{
  "id": 3047,
  "label": "ovarian benign neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000646",
  "properties": {
    "xrefs": [
      "DOID:0060112",
      "EFO:1000116",
      "MEDGEN:14058",
      "NCIT:C2895",
      "SCTID:92260003",
      "UMLS:C0004997",
      "icd11.foundation:181365103"
    ],
    "synonyms": [
      "benign neoplasm of ovary",
      "benign neoplasm of the ovary",
      "benign ovarian neoplasm",
      "benign ovarian tumor",
      "benign ovarian tumour",
      "benign tumor of ovary",
      "benign tumor of the ovary",
      "benign tumour of ovary",
      "benign tumour of the ovary",
      "ovary benign neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumor, thecoma, and fibroma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 15,
  "parents": [
    {
      "id": 3029,
      "label": "benign female reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2882,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060086",
          "MEDGEN:152872",
          "NCIT:C4934",
          "UMLS:C0744514"
        ],
        "synonyms": [
          "benign female reproductive system neoplasm",
          "benign female reproductive system tumor",
          "benign female reproductive system tumour",
          "benign gynecologic neoplasm",
          "benign gynecologic tumor",
          "benign gynecologic tumour",
          "female reproductive organ benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, and benign ovarian germ cell tumor."
      },
      "child_count": 14,
      "reference_id": "MONDO:0000624"
    },
    {
      "id": 20309,
      "label": "ovarian neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7207,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003893",
          "ICD9:239.5",
          "MEDGEN:181539",
          "NCIT:C4984",
          "SCTID:123843001",
          "UMLS:C0919267"
        ],
        "synonyms": [
          "neoplasm of ovary",
          "neoplasm of the ovary",
          "ovarian neoplasm",
          "ovarian tumor",
          "ovarian tumors",
          "ovarian tumour",
          "ovarian tumours",
          "ovary neoplasm",
          "ovary neoplasm (disease)",
          "ovary tumor",
          "ovary tumour",
          "tumor of ovary",
          "tumor of the ovary",
          "tumour of ovary",
          "tumour of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant neoplasm involving the ovary."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021068"
    }
  ],
  "children": [
    {
      "id": 5271,
      "label": "benign struma ovarii",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        8405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5209",
          "GARD:0023455",
          "NCIT:C40012"
        ],
        "synonyms": [
          "benign struma ovarii",
          "struma ovarii, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A mature monodermal teratoma that arises from the ovary and is characterized by the presence of benign, thyroid-type tissues."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003333"
    },
    {
      "id": 5385,
      "label": "ovarian endometrioid adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5480",
          "ICDO:8380/0",
          "ICDO:8381/0",
          "MEDGEN:389179",
          "NCIT:C27287",
          "UMLS:C2212024"
        ],
        "synonyms": [
          "ovarian endometrioid adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm of the ovary characterized by the presence of glandular structures with endometrial-type well-differentiated cells in a fibrotic stroma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003463"
    },
    {
      "id": 5579,
      "label": "ovarian clear cell adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        5382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5897",
          "MEDGEN:309502",
          "NCIT:C40085",
          "UMLS:C1518694"
        ],
        "synonyms": [
          "clear cell adenofibroma of ovary",
          "ovarian clear cell adenofibroma",
          "ovary clear cell adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An uncommon benign neoplasm of glandular epithelium characterized by the presence of clear or hobnail cells within a dense fibrous stroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003695"
    },
    {
      "id": 5737,
      "label": "ovarian surface papilloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        4461,
        5686
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6407",
          "MEDGEN:235423",
          "NCIT:C7279",
          "UMLS:C1335183"
        ],
        "synonyms": [
          "ovarian surface papilloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign serous neoplasm characterized by the presence of papillary proliferations on the surface of the ovary."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003873"
    },
    {
      "id": 5749,
      "label": "ovarian mucinous adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        4347,
        4488
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6469",
          "MEDGEN:309511",
          "NCIT:C40040",
          "UMLS:C1518723"
        ],
        "synonyms": [
          "mucinous adenofibroma of ovary",
          "ovarian mucinous adenofibroma",
          "ovary mucinous adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm of the ovary characterized by the presence of glands with mucinous columnar epithelial cells in a fibrotic stroma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003887"
    },
    {
      "id": 5856,
      "label": "rete ovarii cystadenofibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        5151,
        5386
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6838",
          "MEDGEN:308159",
          "NCIT:C40020",
          "UMLS:C1514906"
        ],
        "synonyms": [
          "cystadenofibroma of rete ovarii",
          "rete ovarii cystadenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An exceptionally rare cystadenofibroma that arises from the rete ovarii."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004006"
    },
    {
      "id": 6900,
