{
  "id": 2913,
  "label": "secondary progressive multiple sclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000450",
  "properties": {
    "xrefs": [
      "DOID:0050783",
      "EFO:0008522",
      "MEDGEN:155969",
      "NANDO:1200026",
      "NANDO:2201321",
      "SCTID:425500002",
      "UMLS:C0751965",
      "icd11.foundation:1045965709"
    ],
    "synonyms": [
      "SPMS",
      "secondary-progressive MS"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A multiple sclerosis with a clinical course characterized by a progressive accumulation of neurological disability, independent of relapses, following an initial relapsing-remitting (RR) phase."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6980,
      "label": "chronic progressive multiple sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6995
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003840",
          "MEDGEN:140733",
          "MESH:D020528",
          "SCTID:230373008",
          "UMLS:C0393665"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)"
      },
      "child_count": 3,
      "reference_id": "MONDO:0005284"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6980,
      "label": "chronic progressive multiple sclerosis"
    }
  ]
}