
          "lung cancer, somatic",
          "lung cancer, susceptibility to, autosomal dominant, somatic mutation",
          "malignant lung neoplasm",
          "malignant lung tumor",
          "malignant lung tumour",
          "malignant neoplasm of lung",
          "malignant neoplasm of the lung",
          "malignant tumor of lung",
          "malignant tumor of the lung",
          "malignant tumour of lung",
          "malignant tumour of the lung",
          "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
          "nonsmall cell lung cancer, somatic",
          "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation",
          "Nonsmall cell lung cancer",
          "alveolar cell carcinoma",
          "lung cancer, protection against"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the lung."
      },
      "child_count": 21,
      "reference_id": "MONDO:0008903"
    },
    {
      "id": 18726,
      "label": "SMARCA4-deficient sarcoma of thorax",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2875,
        18239,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080532",
          "GARD:0021943",
          "MEDGEN:1806595",
          "NCIT:C183115",
          "Orphanet:466962",
          "UMLS:C5554190"
        ],
        "synonyms": [
          "SMARCA4-deficient thoracic sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018761"
    },
    {
      "id": 20081,
      "label": "paranasal sinus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2875,
        3050,
        4265,
        6984
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025207",
          "MEDGEN:56305",
          "NCIT:C7487",
          "UMLS:C0153474"
        ],
        "synonyms": [
          "malignant accessory sinus neoplasm",
          "malignant accessory sinus tumor",
          "malignant accessory sinus tumour",
          "malignant neoplasm of accessory sinus",
          "malignant neoplasm of paranasal sinus",
          "malignant neoplasm of the accessory sinus",
          "malignant neoplasm of the paranasal sinus",
          "malignant paranasal sinus neoplasm",
          "malignant paranasal sinus tumor",
          "malignant paranasal sinus tumour",
          "malignant tumor of accessory sinus",
          "malignant tumor of paranasal sinus",
          "malignant tumor of the accessory sinus",
          "malignant tumor of the paranasal sinus",
          "malignant tumour of accessory sinus",
          "malignant tumour of paranasal sinus",
          "malignant tumour of the accessory sinus",
          "malignant tumour of the paranasal sinus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the paranasal sinuses."
      },
      "child_count": 8,
      "reference_id": "MONDO:0020669"
    }
  ],
  "roots": [
    {
      "id": 6733,
      "label": "cancer"
    },
    {
      "id": 6815,
      "label": "respiratory system disorder"
    }
  ]
}