{
  "id": 3027,
  "label": "breast benign neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000620",
  "properties": {
    "xrefs": [
      "DOID:0060082",
      "ICD10CM:D24",
      "ICD9:217",
      "MEDGEN:91085",
      "NCIT:C4505",
      "SCTID:269485000",
      "UMLS:C0346156",
      "icd11.foundation:2120366482"
    ],
    "synonyms": [
      "benign breast neoplasm",
      "benign breast tumor",
      "benign breast tumour",
      "benign neoplasm of breast",
      "benign neoplasm of the breast",
      "benign tumor of breast",
      "benign tumor of the breast",
      "benign tumour of breast",
      "benign tumour of the breast",
      "breast benign neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A non-metastasizing neoplasm arising from the breast parenchyma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 15,
  "parents": [
    {
      "id": 3039,
      "label": "thoracic benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060097",
          "ICD9:229.8",
          "MEDGEN:138065",
          "NCIT:C4565",
          "SCTID:255059002",
          "UMLS:C0346440"
        ],
        "synonyms": [
          "benign neoplasm of the thorax",
          "benign neoplasm of thorax",
          "benign thoracic neoplasm",
          "benign thoracic tumor",
          "benign thoracic tumour",
          "benign tumor of the thorax",
          "benign tumor of thorax",
          "benign tumour of the thorax",
          "benign tumour of thorax",
          "thoracic segment of trunk benign neoplasm"
        ],
        "definition": "A non-metastasizing neoplasm arising from any of the organs of the thoracic cavity. Representative examples include pleural adenomatoid tumor, chest wall lipoma, mediastinal schwannoma, and lung hamartoma."
      },
      "child_count": 16,
      "reference_id": "MONDO:0000634"
    },
    {
      "id": 20340,
      "label": "breast neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4708,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003869",
          "ICD9:239.3",
          "MEDGEN:264172",
          "MESH:D001943",
          "NCIT:C2910",
          "ONCOTREE:BREAST",
          "SCTID:126926005",
          "UMLS:C1458155"
        ],
        "synonyms": [
          "breast neoplasm",
          "breast neoplasm (disease)",
          "breast tumor",
          "breast tumour",
          "neoplasm of breast",
          "neoplasm of the breast",
          "neoplasm, breast",
          "tumor of breast",
          "tumor of the breast",
          "tumour of breast",
          "tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021100"
    }
  ],
  "children": [
    {
      "id": 3239,
      "label": "breast lipoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        6833
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10199",
          "ICD9:214.1",
          "MEDGEN:138103",
          "NCIT:C4647",
          "SCTID:276891009",
          "UMLS:C0349565"
        ],
        "synonyms": [
          "breast lipoma",
          "lipoma of breast",
          "lipoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, mesenchymal neoplasm that arises from the breast. It is surrounded by a thin capsule and composed of mature adipose tissue cells. Atypia is absent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000970"
    },
    {
      "id": 3273,
      "label": "breast cyst",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3027
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10350",
          "MEDGEN:14220",
          "MESH:D047688",
          "SCTID:399294002",
          "UMLS:C0006144"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A cystic lesion located in breast tissue."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001011"
    },
    {
      "id": 4200,
      "label": "benign eccrine breast spiradenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        5374
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1616",
          "GARD:0027596",
          "MEDGEN:231933",
          "NCIT:C5193",
          "UMLS:C1332492"
        ],
        "synonyms": [
          "benign breast eccrine spiradenoma",
          "benign eccrine breast spiradenoma",
          "benign eccrine spiradenoma of breast",
          "benign eccrine spiradenoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A very rare, benign sweat gland neoplasm that affects the breast. It is characterized by the proliferation of basaloid epithelial cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002055"
    },
    {
      "id": 4201,
      "label": "breast fibroadenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3027,
        20290
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1618",
          "ICDO:9010/0",
          "MEDGEN:64231",
          "MESH:D018226",
          "NCIT:C3744",
          "ONCOTREE:FA",
          "SCTID:254847007",
          "UMLS:C0178421",
          "icd11.foundation:143326763"
        ],
        "synonyms": [
