{
  "id": 2991,
  "label": "breast lobular carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000552",
  "properties": {
    "xrefs": [
      "DOID:0050938",
      "EFO:0008509",
      "ICDO:8520/3",
      "MEDGEN:64634",
      "NCIT:C3771",
      "SCTID:278054005",
      "UMLS:C0206692"
    ],
    "synonyms": [
      "carcinoma of lobule of mammary gland",
      "lobular adenocarcinoma",
      "lobular breast carcinoma",
      "lobular carcinoma",
      "lobular carcinoma of breast",
      "lobular carcinoma of the breast",
      "lobule of mammary gland carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "An adenocarcinoma of the breast arising from the lobules. This is a relatively uncommon carcinoma, represents approximately 10% of the breast adenocarcinomas and is often bilateral or multifocal."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6729,
      "label": "breast adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3053,
        6712,
        6730
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3458",
          "EFO:0000304",
          "MEDGEN:167809",
          "NCIT:C5214",
          "UMLS:C0858252"
        ],
        "synonyms": [
          "adenocarcinoma of breast",
          "adenocarcinoma of the breast",
          "breast adenocarcinoma",
          "mammary adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the breast"
      },
      "child_count": 39,
      "reference_id": "MONDO:0004988"
    }
  ],
  "children": [
    {
      "id": 6782,
      "label": "invasive lobular breast carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2991,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3457",
          "EFO:0000553",
          "MEDGEN:75994",
          "NCIT:C7950",
          "ONCOTREE:ILC",
          "UMLS:C0279565"
        ],
        "synonyms": [
          "lobular carcinoma",
          "lobular carcinoma (morphologic abnormality)",
          "lobular carcinoma NOS (morphologic abnormality)",
          "lobular carcinoma of the breast",
          "classic invasive lobular carcinoma",
          "infiltrating lobular adenocarcinoma",
          "infiltrating lobular breast carcinoma",
          "infiltrating lobular carcinoma of breast",
          "infiltrating lobular carcinoma of the breast",
          "invasive lobular adenocarcinoma",
          "invasive lobular breast carcinoma",
          "invasive lobular carcinoma",
          "invasive lobular carcinoma of breast",
          "invasive lobular carcinoma of the breast",
          "invasive lobular carcinoma, classic type",
          "breast invasive lobular carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An infiltrating lobular adenocarcinoma of the breast. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or as narrow trabeculae within the stroma. The malignant cells are usually smaller than those of ductal carcinoma, are less pleomorphic, and have fewer mitotic figures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005051"
    },
    {
      "id": 23994,
      "label": "CTNNA1-related diffuse gastric and lobular breast cancer syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2991,
        6770,
        16935,
        18536
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026099"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Germline pathogenic or likely pathogenic variants in the CTNNA1 gene predispose to hereditary diffuse gastric cancer and lobular breast cancer, a cancer susceptibility syndrome inherited in an autosomal dominant pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100256"
    }
  ],
  "roots": [
    {
      "id": 6729,
      "label": "breast adenocarcinoma"
    }
  ]
}