{
  "id": 3041,
  "label": "musculoskeletal system cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000637",
  "properties": {
    "xrefs": [
      "DOID:0060100",
      "MEDGEN:1714562",
      "NCIT:C166357",
      "UMLS:C0036210"
    ],
    "synonyms": [
      "cancer of musculoskeletal system",
      "malignant musculoskeletal system neoplasm",
      "malignant neoplasm of musculoskeletal system",
      "musculoskeletal system cancer",
      "skeletal system cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the musculoskeletal system"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:17",
          "EFO:0009676",
          "ICD9:729.99",
          "MEDGEN:6471",
          "MESH:D009140",
          "NCIT:C107377",
          "SCTID:928000",
          "UMLS:C0026857"
        ],
        "synonyms": [
          "disease of musculoskeletal system",
          "disease or disorder of musculoskeletal system",
          "disorder of musculoskeletal system",
          "musculoskeletal disease",
          "musculoskeletal system disease",
          "musculoskeletal system disease or disorder",
          "musculoskeletal system disorder",
          "musculoskeletal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease involving the musculoskeletal system."
      },
      "child_count": 22,
      "reference_id": "MONDO:0002081"
    },
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
          "DOID:162",
          "ICD9:195.8",
          "ICD9:199",
          "ICD9:199.1",
          "ICDO:8000/3",
          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
          "UMLS:C0006826",
          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    }
  ],
  "children": [
    {
      "id": 3042,
      "label": "cartilage cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3041,
        6893,
        20678
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060102",
          "GARD:0006004",
          "MEDGEN:1843449",
          "UMLS:C4290064"
        ],
        "synonyms": [
          "cancer of cartilage tissue",
          "cartilage tissue cancer",
          "cartilaginous cancer",
          "malignant cartilage tissue neoplasm",
          "malignant neoplasm of cartilage tissue"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A cancer involving a cartilage tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000639"
    },
    {
      "id": 3357,
      "label": "broad ligament malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        3576,
        23529
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10744",
          "ICD9:183.3",
          "MEDGEN:577691",
          "NCIT:C179934",
          "SCTID:449259009",
          "UMLS:C0346866"
        ],
        "synonyms": [
          "broad ligament of uterus cancer",
          "cancer of broad ligament of uterus",
          "malignant broad ligament of uterus neoplasm",
          "malignant neoplasm of broad ligament of uterus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the broad ligament of uterus."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001108"
    },
    {
      "id": 3577,
      "label": "round ligament malignant neoplasm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3041,
        3576,
        4227,
        23530
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11748",
          "ICD10CM:C57.2",
          "ICD9:183.5",
          "MEDGEN:577692",
          "SCTID:188204000",
          "UMLS:C0346867",
          "icd11.foundation:176621155"
        ],
        "synonyms": [
          "cancer of round ligament of uterus",
          "malignant neoplasm of round ligament",
          "malignant neoplasm of round ligament of uterus",
          "malignant round ligament of uterus neoplasm",
          "round ligament of uterus cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the round ligament of uterus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001352"
    },
    {
      "id": 3881,
      "label": "laryngeal cartilage cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3041,
        4451,
        6893
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13348",
          "GARD:0022988",
          "ICD10CM:C32.3",
          "ICD9:161.3",
          "MEDGEN:509306",
          "SCTID:363431006",
          "UMLS:C0153486",
          "icd11.foundation:697702574"
        ],
        "synonyms": [
          "cancer of laryngeal cartilage",
          "laryngeal cartilage cancer",
          "malignant laryngeal cartilage neoplasm",
          "malignant neoplasm of laryngeal cartilage",
          "malignant neoplasm of laryngeal cartilages",
          "malignant tumour of laryngeal cartilage"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the laryngeal cartilage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001691"
    },
    {
      "id": 4262,
      "label": "bone cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        18958
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2019-1041",
          "DOID:184",
          "EFO:1000350",
          "GARD:0023070",
          "ICD9:170.9",
          "MEDGEN:79002",
          "MESH:D001859",
          "NCIT:C4016",
          "SCTID:428281000",
          "UMLS:C0279530"
        ],
        "synonyms": [
          "bone neoplasm",
          "bone tumor",
          "bone tumour",
          "osseous tumor",
          "osseous tumour",
          "bone cancer",
          "cancer of bone",
          "cancer of skeletal element",
          "cancer of the bone",
          "malignant bone neoplasm",
          "malignant bone tumor",
          "malignant neoplasm of bone",
          "malignant neoplasm of skeletal element",
          "malignant neoplasm of the bone",
          "malignant osseous neoplasm",
          "malignant osseous tumor",
          "malignant osseous tumour",
          "malignant skeletal element neoplasm",
          "malignant tumor of bone",
          "malignant tumor of the bone",
          "malignant tumour of bone",
          "malignant tumour of the bone",
          "osseous cancer",
          "skeletal element cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the bone or articular cartilage."
