{
  "id": 3149,
  "label": "juvenile-onset Parkinson disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000828",
  "properties": {
    "xrefs": [
      "DOID:0060893",
      "GARD:0022833",
      "MEDGEN:155699",
      "UMLS:C0752105"
    ],
    "synonyms": [
      "juvenile-onset Parkinson's disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 17603,
      "label": "young-onset Parkinson disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6901
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060894",
          "GARD:0016610",
          "MEDGEN:907947",
          "Orphanet:2828",
          "SCTID:715345007",
          "UMLS:C4275179"
        ],
        "synonyms": [
          "YOPD",
          "early-onset Parkinson disease",
          "early-onset Parkinson's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of Parkinson disease (PD) characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most YOPD forms."
      },
      "child_count": 9,
      "reference_id": "MONDO:0017279"
    }
  ],
  "children": [
    {
      "id": 12794,
      "label": "Kufor-Rakeb syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3149,
        18404
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060556",
          "GARD:0009174",
          "MEDGEN:338281",
          "MESH:C537177",
          "NORD:1959",
          "OMIM:606693",
          "Orphanet:306674",
          "UMLS:C1847640"
        ],
        "synonyms": [
          "Kufor Rakeb Syndrome",
          "Kufor-Rakeb syndrome",
          "PARK9",
          "KRPPD",
          "KRS",
          "Pallidopyramidal Degeneration with supranuclear upgaze paresis and dementia",
          "Pallidopyramidal degeneration with supranuclear upgaze paresis, and dementia",
          "Parkinson disease 9, autosomal recessive",
          "Parkinson disease 9, autosomal recessive, juvenile-onset",
          "Parkinson disease type 9",
          "ceroid lipofuscinosis, neuronal, 12",
          "park 9"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Kufor-Rakeb syndrome (KRS) is a rare genetic neurodegenerative disorder characterized by juvenile Parkinsonism, pyramidal degeneration (dystonia), supranuclear palsy, and cognitive impairment."
      },
      "child_count": 2,
      "reference_id": "MONDO:0011706"
    },
    {
      "id": 15237,
      "label": "juvenile onset Parkinson disease 19A",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3149,
        18416
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060891",
          "GARD:0018461",
          "MEDGEN:816141",
          "OMIM:615528",
          "UMLS:C3809811"
        ],
        "synonyms": [
          "DNAJC6 Parkinson disease",
          "Parkinson disease caused by mutation in DNAJC6",
          "juvenile onset Parkinson disease 19A",
          "juvenile onset Parkinson disease type 19A",
          "PARK19",
          "PARK19A",
          "Park19, formerly",
          "Parkinson disease 19, juvenile-onset",
          "Parkinson disease 19A, juvenile-onset",
          "Parkinson disease 19B, early-onset",
          "juvenile onset Parkinson's disease 19A"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any Parkinson disease in which the cause of the disease is a mutation in the DNAJC6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014231"
    },
    {
      "id": 24958,
      "label": "Parkinson disease 19B, early-onset",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026528",
          "MEDGEN:934769",
          "UMLS:C4310802"
        ],
        "synonyms": [
          "PARK19B"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0800369"
    }
  ],
  "roots": [
    {
      "id": 17603,
      "label": "young-onset Parkinson disease"
    }
  ]
}