{
  "id": 3138,
  "label": "purpura fulminans",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000809",
  "properties": {
    "xrefs": [
      "DOID:0060538",
      "GARD:0022830",
      "MEDGEN:88448",
      "MESH:D055665",
      "SCTID:13507004",
      "UMLS:C0085650",
      "icd11.foundation:1293848111"
    ],
    "synonyms": [
      "fibrinolytic purpura"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by disseminated intravascular coagulation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3483,
      "label": "disseminated intravascular coagulation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4413
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11247",
          "GARD:0022908",
          "ICD10CM:D65",
          "ICD9:286.6",
          "MEDGEN:41620",
          "MESH:D004211",
          "NANDO:2200639",
          "NCIT:C2992",
          "SCTID:67406007",
          "UMLS:C0012739",
          "icd11.foundation:1622289887"
        ],
        "synonyms": [
          "DIC",
          "DIC, disseminated intravascular coagulation",
          "coagulation (DIC), disseminated intravascular",
          "consumptive coagulopathy",
          "defibrination syndrome",
          "diffuse or disseminated intravascular coagulation",
          "disseminated intravascular coagulation",
          "disseminated intravascular coagulation (DIC)",
          "intravascular coagulation (DIC), disseminated"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A pathological process where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, and there is an increased risk of hemorrhage."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001243"
    },
    {
      "id": 4662,
      "label": "purpura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3326",
          "HP:0000979",
          "MEDGEN:19584",
          "MESH:D011693",
          "SCTID:387778001",
          "UMLS:C0034150"
        ],
        "synonyms": [
          "purpura",
          "purpura (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A small blood vessel hemorrhage into the skin and/or mucous membranes. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002610"
    }
  ],
  "children": [
    {
      "id": 18790,
      "label": "acquired purpura fulminans",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3138,
        3150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018838",
          "MEDGEN:1377273",
          "MedDRA:10037556",
          "Orphanet:49566",
          "SCTID:725157006",
          "UMLS:C4510896"
        ],
        "synonyms": [
          "acquired PF",
          "acquired purpura fulminans"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of PF that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic PF."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018854"
    }
  ],
  "roots": [
    {
      "id": 3483,
      "label": "disseminated intravascular coagulation"
    },
    {
      "id": 4662,
      "label": "purpura"
    }
  ]
}