{
  "id": 2995,
  "label": "infective endocarditis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000565",
  "properties": {
    "xrefs": [
      "DOID:0060000",
      "GARD:0006337",
      "ICD9:136.9",
      "MEDGEN:323818",
      "NCIT:C78265",
      "NORD:1091",
      "Orphanet:570762",
      "SCTID:233850007",
      "UMLS:C1541923",
      "icd11.foundation:512128824"
    ],
    "synonyms": [
      "endocarditis infective",
      "endocarditis, infective"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Infective endocarditis (IE) is an infection of the inner lining of the heart chambers (endocardium) and valves. This condition is sometimes called 'endocarditis,' although it is important to distinguish it from non-infective endocarditis. IE is caused bybacteria, fungi, or other germs invading the bloodstream and attaching to the heart. IE can damagethe heart and cause serious and sometimes fatal complications. It can develop quickly or slowly depending on what type of germ is causing it and whether there is an underlying heart problem. Common symptoms of IE are fever and other flu-like symptoms, but signs and symptoms can vary. It can also cause problems in many other parts of the body besides the heart. IE is typically treated with antibiotics for several weeks; some individuals may need heart surgery to repair or replace heart valves or remove infected heart tissue."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6759,
      "label": "endocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2931,
        21547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10314",
          "EFO:0000465",
          "HP:0100584",
          "ICD9:421.9",
          "ICD9:424.99",
          "MEDGEN:4940",
          "MESH:D004696",
          "NCIT:C34582",
          "SCTID:56819008",
          "UMLS:C0014118"
        ],
        "synonyms": [
          "endocarditis",
          "endocarditis (disease)",
          "endocardium inflammation",
          "inflammation of endocardium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inflammation of the endocardium."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005025"
    },
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 8138,
      "label": "bacterial endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2995,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000830",
          "GARD:0024456",
          "HP:0006689",
          "MEDGEN:41779",
          "MESH:D004697",
          "MedDRA:10004019",
          "NCIT:C128359",
          "SCTID:301183007",
          "UMLS:C0014121",
          "icd11.foundation:1924438986"
        ],
        "synonyms": [
          "Bacteria caused endocarditis (disease)",
          "Bacteria endocarditis (disease)",
          "bacterial endocarditis",
          "bacterial endocarditis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Endocarditis that is caused by an infection with a bacterial agent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006669"
    },
    {
      "id": 8406,
      "label": "subacute bacterial endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2995,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4562",
          "EFO:1001193",
          "GARD:0024510",
          "MEDGEN:41780",
          "MESH:D004698",
          "MedDRA:10042271",
          "NCIT:C34583",
          "SCTID:73774007",
          "UMLS:C0014122",
          "icd11.foundation:933942548"
        ],
        "synonyms": [
          "SBE",
          "Subacute bacterial endocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Subacute inflammation of the endocardium. Streptococcus viridans is the usual etiologic agent of subacute bacterial endocarditis. The distinction between \"acute\" and \"subacute\" endocarditis has traditionally been made based on the pathogenic organism and clinical presentation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006981"
    },
    {
      "id": 23054,
      "label": "mycotic endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2995,
        4188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025844",
          "MEDGEN:547460",
          "SCTID:86348002",
          "UMLS:C0276648",
          "icd11.foundation:1487619220"
        ],
        "synonyms": [
          "Fungi caused endocarditis (disease)",
          "Fungi endocarditis (disease)",
          "mycotic endocarditis",
          "fungal endocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An endocarditis (disease) caused by infection with Fungi."
      },
      "child_count": 0,
      "reference_id": "MONDO:0042433"
    }
  ],
  "roots": [
    {
      "id": 6759,
      "label": "endocarditis"
    },
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}