{
  "id": 2894,
  "label": "small cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000402",
  "properties": {
    "xrefs": [
      "DOID:0050685",
      "EFO:0008524",
      "GARD:0022765",
      "ICDO:8041/3",
      "ICDO:8042/3",
      "MEDGEN:90748",
      "MESH:D018288",
      "NCIT:C3915",
      "NCIT:C4099",
      "SCTID:11010461000119101",
      "UMLS:C0334239"
    ],
    "synonyms": [
      "oat cell cancer",
      "oat cell carcinoma",
      "small cell NEC",
      "small cell cancer",
      "small cell car. (extrapulmonary)",
      "small cell carcinoma",
      "small cell carcinoma (extrapulmonary)",
      "small cell neuroendocrine carcinoma",
      "intermediate cell small cell carcinoma",
      "small cell carcinoma - intermediate cell",
      "small cell carcinoma, intermediate cell",
      "small cell carcinoma, intermediate cell (morphologic abnormality)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble \"oat cells\" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 18,
  "parents": [
    {
      "id": 4255,
      "label": "neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        19314,
        20310
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1800",
          "GARD:0023067",
          "ICDO:8246/3",
          "MEDGEN:104919",
          "MESH:D018278",
          "NCIT:C3773",
          "SCTID:253000007",
          "UMLS:C0206695"
        ],
        "synonyms": [
          "NEC",
          "neuroendocrine cancer",
          "neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma."
      },
      "child_count": 36,
      "reference_id": "MONDO:0002120"
    }
  ],
  "children": [
    {
      "id": 5590,
      "label": "extrahepatic bile duct small cell adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4714,
        16046
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5926",
          "GARD:0023628",
          "MEDGEN:277648",
          "NCIT:C5845",
          "UMLS:C1335979"
        ],
        "synonyms": [
          "Oat cell carcinoma of extrahepatic bile duct",
          "Oat cell carcinoma of the extrahepatic bile duct",
          "Oat cell extrahepatic bile duct carcinoma",
          "extrahepatic bile duct small cell NEC",
          "extrahepatic bile duct small cell neuroendocrine carcinoma",
          "small cell adenocarcinoma of extrahepatic bile duct",
          "small cell adenocarcinoma of the extrahepatic bile duct",
          "small cell extrahepatic bile duct carcinoma",
          "small cell extrahepatic bile duct neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the extrahepatic bile ducts. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003708"
    },
    {
      "id": 5672,
      "label": "ovarian small cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2894,
        4561,
        6864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6179",
          "EFO:1000431",
          "GARD:0010411",
          "MEDGEN:389177",
          "NCIT:C27390",
          "ONCOTREE:SCCO",
          "Orphanet:370396",
          "UMLS:C2212006"
        ],
        "synonyms": [
          "SCCO",
          "ovarian small cell NEC",
          "ovarian small cell cancer",
          "ovarian small cell carcinoma",
          "ovarian small cell neuroendocrine carcinoma",
          "ovary small cell carcinoma",
          "small cell carcinoma of ovary",
          "small cell carcinoma of the ovary",
          "small cell ovarian carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the ovary and is characterized by the presence of small malignant cells. It includes small cell carcinoma, hypercalcemic type and small cell carcinoma, pulmonary type."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003795"
    },
    {
      "id": 5833,
      "label": "colon small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4179,
        4895
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6727",
          "GARD:0023759",
          "MEDGEN:232087",
          "NCIT:C6761",
          "UMLS:C1333099"
        ],
        "synonyms": [
          "Oat cell carcinoma of colon",
          "Oat cell carcinoma of the colon",
          "Oat cell colon carcinoma",
          "colon Oat cell carcinoma",
          "colon small cell carcinoma",
          "colon small cell neuroendocrine cancer",
          "colon small cell neuroendocrine carcinoma",
          "colonic Oat cell carcinoma",
          "colonic small cell carcinoma",
          "small cell carcinoma of colon",
          "small cell carcinoma of the colon",
          "small cell colon carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the colon. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003978"
    },
    {
      "id": 5947,
      "label": "urinary bladder small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        6727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7132",
          "EFO:1000129",
          "GARD:0011923",
          "MEDGEN:231950",