          "breast fibroadenoma",
          "fibroadenoma",
          "fibroadenoma of breast",
          "fibroadenoma of the breast",
          "fibroadenoma, benign",
          "juvenile fibroadenoma (morphologic abnormality)",
          "FA"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign tumor of the breast characterized by the presence of stromal and epithelial elements. It presents as a painless, solitary, slow growing, firm, and mobile mass. It is the most common benign breast lesion. It usually occurs in women of childbearing age. The majority of fibroadenomas do not recur after complete excision. A slightly increased risk of developing cancer within fibroadenomas or in the breast tissue of patients previously treated for fibroadenomas has been reported."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002056"
    },
    {
      "id": 4202,
      "label": "breast leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        3776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1623",
          "MEDGEN:267768",
          "NCIT:C40399",
          "UMLS:C1511317",
          "icd11.foundation:214325738"
        ],
        "synonyms": [
          "breast leiomyoma",
          "leiomyoma of breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A well-circumscribed benign smooth muscle neoplasm arising from the breast. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002057"
    },
    {
      "id": 4203,
      "label": "breast adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3027,
        6714,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1625",
          "MEDGEN:231286",
          "NCIT:C40382",
          "UMLS:C1328385"
        ],
        "synonyms": [
          "breast adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign, well circumscribed neoplasm that arises from the breast. Representative examples include apocrine adenoma, tubular adenoma, and pleomorphic adenoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002058"
    },
    {
      "id": 4206,
      "label": "breast myofibroblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        23002
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1629",
          "MEDGEN:307311",
          "NCIT:C40397",
          "UMLS:C1511320"
        ],
        "synonyms": [
          "breast myofibroblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A myofibroblastoma occurring in the breast of both women and men. It presents as a slowly growing mass."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002062"
    },
    {
      "id": 4208,
      "label": "benign breast adenomyoepithelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        4209,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1641",
          "MEDGEN:231421",
          "NCIT:C5144",
          "UMLS:C1332477"
        ],
        "synonyms": [
          "benign adenomyoepithelioma of breast",
          "benign adenomyoepithelioma of the breast",
          "benign breast adenomyoepithelioma",
          "breast adenomyoepithelioma, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign, nodular tumor that arises from the breast parenchyma. It is characterized by the proliferation of myoepithelial cells around spaces that are lined by epithelial cells. Occasionally, adenomyoepitheliomas may undergo malignant transformation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002065"
    },
    {
      "id": 5103,
      "label": "breast hemangioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3027,
        7994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:476",
          "MEDGEN:163122",
          "NCIT:C5353",
          "UMLS:C0853715"
        ],
        "synonyms": [
          "angioma of breast",
          "angioma of the breast",
          "breast angioma",
          "breast hemangioma",
          "hemangioma of breast",
          "hemangioma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A capillary or cavernous hemangioma arising from the breast."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003126"
    },
    {
      "id": 15255,
      "label": "multiple fibroadenoma of the breast",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024980",
          "MEDGEN:816248",
          "OMIM:615554",
          "Orphanet:50920",
          "UMLS:C3809918"
        ],
        "synonyms": [
          "mammary polyadenomatosis",
          "MFAB",
          "multiple fibroadenomas of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "Mammary polyadenomatosis is characterized by the presence in both breasts of multiple voluminous fibroadenomas with heterogeneous echo patterns."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014249"
    },
    {
      "id": 16598,
      "label": "benign breast phyllodes tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027,
        20291,
        22954
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1631",
          "GARD:0009514",
          "MEDGEN:231438",
