{
  "id": 3201,
  "label": "endometrial disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000931",
  "properties": {
    "xrefs": [
      "DOID:1005",
      "MEDGEN:57473",
      "NCIT:C3504",
      "SCTID:418632009",
      "UMLS:C0151622"
    ],
    "synonyms": [
      "disease of endometrium",
      "disease or disorder of endometrium",
      "disorder of endometrium",
      "endometrial disorder",
      "endometrium disease",
      "endometrium disease or disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder that affects the endometrium. Representative examples include endometritis, endometrial hyperplasia, and endometrial carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4705,
      "label": "uterine disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:345",
          "ICD9:621.8",
          "ICD9:621.9",
          "MEDGEN:22590",
          "MESH:D014591",
          "NCIT:C26907",
          "SCTID:12337004",
          "UMLS:C0042131"
        ],
        "synonyms": [
          "disease of uterus",
          "disease or disorder of uterus",
          "disorder of uterus",
          "uterine disease",
          "uterine disorder",
          "uterus disease",
          "uterus disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the uterine corpus or the cervix. Representative examples of non-neoplastic disorders include endometritis and cervicitis. Representative examples of neoplastic disorders include endometrial carcinoma, carcinosarcoma, and cervical carcinoma."
      },
      "child_count": 21,
      "reference_id": "MONDO:0002654"
    }
  ],
  "children": [
    {
      "id": 3188,
      "label": "endometritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3201,
        20016
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1002",
          "EFO:1001312",
          "MEDGEN:41789",
          "MESH:D004716",
          "NCIT:C26764",
          "SCTID:78623009",
          "UMLS:C0014179"
        ],
        "synonyms": [
          "endometrium inflammation",
          "inflammation of endometrium",
          "uterine infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An acute or chronic, usually bacterial infectious process affecting the endometrium. It may extend to the myometrium and parametrial tissues. Symptoms include lower abdominal pain, vaginal discharge, and vaginal bleeding."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000918"
    },
    {
      "id": 6223,
      "label": "tamoxifen-related endometrial lesion",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7962",
          "MEDGEN:271571",
          "NCIT:C40159",
          "UMLS:C1515212"
        ],
        "synonyms": [
          "tamoxifen-related endometrial disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A spectrum of endometrial abnormalities that occur in women who use tamoxifen to treat or prevent the development of breast cancer. These abnormalities include endometrial polyps, endometrial hyperplasia, and endometrial carcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004414"
    },
    {
      "id": 6857,
      "label": "endometriosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:289",
          "EFO:0001065",
          "HP:0030127",
          "ICD10CM:N80",
          "ICD10WHO:N80",
          "ICD9:617",
          "ICD9:617.8",
          "ICD9:617.9",
          "MEDGEN:8620",
          "MESH:D004715",
          "NCIT:C3014",
          "SCTID:129103003",
          "UMLS:C0014175",
          "icd11.foundation:1838213761"
        ],
        "synonyms": [
          "endometriosis",
          "endometriosis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs."
      },
      "child_count": 7,
      "reference_id": "MONDO:0005133"
    },
    {
      "id": 7670,
      "label": "atypical endometrial hyperplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3201,
        6775
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000098",
          "ICD9:621.33",
          "MEDGEN:138105",
          "NCIT:C4654",
          "SCTID:277158007",
          "UMLS:C0349579"
        ],
        "synonyms": [
          "atypical hyperplasia of endometrium",
          "atypical hyperplasia of the endometrium",
          "endometrial hyperplasia with atypia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An endometrial hyperplasia characterized by cytologic and architectural changes which may lead to endometrial carcinoma. Despite the atypical features and possible course, there is debate on whether to consider this a neoplasm. The relationship with endometrial intraepithelial neoplasia is also unclear."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006096"
    },
    {
      "id": 7750,
      "label": "endometrial polyp",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3201,
        6481
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000237",
          "MEDGEN:312370",
          "NCIT:C6433",
          "UMLS:C1704273"
        ],
        "synonyms": [
          "endometrial polyp",
          "endometrial stromal polyp",
          "endometrium polyp",
          "polyp of endometrium",
          "polyp of the endometrium",
          "polyp, endometrial stromal, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign nodular lesion protruding above the surface of the endometrium. It is composed of a fibrous stroma that contains thick-walled blood vessels and dilated endometrial glands. Polypectomy is the treatment of choice. Only few cases with recurrence have been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006195"
    },
    {
      "id": 12022,
      "label": "adenomyosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:288",
          "ICD10CM:N80.0",
          "ICD9:617.0",
          "MEDGEN:1805484",
          "MESH:D062788",
          "NCIT:C6996",
          "OMIM:600458",
          "SCTID:237115002",
          "UMLS:C5574708",
          "icd11.foundation:171294592"
        ],
        "synonyms": [
          "adenomyosis of the uterus",
          "adenomyosis of uterus",
          "endometriosis (disease) of myometrium",
          "endometriosis interna",
          "endometriosis of myometrium",
          "endometriosis of uterus",
          "endometriosis, myometrium",
          "myometrium endometriosis (disease)",
          "uterine adenomyosis",
          "uterine corpus adenomyosis",
          "uterus corpus adenomyosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "The growth of endometrial tissue inside the muscular wall of the uterine corpus. Clinical manifestations include pain, dysmenorrhea, and menorrhagia."
      },
      "child_count": 1,
      "reference_id": "MONDO:0010888"
    },
    {
      "id": 20459,
      "label": "endometrium neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3201,
        20520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.5",
          "MEDGEN:8619",
          "MESH:D016889",
          "NCIT:C3012",
          "SCTID:123844007",
          "UMLS:C0014170"
        ],
        "synonyms": [
          "endometrial neoplasm",
          "endometrial tumor",
          "endometrial tumour",
          "endometrium neoplasm (disease)",
          "endometrium tumor",
          "endometrium tumour",
          "neoplasm of endometrium",
          "neoplasm of the endometrium",
          "tumor of endometrium",
          "tumor of the endometrium",
          "tumour of endometrium",
          "tumour of the endometrium"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the endometrium."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021251"
    }
  ],
  "roots": [
    {
      "id": 4705,
      "label": "uterine disorder"
    }
  ]
}