          "NCIT:C9461",
          "ONCOTREE:SCBC",
          "Orphanet:284400",
          "UMLS:C1332564"
        ],
        "synonyms": [
          "SCCB",
          "bladder small cell neuroendocrine cancer",
          "bladder small cell neuroendocrine carcinoma",
          "poorly differentiated neuroendocrine carcinoma of the bladder",
          "small cell bladder cancer",
          "small cell bladder carcinoma",
          "small cell carcinoma of the urinary bladder",
          "small cell carcinoma of urinary bladder",
          "small cell neuroendocrine carcinoma of the urinary bladder",
          "small cell neuroendocrine carcinoma of urinary bladder",
          "urinary bladder small cell carcinoma",
          "small cell carcinoma of the bladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A highly aggressive carcinoma, histologically resembling small cell lung carcinoma. In most cases it is associated with carcinoma in situ."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004114"
    },
    {
      "id": 5948,
      "label": "esophageal small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        5537,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7134",
          "GARD:0023832",
          "MEDGEN:207270",
          "NCIT:C6762",
          "UMLS:C1112474"
        ],
        "synonyms": [
          "Oat cell carcinoma of esophagus",
          "Oat cell carcinoma of the esophagus",
          "Oat cell carcinoma of the oesophagus",
          "esophageal Oat cell carcinoma",
          "esophageal small cell NEC",
          "esophageal small cell carcinoma",
          "esophageal small cell neuroendocrine carcinoma",
          "esophagus Oat cell carcinoma",
          "esophagus small cell carcinoma",
          "oesophagus Oat cell carcinoma",
          "small cell carcinoma of esophagus",
          "small cell carcinoma of oesophagus",
          "small cell carcinoma of the esophagus",
          "small cell carcinoma of the oesophagus",
          "small cell carcinoma, esophagus",
          "small cell carcinoma, oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the esophagus. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004116"
    },
    {
      "id": 5949,
      "label": "ampulla of vater small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        16046,
        17870,
        21453
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7136",
          "GARD:0023833",
          "MEDGEN:233974",
          "NCIT:C6655",
          "UMLS:C1332250"
        ],
        "synonyms": [
          "ampulla of Vater small cell NEC",
          "ampulla of Vater small cell carcinoma",
          "ampulla of Vater small cell neuroendocrine carcinoma",
          "ampullary small cell carcinoma",
          "hepatopancreatic ampulla small cell carcinoma",
          "small cell neuroendocrine carcinoma of the ampullary region"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive neuroendocrine carcinoma arising from the ampulla of Vater and the periampullary region. Morphologically, it is characterized by the presence of small malignant cells, necrosis, and a high mitotic rate. Signs and symptoms include jaundice, abdominal pain, anorexia, nausea, vomiting, and weight loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004117"
    },
    {
      "id": 5951,
      "label": "Bartholin gland small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4848,
        23671
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7140",
          "GARD:0023834",
          "MEDGEN:267705",
          "NCIT:C40298",
          "UMLS:C1511051"
        ],
        "synonyms": [
          "Bartholin gland small cell carcinoma",
          "Bartholin's gland small cell carcinoma",
          "major vestibular gland small cell carcinoma",
          "small cell carcinoma of major vestibular gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare neuroendocrine carcinoma that arises from the Bartholin gland and is characterized by the presence of malignant small cells and high mitotic activity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004120"
    },
    {
      "id": 5952,
      "label": "thymus small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        19965
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7142",
          "EFO:1000578",
          "GARD:0023835",
          "MEDGEN:234784",
          "NCIT:C6460",
          "UMLS:C1335980"
        ],
        "synonyms": [
          "Thymus small cell carcinoma",
          "small cell carcinoma of Thymus",
          "small cell carcinoma of the Thymus",
          "small cell carcinoma of thymus",
          "thymic small cell carcinoma",
          "thymic small cell carcinoma neuroendocrine type",
          "thymus small cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An aggressive, small cell, poorly differentiated thymic neuroendocrine carcinoma, characterized by the presence of a high mitotic rate and numerous apoptotic bodies."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004122"
