{
  "id": 3133,
  "label": "allergic respiratory disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000771",
  "properties": {
    "xrefs": [
      "DOID:0060496",
      "MEDGEN:734246",
      "UMLS:C1504369"
    ],
    "synonyms": [
      "allergic form of respiratory system disease",
      "allergic respiratory system disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A respiratory system disease with a basis in a pathological type I hypersensitivity reaction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6815,
      "label": "respiratory system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1579",
          "EFO:0000684",
          "ICD10CM:J00-J99",
          "ICD9:460-519",
          "ICD9:500-508",
          "ICD9:503",
          "ICD9:508",
          "ICD9:508.1",
          "ICD9:508.8",
          "ICD9:508.9",
          "ICD9:510-519",
          "ICD9:516",
          "ICD9:516.8",
          "ICD9:516.9",
          "ICD9:517",
          "ICD9:517.8",
          "ICD9:519",
          "ICD9:519.1",
          "ICD9:519.3",
          "ICD9:519.8",
          "ICD9:519.9",
          "ICD9:V12.60",
          "ICD9:V47.2",
          "MEDGEN:48421",
          "MESH:D012140",
          "NANDO:1100010",
          "NCIT:C26871",
          "SCTID:50043002",
          "UMLS:C0035204"
        ],
        "synonyms": [
          "disease of respiratory system",
          "disease or disorder of respiratory system",
          "disorder of respiratory system",
          "respiratory disease",
          "respiratory disorder",
          "respiratory system disease",
          "respiratory system disease or disorder",
          "respiratory system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma."
      },
      "child_count": 59,
      "reference_id": "MONDO:0005087"
    },
    {
      "id": 6969,
      "label": "allergic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3018
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1205",
          "ICD9:995.3",
          "ICD9:V15.09",
          "MEDGEN:9370",
          "MESH:D006967",
          "NCIT:C114476",
          "SCTID:609328004",
          "UMLS:C0020517"
        ],
        "synonyms": [
          "allergic disease or disorder",
          "allergic form of disease or disorder",
          "allergic form of immune system disease",
          "allergic reaction",
          "allergic response",
          "allergy",
          "disorder of type I hypersensitivity",
          "type I hypersensitivity disease",
          "allergic hypersensitivity disease",
          "hypersensitivity"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An immune response that occurs following re-exposure to an innocuous antigen, and that requires the presence of existing antibodies against that antigen. This response involves the binding of IgE to mast cells, and may worsen with repeated exposures."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005271"
    }
  ],
  "children": [
    {
      "id": 6551,
      "label": "allergic asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9415",
          "ICD9:493.0",
          "MEDGEN:102343",
          "SCTID:389145006",
          "UMLS:C0155877",
          "icd11.foundation:1870104478"
        ],
        "synonyms": [
          "allergic form of asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A asthma with a basis in a pathological type I hypersensitivity reaction."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004784"
    },
    {
      "id": 12870,
      "label": "allergic rhinitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        5011
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4481",
          "EFO:0005854",
          "HP:0003193",
          "ICD9:477",
          "ICD9:477.8",
          "ICD9:477.9",
          "MEDGEN:382012",
          "NCIT:C79532",
          "SCTID:61582004",
          "UMLS:C2607914",
          "icd11.foundation:1711769234"
        ],
        "synonyms": [
          "allergic form of rhinitis",
          "allergic rhinitis",
          "Perenial allergic rhinitis",
          "atopic rhinitis",
          "non-seasonal allergic rhinitis",
          "perennial allergic rhinitis",
          "seasonal allergic rhinitis",
          "Alrh"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life."
      },
      "child_count": 6,
      "reference_id": "MONDO:0011786"
    },
    {
      "id": 16132,
      "label": "allergic bronchopulmonary aspergillosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        7292
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13166",
          "EFO:0007140",
          "GARD:0000602",
          "ICD10CM:B44.81",
          "ICD9:518.6",
          "MEDGEN:479932",
          "MESH:D001229",
          "MedDRA:10006474",
          "NCIT:C84547",
          "OMIM:103920",
          "Orphanet:1164",
          "SCTID:37981002",
          "UMLS:C3278302",
          "icd11.foundation:1591607082"
        ],
        "synonyms": [
          "ABPA",
          "Hinson-Pepys disease",
          "allergic aspergillosis",
          "allergic bronchopulmonary aspergillosis, familial",
          "allergic bronchopulmonary mycosis",
          "aspergillosis, allergic bronchopulmonary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Allergic bronchopulmonary aspergillosis (ABPA) is a rare immunologic pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus, clinically manifesting with poorly controlled asthma and recurrent pulmonary infiltrates."
      },
      "child_count": 2,
      "reference_id": "MONDO:0015243"
    },
    {
      "id": 18069,
      "label": "hypersensitivity pneumonitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        16615,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:841",
          "GARD:0000012",
          "ICD9:495",
          "ICD9:495.8",
          "ICD9:495.9",
          "MEDGEN:1446",
          "MESH:D000542",
          "MedDRA:10001890",
          "NCIT:C34369",
          "NORD:761",
          "Orphanet:31740",
          "SCTID:37471005",
          "UMLS:C0002390"
        ],
        "synonyms": [
          "HP",
          "allergic form of pneumonitis",
          "allergic pneumonitis",
          "exogen allergic alveolitis",
          "extrinsic allergic alveolitis",
          "hypersensitivity pneumonitis",
          "allergic interstitial pneumonitis",
          "alveolitis, extrinsic allergic",
          "extrinsic allergic pneumonia hypersensitivity pneumonitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Hypersensitivity pneumonitis (HP) is a pulmonary disease with symptoms of dyspnea and cough resulting from the inhalation of an antigen to which the subject has been previously sensitized."
      },
      "child_count": 42,
      "reference_id": "MONDO:0017853"
    }
  ],
  "roots": [
    {
      "id": 6815,
      "label": "respiratory system disorder"
    },
    {
      "id": 6969,
      "label": "allergic disease"
    }
  ]
}