{
  "id": 2897,
  "label": "fetal alcohol spectrum disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000408",
  "properties": {
    "xrefs": [
      "DOID:0050696",
      "MEDGEN:457516",
      "MESH:D063647",
      "NCIT:C92780",
      "SCTID:609437000",
      "UMLS:C2985290"
    ],
    "synonyms": [
      "fetal alcohol spectrum disorders",
      "foetal alcohol spectrum disorders",
      "FAE (fetal alcohol effects)",
      "FAEs (fetal alcohol effects)",
      "FASD",
      "FASDs",
      "alcohol related birth defects",
      "alcohol related neurodevelopmental disorder",
      "alcohol-related birth defects",
      "alcohol-related birth defects (ARBD) - type",
      "alcohol-related neurodevelopmental disorder (ARND) - type",
      "birth defects, alcohol-related",
      "fetal alcohol syndrome",
      "fetal alcohol syndrome (FAS) - type",
      "foetal alcohol syndrome",
      "foetal alcohol syndrome (FAS) - type",
      "growth retardation, facial abnormalities, and central nervous system dysfunction",
      "partial fetal alcohol syndrome",
      "partial foetal alcohol syndrome",
      "syndrome, fetal alcohol",
      "syndrome, foetal alcohol"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 3008,
      "label": "specific developmental disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7159
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060038",
          "ICD9:315.8",
          "MEDGEN:508157",
          "SCTID:10720004",
          "UMLS:C0037785"
        ],
        "synonyms": [
          "specific delays in development"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination."
      },
      "child_count": 10,
      "reference_id": "MONDO:0000592"
    },
    {
      "id": 4432,
      "label": "alcohol-induced mental disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6812
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:251",
          "ICD9:291.8",
          "ICD9:291.89",
          "MEDGEN:1705315",
          "UMLS:C5200920"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0002326"
    },
    {
      "id": 20730,
      "label": "alcohol-induced disorders",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:65935",
          "MESH:D020751",
          "SCTID:719848005",
          "UMLS:C0236970"
        ],
        "synonyms": [
          "alcohol induced disorders",
          "alcohol-induced disorder"
        ],
        "definition": "Disorders stemming from the misuse and abuse of alcohol."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021699"
    }
  ],
  "children": [
    {
      "id": 2889,
      "label": "partial fetal alcohol syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2897
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050666",
          "MEDGEN:775682",
          "UMLS:C3661483"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A fetal alcohol spectrum disorder that results in most, but not all, of the growth deficiency and/or craniofacial features of fetal alcohol syndrome including central nervous system dysfunction due to prenatal alcohol exposure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000393"
    },
    {
      "id": 2890,
      "label": "alcohol-related birth defect",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2897
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050668",
          "MEDGEN:459973",
          "NCIT:C92727",
          "UMLS:C3146244"
        ],
        "synonyms": [
          "ARBD",
          "alcohol related birth defect"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000395"
    },
    {
      "id": 16653,
      "label": "fetal alcohol syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2897,
        4370,
        17143
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050665",
          "DOID:0050667",
          "ICD10CM:Q86.0",
          "MEDGEN:8820",
          "MedDRA:10016845",
          "NCIT:C84713",
          "Orphanet:1915",
          "SCTID:205788004",
          "UMLS:C0015923",
          "icd11.foundation:362980699"
        ],
        "synonyms": [
          "FASD",
          "fetal alcohol spectrum disorders",
          "foetal alcohol spectrum disorders",
          "ARBD",
          "ARND",
          "FAS",
          "alcohol-related neurodevelopmental disorder",
          "alcohol-related birth defects",
          "static encephalopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Fetal alcohol syndrome (FAS) is a rare malformation syndrome caused by excessive maternal consumption of alcohol during pregnancy. It is characterized by prenatal and/or postnatal growth deficiency (weight and/or height <10th percentile), a unique cluster of minor facial anomalies (short palpebral fissures, flat and smooth philtrum, and thin upper lip) and severe central nervous system (CNS) abnormalities including microcephaly, and cognitive and behavioral impairment (intellectual disability, deficit in general cognition, learning and language, executive function, visual-spatial processing, memory, and attention)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016011"
    },
    {
      "id": 25230,
      "label": "neurobehavioral disorder with prenatal alcohol exposure",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2897
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081052"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A fetal alcohol spectrum disorder that is characterized by one or more deficits in neurocognition and in self-regulation plus two or more deficits in adaptive functioning, with at least 1 in communication or social communication and interaction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850461"
    }
  ],
  "roots": [
    {
      "id": 3008,
      "label": "specific developmental disorder"
    },
    {
      "id": 4432,
      "label": "alcohol-induced mental disorder"
    },
    {
      "id": 20730,
      "label": "alcohol-induced disorders"
    }
  ]
}