          "MedDRA:10011813",
          "NCIT:C5196",
          "ONCOTREE:BPT",
          "Orphanet:180261",
          "SCTID:720344007",
          "UMLS:C1332533",
          "icd11.foundation:827143668"
        ],
        "synonyms": [
          "benign phyllodes neoplasm",
          "phyllodes neoplasm",
          "phyllodes tumor, benign (morphologic abnormality)",
          "benign breast phyllodes tumor",
          "benign phyllodes neoplasm of breast",
          "benign phyllodes neoplasm of the breast",
          "benign phyllodes tumor of breast",
          "benign phyllodes tumor of the breast",
          "benign phyllodes tumour of breast",
          "benign phyllodes tumour of the breast",
          "breast benign phyllodes neoplasm",
          "breast phyllodes tumor, benign",
          "cystosarcoma phyllode of the breast",
          "cystosarcoma phylloide of the breast",
          "phylloide tumor of the breast",
          "phylloide tumour of the breast",
          "BPT",
          "benign cystosarcoma phyllodes",
          "cystosarcoma phyllode",
          "cystosarcoma phyllodes",
          "cystosarcoma phyllodes NOS (morphologic abnormality)",
          "cystosarcoma phylloide",
          "phyllode tumor of the breast",
          "phyllode tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A usually unilateral, benign and well circumscribed biphasic neoplasm that arises from the breast. It usually affects middle-aged women. It is characterized by the presence of a double layer of epithelial cells that are arranged in clefts, surrounded by a cellular, monomorphic spindle cell mesenchymal component. Mitoses are rare. Necrotic changes may be present in large tumors."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015871"
    },
    {
      "id": 20337,
      "label": "intraductal breast papilloma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3027,
        3052,
        4204,
        4205
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1626",
          "MEDGEN:65944",
          "NCIT:C3863",
          "SCTID:254848002",
          "SCTID:99571000119102",
          "UMLS:C0238034"
        ],
        "synonyms": [
          "breast papilloma",
          "duct papilloma of breast",
          "duct papilloma of the breast",
          "ductal breast papilloma",
          "intraductal breast papilloma",
          "intraductal papilloma of breast",
          "intraductal papilloma of the breast",
          "mammary duct papilloma",
          "papilloma of breast",
          "papilloma of the breast",
          "breast duct papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterized by fibrovascular structures lined by benign epithelial and myoepithelial proliferations. Intraductal breast papillomas are classified as central, when they arise in large ducts, or peripheral, when they arise in the terminal ductal lobular units."
      },
      "child_count": 20,
      "reference_id": "MONDO:0021097"
    },
    {
      "id": 20645,
      "label": "benign neoplasm of male breast",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:83867",
          "NCIT:C4620",
          "SCTID:92206006",
          "UMLS:C0347482"
        ],
        "synonyms": [
          "benign Male breast neoplasm",
          "benign Male breast tumor",
          "benign Male breast tumour",
          "benign neoplasm of the Male breast",
          "benign tumor of Male breast",
          "benign tumor of the Male breast",
          "benign tumour of Male breast",
          "benign tumour of the Male breast",
          "male breast benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the breast parenchyma in males."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021528"
    },
    {
      "id": 21075,
      "label": "diabetic mastopathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:419098",
          "MESH:C537524",
          "SCTID:724136006",
          "UMLS:C2931521"
        ],
        "synonyms": [
          "diabetic fibrous breast disease",
          "diabetic fibrous mastopathy",
          "lymphocytic mastitis",
          "lymphocytic mastopathy",
          "sclerosing lymphocytic lobulitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "Diabetic mastopathy are noncancerous lesions in the breast most commonly diagnosed in premenopausal women with type 1 diabetes. The cause of this condition is unknown. Symptoms may include hard, irregular, easily movable, discrete, painless breast mass(es)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022972"
    },
    {
      "id": 25822,
      "label": "lymphocytic mastitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3027
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026931",
          "Orphanet:653698"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0958101"
    }
  ],
  "roots": [
    {
      "id": 3039,
      "label": "thoracic benign neoplasm"
    },
    {
      "id": 20340,
      "label": "breast neoplasm"
    }
  ]
}