{
  "id": 3049,
  "label": "nervous system benign neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000648",
  "properties": {
    "xrefs": [
      "DOID:0060115",
      "ICD9:225.8",
      "ICD9:225.9",
      "MEDGEN:99232",
      "NCIT:C4789",
      "SCTID:92247009",
      "UMLS:C0497550"
    ],
    "synonyms": [
      "benign neoplasm of nervous system",
      "benign neoplasm of the nervous system",
      "benign nervous system neoplasm",
      "benign nervous system tumor",
      "benign nervous system tumour",
      "benign tumor of nervous system",
      "benign tumor of the nervous system",
      "benign tumour of nervous system",
      "benign tumour of the nervous system",
      "nervous system benign neoplasm",
      "nervous system neoplasm, benign"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Abnormal growth of cells in the nervous system without evidence of malignant characteristics. Unlike other organ systems, tumors in the central nervous system can have benign histological characteristics but still have life threatening effects due to their location within the neuraxis (e.g., brainstem gliomas)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6887,
      "label": "benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060072",
          "DOID:0060084",
          "DOID:0060085",
          "EFO:0002422",
          "ICD10CM:D10-D36",
          "ICD10WHO:D10-D36",
          "ICD9:210-229",
          "ICD9:229.8",
          "ICD9:229.9",
          "ICDO:8000/0",
          "MEDGEN:39483",
          "NCIT:C3677",
          "SCTID:20376005",
          "UMLS:C0086692"
        ],
        "synonyms": [
          "benign neoplasm",
          "benign neoplasm (disease)",
          "neoplasm (disease), benign",
          "benign tumor",
          "benign tumour",
          "benign unclassifiable tumor",
          "benign unclassifiable tumour",
          "cell type benign neoplasm",
          "neoplasm, benign",
          "organ system benign neoplasm"
        ],
        "definition": "A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites."
      },
      "child_count": 29,
      "reference_id": "MONDO:0005165"
    },
    {
      "id": 20456,
      "label": "nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:45046",
          "NCIT:C3268",
          "UMLS:C0027766"
        ],
        "synonyms": [
          "neoplasm of nervous system",
          "neoplasm of the nervous system",
          "nervous system neoplasm (disease)",
          "nervous system neoplasms",
          "nervous system tumor",
          "nervous system tumour",
          "tumor of nervous system",
          "tumor of the nervous system",
          "tumour of nervous system",
          "tumour of the nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the nervous system."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021248"
    }
  ],
  "children": [
    {
      "id": 3033,
      "label": "central nervous system organ benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3049,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060090",
          "MEDGEN:488882",
          "NCIT:C188049",
          "UMLS:C0347509"
        ],
        "synonyms": [
          "central nervous system benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the central nervous system."
      },
      "child_count": 26,
      "reference_id": "MONDO:0000628"
    },
    {
      "id": 3038,
      "label": "sensory organ benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060096"
        ],
        "synonyms": [
          "sense organ benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the sense organ."
      },
      "child_count": 10,
      "reference_id": "MONDO:0000633"
    },
    {
      "id": 10799,
      "label": "neurocutaneous melanocytosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3049,
        6801,
        23107,
        23867,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007186",
          "MEDGEN:154259",
          "MESH:C537387",
          "NANDO:2200827",
          "NCIT:C175215",
          "OMIM:249400",
          "Orphanet:2481",
          "UMLS:C0544862",
          "icd11.foundation:403221860"
        ],
        "synonyms": [
          "NCM",
          "neurocutaneous melanosis",
          "neurocutaneous melanosis, somatic",
          "NCMS",
          "Neuromelanosis",
          "melanosis, neurocutaneous",
          "neurocutaneous melanosis syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neurocutaneous melanocytosis (NCM) is a rare congenital neurological disorder characterized by abnormal aggregations of nevomelanocytes within the central nervous system (leptomeningeal melanocytosis) associated with large or giant congenital melanocytic nevi (CMN). NCM can be asymptomatic or present as variably severe and progressive neurological impairment, sometimes resulting in death."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009578"
    },
    {
      "id": 17196,
      "label": "hemangioblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3049,
        4497,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5241",
          "GARD:0008232",
          "ICDO:9161/1",
          "MEDGEN:104929",
          "MESH:D018325",
          "MedDRA:10018813",
          "NCIT:C3801",
          "ONCOTREE:HMBL",
          "Orphanet:252054",
          "UMLS:C0206734"
        ],
        "synonyms": [
          "angioblastoma",
          "capillary hemangioblastoma",
          "hemangioblastoma",
          "HMBL"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Hemangioblastoma is a rare, benign, highly vascularized tumor of the central nervous system, most often located in the cerebellum or spinal cord, presenting in adulthood and manifesting with dizziness, nausea, malaise, headache, bladder or bowel dysfunction, numbness, weakness and pain in the upper or lower extremities, and often associated with von Hippel-Lindau disease (VHL). Exceptional cases of hemangioblastoma arising outside of the central nervous system have been reported."
      },
      "child_count": 9,
      "reference_id": "MONDO:0016748"
    },
    {
      "id": 17636,
      "label": "phakomatosis pigmentokeratotica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3049,
        6801,
        19507,
        23107,
        23867,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004311",
          "MEDGEN:419860",
          "MESH:C537893",
          "Orphanet:2874",
          "SCTID:723455009",
          "UMLS:C2931658",
          "icd11.foundation:960559196"
        ],
        "synonyms": [
          "Phacomatosis pigmentokeratotica",
          "organoid nevus with sebaceous differentiation, a speckled-lentiginous nevus, and other associated anomalies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Phakomatosis pigmentokeratotica (PPK) is a very rare epidermal nevus disorder characterized by the association of speckled lentiginous nevi with epidermal sebaceous nevi, and extracutaneous anomalies."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017317"
    }
  ],
  "roots": [
    {
      "id": 6887,
      "label": "benign neoplasm"
    },
    {
      "id": 20456,
      "label": "nervous system neoplasm"
    }
  ]
}