    },
    {
      "id": 7705,
      "label": "cervical small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        6855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6740",
          "EFO:1000171",
          "GARD:0024309",
          "MEDGEN:79025",
          "NCIT:C7982",
          "ONCOTREE:SCCE",
          "UMLS:C0279674"
        ],
        "synonyms": [
          "Cervical small cell cancer",
          "cervical small cell carcinoma",
          "cervix small cell carcinoma",
          "cervix uteri small cell carcinoma",
          "small cell carcinoma of cervix",
          "small cell carcinoma of cervix uteri",
          "small cell carcinoma of the cervix",
          "small cell carcinoma of the cervix uteri",
          "small cell carcinoma of the uterine cervix",
          "small cell carcinoma of uterine cervix",
          "uterine cervix small cell carcinoma",
          "SCCE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A small cell carcinoma arising from the cervix."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006142"
    },
    {
      "id": 7752,
      "label": "endometrial small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4530
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7139",
          "EFO:1000239",
          "GARD:0024324",
          "MEDGEN:309057",
          "NCIT:C40155",
          "UMLS:C1516858",
          "icd11.foundation:845680139"
        ],
        "synonyms": [
          "endometrial small cell carcinoma",
          "endometrium small cell carcinoma",
          "small cell carcinoma of endometrium"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A primary carcinoma of the endometrium that is similar to the small cell carcinoma of the lung, histologically."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006197"
    },
    {
      "id": 7772,
      "label": "gallbladder small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        5174,
        21455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7133",
          "EFO:1000266",
          "GARD:0024335",
          "MEDGEN:232229",
          "NCIT:C6763",
          "UMLS:C1333759"
        ],
        "synonyms": [
          "Oat cell carcinoma of gallbladder",
          "Oat cell carcinoma of the gallbladder",
          "gall bladder small cell carcinoma",
          "gallbladder Oat cell carcinoma",
          "gallbladder small cell NEC",
          "gallbladder small cell carcinoma",
          "gallbladder small cell neuroendocrine carcinoma",
          "small cell carcinoma of gall bladder",
          "small cell carcinoma of gallbladder",
          "small cell carcinoma of the gallbladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gallbladder. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006219"
    },
    {
      "id": 7782,
      "label": "gastric small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        5092,
        6695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6552",
          "EFO:1000277",
          "GARD:0024342",
          "MEDGEN:272664",
          "NCIT:C6764",
          "ONCOTREE:STSC",
          "UMLS:C1333788"
        ],
        "synonyms": [
          "Oat cell carcinoma of stomach",
          "Oat cell carcinoma of the stomach",
          "gastric Oat cell carcinoma",
          "gastric small cell carcinoma",
          "gastric small cell neuroendocrine carcinoma",
          "small cell carcinoma of stomach",
          "small cell carcinoma of the stomach",
          "stomach small cell carcinoma",
          "STSC"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the stomach. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006229"
    },
    {
      "id": 7809,
      "label": "laryngeal small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4185,
        4457,
        16044
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7144",
          "EFO:1000320",
          "GARD:0024352",
          "MEDGEN:233611",
          "NCIT:C6025",
          "UMLS:C1334378"
        ],
        "synonyms": [
          "laryngeal small cell carcinoma",
          "laryngeal throat small cell cancer",
          "larynx small cell carcinoma",
          "small cell carcinoma of larynx",
          "small cell carcinoma of the larynx"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A rare carcinoma that arises from the larynx. It is characterized by the presence of small neuroendocrine cells. It metastasizes early and has an aggressive clinical course."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006265"
    },
    {
      "id": 7874,
      "label": "pancreatic small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        7497
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000444",
          "GARD:0024377",
          "MEDGEN:459466",
          "NCIT:C95583",
          "UMLS:C2987240"