      "label": "ovarian adenoma benign",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        4347,
        6714,
        22952
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign adenoma of ovary"
      },
      "child_count": 8,
      "reference_id": "MONDO:0005179"
    },
    {
      "id": 7868,
      "label": "ovarian serous adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        21610
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5474",
          "EFO:1000428",
          "MEDGEN:309514",
          "NCIT:C40031",
          "UMLS:C1518729"
        ],
        "synonyms": [
          "ovarian serous adenofibroma",
          "ovary serous adenofibroma",
          "serous adenofibroma of ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm of the ovary characterized by the presence of glands with serous epithelial cells in a fibrotic stroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006340"
    },
    {
      "id": 9479,
      "label": "ovarian fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021375",
          "HP:0010618",
          "MEDGEN:57706",
          "MESH:C562391",
          "MedDRA:10064257",
          "NCIT:C3498",
          "OMIM:166970",
          "Orphanet:314473",
          "SCTID:254865006",
          "UMLS:C0149951",
          "icd11.foundation:871413134"
        ],
        "synonyms": [
          "fibroma of ovary",
          "fibroma of the ovary",
          "ovarian fibroma",
          "ovarian fibroma (disease)",
          "ovarian fibromata"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm arising from soft tissue of the ovary. It is characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008168"
    },
    {
      "id": 16719,
      "label": "serous or mucinous cystadenoma of childhood",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020346",
          "MEDGEN:1803886",
          "Orphanet:206470",
          "UMLS:C5679785"
        ],
        "synonyms": [
          "mucinous cystadenoma of ovary in childhood",
          "serous cystadenoma of ovary in childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Serous or mucinous cystadenoma of childhood is a benign epithelial ovarian tumor characterized by a usually unilateral, cystic, unilocular or multilocular lesion with a thin wall or septa and no intracystic solid portion on imaging. It often presents with abdominal pain or an asymptomatic abdominal mass and can be associated with ovarian torsion or malignant transformation."
      },
      "child_count": 3,
      "reference_id": "MONDO:0016092"
    },
    {
      "id": 18020,
      "label": "Meigs syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        20301
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021372",
          "ICD9:629.89",
          "MEDGEN:6287",
          "MESH:D008539",
          "MedDRA:10027139",
          "NCIT:C3223",
          "Orphanet:314451",
          "SCTID:63402005",
          "UMLS:C0025184",
          "icd11.foundation:1050919535"
        ],
        "synonyms": [
          "Demons-Meigs syndrome",
          "Meigs' syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare syndrome affecting females. It is characterized by pleural effusion, ascites and non-malignant ovarian neoplasm. This syndrome usually follows a benign course. Prognosis is favorable following surgical resection of the ovarian mass."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017799"
    },
    {
      "id": 18021,
      "label": "pseudo-Meigs syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021373",
          "MEDGEN:1678402",
          "Orphanet:314459",
          "UMLS:C5190824"
        ],
        "synonyms": [
          "pseudo-Demons-Meigs syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017800"
    },
    {
      "id": 18022,
      "label": "atypical Meigs syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021374",
          "MEDGEN:1676202",
          "Orphanet:314466",
          "UMLS:C5190605"
        ],
        "synonyms": [
          "atypical Demons-Meigs syndrome",
          "incomplete Meigs syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017801"
    },
    {
      "id": 21393,
      "label": "benign ovarian sex cord-stromal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        20709,
        21634
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080370",
          "GARD:0027915",
          "MEDGEN:231435",
          "NCIT:C6803",
          "UMLS:C1332528"
        ],
        "synonyms": [
          "Sex cord stromal tumor, benign",
          "benign Sex cord-stromal neoplasm of ovary",
          "benign Sex cord-stromal neoplasm of the ovary",
          "benign Sex cord-stromal tumor of ovary",
          "benign Sex cord-stromal tumor of the ovary",
          "benign Sex cord-stromal tumour of ovary",
          "benign Sex cord-stromal tumour of the ovary",
          "benign ovarian Sex cord-stromal neoplasm",
          "benign ovarian Sex cord-stromal tumor",
          "benign ovarian Sex cord-stromal tumour",
          "ovarian SEX cord-stromal tumor, benign",
          "ovarian sex cord-stromal tumor, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A sex cord-stromal tumor arising from the ovary, without metastatic potential."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024387"
    },
    {
      "id": 22950,
      "label": "benign ovarian mucinous tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        5636,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:267038",
          "NCIT:C40039",
          "UMLS:C1511100"
        ],
        "synonyms": [
          "benign ovarian mucinous neoplasm",
          "benign ovarian mucinous tumor",
          "ovarian mucinous neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the ovary and is characterized by the presence of neoplastic epithelium that resembles the epithelium of the endocervix or gastrointestinal tract. It includes mucinous adenofibroma, mucinous cystadenofibroma, and mucinous cystadenoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0036915"
    }
  ],
  "roots": [
    {
      "id": 3029,
      "label": "benign female reproductive system neoplasm"
    },
    {
      "id": 20309,
      "label": "ovarian neoplasm"
    }
  ]
}