{
  "id": 3155,
  "label": "fibrous dysplasia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000845",
  "properties": {
    "xrefs": [
      "DOID:0080031",
      "GARD:0006444",
      "ICD9:733.29",
      "MEDGEN:120444",
      "MESH:D005357",
      "MedDRA:10016664",
      "NCIT:C34609",
      "NORD:1147",
      "Orphanet:249",
      "SCTID:10623005",
      "SCTID:254145001",
      "UMLS:C0259779",
      "icd11.foundation:1704766818"
    ],
    "synonyms": [
      "fibrous dysplasia of bone"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "A genetic, non-inheritable disorder caused by osteoblastic differentiation defects that result in the replacement of bone marrow and trabecular bone by fibrous stroma and immature bone. It usually affects a single bone and less frequently multiple bones. Skull, femur, tibia, and humerus are the most frequently affected bones. It manifests with pain, deformities, and fractures."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3151,
      "label": "bone remodeling disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080005"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A bone disease that results in formation or resorption abnormalities located in bone."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000833"
    }
  ],
  "children": [
    {
      "id": 9581,
      "label": "polyostotic fibrous dysplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3155
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004213",
          "ICD10CM:Q78.1",
          "ICD9:756.54",
          "MEDGEN:5180",
          "MESH:D005359",
          "MedDRA:10036120",
          "NCIT:C34610",
          "Orphanet:93276",
          "SCTID:36517007",
          "UMLS:C0016065",
          "icd11.foundation:771587091"
        ],
        "synonyms": [
          "fibrous dysplasia of bone",
          "PFD",
          "polyostotic fibrous dysplasia of bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Fibrous dysplasia affecting more than one bone. When it is associated with café-au-lait skin pigmentation and endocrine disorders, it is known as McCune-Albright syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008274"
    },
    {
      "id": 19451,
      "label": "monostotic fibrous dysplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3155
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019181",
          "HP:0010736",
          "ICD9:733.29",
          "MEDGEN:42020",
          "MESH:D005358",
          "NCIT:C53971",
          "Orphanet:93277",
          "SCTID:89859004",
          "UMLS:C0016064",
          "icd11.foundation:1033883899"
        ],
        "synonyms": [
          "Jaffe-Lichtenstein disease",
          "monostotic fibrous dysplasia",
          "monostotic fibrous dysplasia (disease)",
          "monostotic fibrous dysplasia of bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Fibrous dysplasia of bone involving only one bone."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019665"
    },
    {
      "id": 23149,
      "label": "panostotic fibrous dysplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3155,
        10906
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025857",
          "MEDGEN:419799",
          "MESH:C537164",
          "UMLS:C2931430"
        ],
        "synonyms": [
          "unusual facial appearance, bone fragility, hyperphosphatasemia, and hypophosphatemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0043168"
    }
  ],
  "roots": [
    {
      "id": 3151,
      "label": "bone remodeling disease"
    }
  ]
}