        ],
        "synonyms": [
          "endocrine pancreas small cell carcinoma",
          "pancreatic small cell NEC",
          "pancreatic small cell NEC G3",
          "pancreatic small cell neuroendocrine carcinoma",
          "small cell carcinoma of endocrine pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006348"
    },
    {
      "id": 7910,
      "label": "prostate small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4557,
        6882
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7141",
          "EFO:1000499",
          "GARD:0024395",
          "MEDGEN:266251",
          "NCIT:C6766",
          "ONCOTREE:PRSCC",
          "SCTID:396198006",
          "UMLS:C1300585"
        ],
        "synonyms": [
          "Oat cell carcinoma of prostate",
          "Oat cell carcinoma of the prostate",
          "prostate Oat cell carcinoma",
          "prostate gland small cell carcinoma",
          "prostate oat cell carcinoma",
          "prostate small cell NEC",
          "prostate small cell carcinoma",
          "prostate small cell neuroendocrine carcinoma",
          "small cell carcinoma of prostate",
          "small cell carcinoma of prostate gland",
          "small cell carcinoma of the prostate",
          "PRSCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma of the prostate gland with unfavorable prognosis, composed of small cells containing neurosecretory granules. Approximately half of the cases show a mixture of small cells and adenocarcinoma cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006390"
    },
    {
      "id": 7924,
      "label": "salivary gland small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        2972,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000519",
          "GARD:0024400",
          "MEDGEN:234786",
          "NCIT:C35703",
          "UMLS:C1335982"
        ],
        "synonyms": [
          "anaplastic small cell carcinoma of salivary gland",
          "anaplastic small cell carcinoma of the salivary gland",
          "neuroendocrine carcinoma of salivary gland",
          "neuroendocrine carcinoma of the salivary gland",
          "saliva-secreting gland small cell carcinoma",
          "salivary gland anaplastic small cell carcinoma",
          "salivary gland small cell carcinoma",
          "small cell carcinoma of saliva-secreting gland",
          "small cell salivary gland carcinoma",
          "salivary gland neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An infrequent small cell carcinoma that arises from the salivary glands and is characterized by the presence of a high number of mitotic figures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006405"
    },
    {
      "id": 7979,
      "label": "ureter small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6886",
          "GARD:0024430",
          "MEDGEN:234971",
          "NCIT:C6176",
          "UMLS:C1336878"
        ],
        "synonyms": [
          "small cell carcinoma of the ureter",
          "small cell carcinoma of ureter",
          "ureter small cell carcinoma",
          "ureteral small cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare carcinoma that arises from the ureter. It is characterized by the presence of small neuroendocrine cells. The prognosis is poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006482"
    },
    {
      "id": 9726,
      "label": "small cell lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2894,
        6862,
        7117
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5409",
          "DOID:5411",
          "EFO:0000702",
          "GARD:0009344",
          "ICD9:162.9",
          "MEDGEN:57450",
          "MESH:D055752",
          "NCIT:C4917",
          "OMIM:182280",
          "ONCOTREE:SCLC",
          "Orphanet:70573",
          "SCTID:254632001",
          "UMLS:C0149925",
          "icd11.foundation:1800431439"
        ],
        "synonyms": [
          "SCLC",
          "oat cell carcinoma",
          "oat cell carcinoma (morphologic abnormality)",
          "poorly differentiated endocrine neoplasm",
          "Small cell lung cancer",
          "lung oat cell carcinoma",
          "lung small cell carcinoma",
          "lung small cell neuroendocrine carcinoma",
          "oat cell carcinoma of lung",
          "oat cell carcinoma of the lung",
          "oat cell lung carcinoma",
          "small cell cancer of the lung, somatic",
          "small cell carcinoma of lung",
          "small cell carcinoma of the lung",
          "small cell lung cancer",
          "small cell neuroendocrine carcinoma of lung",
          "small cell neuroendocrine carcinoma of the lung",
          "small-cell cancer of lung",
          "SCLC1",
          "small cell cancer of the lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008433"
    }
  ],
  "roots": [
    {
      "id": 4255,
      "label": "neuroendocrine carcinoma"
    }
  ]
}