{
  "id": 3019,
  "label": "primary cutaneous T-cell non-Hodgkin lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000607",
  "properties": {
    "xrefs": [
      "DOID:0060061",
      "EFO:0002913",
      "GARD:0022811",
      "ICDO:9709/3",
      "MESH:D016410",
      "NCIT:C3467"
    ],
    "synonyms": [
      "CTCL",
      "PCTCL",
      "T-cell non-Hodgkin's lymphoma of skin",
      "T-cell non-Hodgkin's lymphoma of the skin",
      "cutaneous T cell lymphoma",
      "cutaneous T-cell lymphoma",
      "cutaneous T-cell non-Hodgkin lymphoma",
      "cutaneous T-cell non-Hodgkin's lymphoma",
      "primary cutaneous T-cell non-Hodgkin lymphoma",
      "primary cutaneous T-cell non-Hodgkin's lymphoma",
      "skin T-cell non-Hodgkin's lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A T-cell non-Hodgkin lymphoma arising from the skin. Representative examples include mycosis fungoides and primary cutaneous anaplastic large cell lymphoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 18826,
      "label": "primary cutaneous lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        17548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018698",
          "MEDGEN:220981",
          "MedDRA:10051708",
          "NCIT:C7162",
          "Orphanet:542",
          "SCTID:400001003",
          "UMLS:C1302772"
        ],
        "synonyms": [
          "cutaneous (skin) lymphoma",
          "primary cutaneous lymphoma",
          "primary skin lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Cutaneous lymphoma is a heterogeneous entity with respect to its clinical and pathological features, evolutive profile, prognosis, molecular etiology and response to therapy. These specifications have been taken into account in recent classifications, which have placed particular importance on the prognostic implications of these different entities."
      },
      "child_count": 6,
      "reference_id": "MONDO:0018898"
    }
  ],
  "children": [
    {
      "id": 10905,
      "label": "mycosis fungoides",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3019,
        16571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8691",
          "EFO:1001051",
          "GARD:0003863",
          "ICD10CM:C84.0",
          "ICD9:202.1",
          "ICDO:9700/3",
          "MEDGEN:7771",
          "MESH:D009182",
          "MedDRA:10028483",
          "NCIT:C3246",
          "NORD:1479",
          "OMIM:254400",
          "ONCOTREE:MYCF",
          "Orphanet:2584",
          "SCTID:118618005",
          "UMLS:C0026948",
          "icd11.foundation:901411509"
        ],
        "synonyms": [
          "CTCL/ mycosis fungoides",
          "MF",
          "cutaneous T-cell lymphoma/mycosis fungoides",
          "mycosis fungoides",
          "mycosis fungoides (morphologic abnormality)",
          "mycosis fungoides NOS (morphologic abnormality)",
          "mycosis fungoides of unspecified site",
          "mycosis fungoides, Alibert-Bazin type",
          "mycosis fungoides, unspecified site, extranodal and solid organ sites",
          "Alibert-Bazin syndrome",
          "classic mycosis fungoides",
          "granuloma fungoides"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Classical mycosis fungoides is the most common type of mycosis fungoides (MF), a form of cutaneous T-cell lymphoma, and is characterized by slow progression from patches to more infiltrated plaques and eventually to tumors."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009691"
    },
    {
      "id": 17878,
      "label": "primary cutaneous anaplastic large cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3019,
        18825,
        19798,
        20048
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021247",
          "MEDGEN:266255",
          "MESH:D054446",
          "MedDRA:10065863",
          "NCIT:C6860",
          "ONCOTREE:PCALCL",
          "Orphanet:300865",
          "UMLS:C1301362",
          "icd11.foundation:1972636482"
        ],
        "synonyms": [
          "ALCL, cutaneous",
          "C-ALCL",
          "anaplastic large-cell lymphoma, primary cutaneous type",
          "primary C-ALCL",
          "primary anaplastic large cell lymphoma of skin",
          "primary anaplastic large cell lymphoma of the skin",
          "primary cutaneous CD30 Positive anaplastic large cell lymphoma",
          "primary cutaneous CD30+ ALCL",
          "primary cutaneous CD30+ anaplastic large cell lymphoma",
          "regressive atypical histiocytosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare T-cell non-Hodgkin lymphoma that affects the skin and generally shows no extracutaneous involvement at presentation. It belongs to the spectrum of primary cutaneous CD30+ lymphoproliferative disorders along with lymphomatoid papulosis with which it shares overlapping clinical and histopathologic features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017598"
    },
    {
      "id": 18061,
      "label": "Sezary syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8541",
          "EFO:1000785",
          "GARD:0007629",
          "ICD9:202.2",
          "ICDO:9701/3",
          "MEDGEN:19959",
          "MESH:D012751",
          "MedDRA:10040493",
          "MedDRA:10040500",
          "NCIT:C3366",
          "NORD:1707",
          "ONCOTREE:SS",
          "Orphanet:3162",
          "SCTID:118611004",
          "UMLS:C0036920",
          "icd11.foundation:1358020385"
        ],
        "synonyms": [
          "CTCL / Sezary syndrome",
          "SC)zary syndrome",
          "Sezary disease",
          "Sezary lymphoma",
          "Sezary syndrome",
          "Sezary's disease",
          "Sheehan Syndrome",
          "Sézary lymphoma",
          "Sézary syndrome",
          "cutaneous T-cell lymphoma/Sezary syndrome",
          "SS",
          "Sezary's lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Sezary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sezary cells)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017844"
    },
    {
      "id": 23551,
      "label": "mycosis fungoides variant",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3019,
        16571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025943",
          "MEDGEN:271222",
          "NCIT:C39644",
          "UMLS:C1513782"
        ],
        "synonyms": [
          "mycosis fungoides variant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0045071"
    },
    {
      "id": 25229,
      "label": "primary cutaneous gamma-delta t-cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081050",
          "GARD:0026621",
          "MEDGEN:313069",
          "NCIT:C45340",
          "UMLS:C1707547"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A primary cutaneous T-cell non-Hodgkin lymphoma that is characterized by the clonal cutaneous proliferation of activated mature gamma-delta T cells with a cytotoxic phenotype."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850459"
    }
  ],
  "roots": [
    {
      "id": 18826,
      "label": "primary cutaneous lymphoma"
    }
  ]
}