{
  "id": 3150,
  "label": "thrombotic disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000831",
  "properties": {
    "xrefs": [
      "DOID:0060903",
      "ICD9:453.9",
      "MEDGEN:21160",
      "MESH:D013927",
      "NCIT:C26891",
      "SCTID:439127006",
      "UMLS:C0040053"
    ],
    "synonyms": [
      "Clots, blood",
      "Thromboses",
      "blood Clots",
      "blood clot",
      "clot, blood",
      "thrombosis",
      "thrombotic disorder",
      "thrombus"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "The formation of a blood clot in the lumen of a vessel or heart chamber; causes include coagulation disorders and vascular endothelial injury."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 3021,
      "label": "marantic endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        3738,
        6759
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060068",
          "GARD:0022812",
          "MEDGEN:452215",
          "MESH:D059905",
          "SCTID:57181007",
          "UMLS:C0221390"
        ],
        "synonyms": [
          "nonbacterial thrombotic endocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Formation of a non-infectious thrombus, referred to as vegetation, on previously undamaged endocardium. It usually occurs as a complication of connective-tissue diseases and cancers because of the associated hypercoagulable state (see thrombophilia)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000610"
    },
    {
      "id": 3567,
      "label": "portal vein thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        4495,
        6420
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11695",
          "ICD10CM:I81",
          "ICD10WHO:I81",
          "ICD9:452",
          "MEDGEN:56372",
          "NCIT:C78565",
          "SCTID:17920008",
          "UMLS:C0155773",
          "icd11.foundation:866276949"
        ],
        "synonyms": [
          "portal vein thrombotic disease",
          "thrombotic disease of portal vein"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "The formation of a blood clot (thrombus) in the portal vein."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001339"
    },
    {
      "id": 4914,
      "label": "intracranial thrombosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3150,
        12183
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4193",
          "ICD9:434.0",
          "ICD9:434.00",
          "MEDGEN:199820",
          "MESH:D020767",
          "SCTID:71444005",
          "UMLS:C0752143"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Formation or presence of a blood clot (thrombus) in a blood vessel within the skull. Intracranial thrombosis can lead to thrombotic occlusions and brain infarction. The majority of the thrombotic occlusions are associated with atherosclerosis."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002907"
    },
    {
      "id": 8177,
      "label": "coronary thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11847",
          "EFO:1000883",
          "ICD10CM:I22",
          "MEDGEN:3625",
          "MESH:D003328",
          "MedDRA:10011108",
          "SCTID:398274000",
          "UMLS:C0010072"
        ],
        "synonyms": [
          "coronary vessel thrombotic disease",
          "thrombotic disease of coronary vessel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006716"
    },
    {
      "id": 18214,
      "label": "heparin-induced thrombocytopenia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002650",
          "HP:0011874",
          "ICD9:289.84",
          "MEDGEN:124423",
          "MedDRA:10062506",
          "NANDO:2200648",
          "Orphanet:3325",
          "SCTID:73397007",
          "UMLS:C0272285",
          "icd11.foundation:1143142333"
        ],
        "synonyms": [
          "HAT",
          "HIT",
          "heparin-associated thrombocytopenia",
          "heparin-induced thrombocytopenia",
          "heparin-induced thrombocytopenia (disease)",
          "heparin-induced thrombocytopenia type 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Heparin-induced thrombocytopenia (HIT) is a drug-induced, immune-mediated prothrombotic disorder associated with thrombocytopenia and venous and/or arterial thrombosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018048"
    },
    {
      "id": 18790,
      "label": "acquired purpura fulminans",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3138,
        3150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018838",
          "MEDGEN:1377273",
          "MedDRA:10037556",
          "Orphanet:49566",
          "SCTID:725157006",
          "UMLS:C4510896"
        ],
        "synonyms": [
          "acquired PF",
          "acquired purpura fulminans"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of PF that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic PF."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018854"
    },
    {
      "id": 22795,
      "label": "isolated splenic vein thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        6420
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022338",
          "MEDGEN:544034",
          "Orphanet:583856",
          "UMLS:C0272416",
          "icd11.foundation:121618859"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035008"
    },
    {
      "id": 22796,
      "label": "isolated mesenteric vein thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        6420,
        6756
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022339",
          "MEDGEN:120599",
          "Orphanet:583861",
          "UMLS:C0267412",
          "icd11.foundation:213868120"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035009"
    }
  ],
  "roots": [
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}