      },
      "child_count": 24,
      "reference_id": "MONDO:0002129"
    },
    {
      "id": 4493,
      "label": "synovium cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        4597
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2706",
          "GARD:0027607",
          "MEDGEN:277340",
          "NCIT:C6531",
          "UMLS:C1334624"
        ],
        "synonyms": [
          "cancer of layer of synovial tissue",
          "cancer of synovial membrane of synovial joint",
          "layer of synovial tissue cancer",
          "malignant layer of synovial tissue neoplasm",
          "malignant neoplasm of layer of synovial tissue",
          "malignant neoplasm of synovial membrane of synovial joint",
          "malignant neoplasm of synovium",
          "malignant neoplasm of the synovium",
          "malignant synovial membrane of synovial joint neoplasm",
          "malignant synovial neoplasm",
          "malignant synovial tumor",
          "malignant synovial tumour",
          "malignant tumor of synovium",
          "malignant tumor of the synovium",
          "malignant tumour of synovium",
          "malignant tumour of the synovium",
          "synovial membrane of synovial joint cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A cancer that involves the layer of synovial tissue."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002403"
    },
    {
      "id": 5505,
      "label": "uterine ligament cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        4978,
        20685
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5727",
          "MEDGEN:923070",
          "NCIT:C126498",
          "UMLS:C0864950"
        ],
        "synonyms": [
          "cancer of uterine ligament",
          "malignant neoplasm of uterine ligament",
          "malignant uterine ligament neoplasm",
          "uterine ligament cancer",
          "tumour of the uterine ligament"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the uterine ligament."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003612"
    },
    {
      "id": 6428,
      "label": "tonsillar pillar cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3041,
        5798,
        8421
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8688",
          "GARD:0027696",
          "ICD10CM:C09.1",
          "ICD9:146.2",
          "MEDGEN:509270",
          "SCTID:187675005",
          "UMLS:C0153385"
        ],
        "synonyms": [
          "malignant neoplasm of tonsillar pillar",
          "malignant neoplasm of tonsillar pillars, posterior",
          "malignant tumor of tonsillar pillar"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A cancer that involves the tonsillar pillar."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004642"
    },
    {
      "id": 7163,
      "label": "gingival cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        7170,
        7266,
        20327
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8602",
          "EFO:0005557",
          "GARD:0024198",
          "ICD10CM:C03",
          "ICD9:143",
          "ICD9:143.8",
          "ICD9:143.9",
          "MEDGEN:57549",
          "MedDRA:10067807",
          "NCIT:C9317",
          "SCTID:363382005",
          "UMLS:C0153364",
          "icd11.foundation:1719710858"
        ],
        "synonyms": [
          "cancer of gingiva",
          "gingiva cancer",
          "malignant gingiva neoplasm",
          "malignant gingival neoplasm",
          "malignant gingival tumor",
          "malignant gingival tumour",
          "malignant gum neoplasm",
          "malignant gum tumor",
          "malignant gum tumour",
          "malignant neoplasm of gingiva",
          "malignant neoplasm of gum",
          "malignant neoplasm of the gingiva",
          "malignant neoplasm of the gum",
          "malignant tumor of gingiva",
          "malignant tumor of gum",
          "malignant tumor of the gingiva",
          "malignant tumor of the gum",
          "malignant tumour of gingiva",
          "malignant tumour of gum",
          "malignant tumour of the gingiva",
          "malignant tumour of the gum",
          "gum cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the gums."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005507"
    },
    {
      "id": 7472,
      "label": "muscle cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4045",
          "EFO:0007384",
          "ICD9:171.9",
          "ICDO:8895/3",
          "MEDGEN:151927",
          "NCIT:C4883",
          "SCTID:363495004",
          "UMLS:C0684743"
        ],
        "synonyms": [
          "cancer of muscle structure",
          "malignant muscle neoplasm",
          "malignant muscle structure neoplasm",
          "malignant muscle tumor",
          "malignant muscle tumour",
          "malignant neoplasm of muscle",
          "malignant neoplasm of muscle structure",
          "malignant neoplasm of the muscle",
          "malignant tumor of muscle",
          "malignant tumor of the muscle",
          "malignant tumour of muscle",
          "malignant tumour of the muscle",
          "muscle structure cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A malignant neoplasm affecting the skeletal or smooth muscles. Malignant neoplasms arising from the skeletal muscles are called rhabdomyosarcomas. Malignant neoplasms arising from the smooth muscles are called leiomyosarcomas."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005864"
    },
    {
      "id": 7657,
      "label": "ameloblastic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3041,
        4185,
        7738,
        20417
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000078",
          "GARD:0011855",
          "MEDGEN:231088",
          "NCIT:C7492",
          "NORD:763",
          "Orphanet:314422",
          "UMLS:C1314678"
        ],
        "synonyms": [
          "ameloblastic carcinoma",
          "odontoma, ameloblastic, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A rare, cytologically malignant ameloblastoma that may metastasize."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006079"
    }
  ],
  "roots": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder"
    },
    {
      "id": 6733,
      "label": "cancer"
    }
  ]
}