{
  "id": 3347,
  "label": "mediastinum neuroblastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001095",
  "properties": {
    "xrefs": [
      "DOID:10660",
      "EFO:1000367",
      "GARD:0022879",
      "MEDGEN:235313",
      "NCIT:C6628",
      "UMLS:C1334673"
    ],
    "synonyms": [
      "mediastinum neuroblastoma",
      "neuroblastoma of mediastinum",
      "mediastinal neuroblastoma",
      "neuroblastoma of the mediastinum"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A neuroblastoma arising from the mediastinum."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5083,
      "label": "mediastinal neural neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3627,
        20542
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4691",
          "MEDGEN:277353",
          "NCIT:C6624",
          "UMLS:C1334672"
        ],
        "synonyms": [
          "mediastinal neural neoplasm",
          "mediastinal neural tumor",
          "mediastinal neural tumour",
          "mediastinal neurogenic neoplasm",
          "mediastinal neurogenic tumor",
          "mediastinal neurogenic tumour",
          "neurogenic neoplasm of mediastinum",
          "neurogenic neoplasm of the mediastinum",
          "neurogenic tumor of mediastinum",
          "neurogenic tumor of the mediastinum",
          "neurogenic tumour of mediastinum",
          "neurogenic tumour of the mediastinum",
          "malignant mediastinal neurogenic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neurogenic tumor that arises from the mediastinum. Neural tumors are the most common tumors that arise from the posterior mediastinum. Representative examples include Schwannoma, neurofibroma, and neuroblastoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0003098"
    },
    {
      "id": 6800,
      "label": "neuroblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7851,
        20691
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:769",
          "EFO:0000621",
          "GARD:0007185",
          "ICDO:9500/3",
          "MEDGEN:18012",
          "MESH:D009447",
          "MedDRA:10029260",
          "NANDO:2200040",
          "NCIT:C3270",
          "ONCOTREE:NBL",
          "Orphanet:635",
          "SCTID:432328008",
          "UMLS:C0027819",
          "birnlex:12631"
        ],
        "synonyms": [
          "neural Crest tumor, malignant",
          "neuroblastoma",
          "neuroblastoma (Schwannian Stroma-poor)",
          "neuroblastoma, malignant",
          "NB"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neuroblastoma (NB) is the most common solid, extracranial childhood tumor. It is an aggressive pediatric cancer that originates from neural crest tissues of the sympathetic nervous system."
      },
      "child_count": 14,
      "reference_id": "MONDO:0005072"
    },
    {
      "id": 7455,
      "label": "mediastinal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5215,
        20542
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5559",
          "EFO:0007362",
          "ICD9:164.9",
          "MEDGEN:56308",
          "MESH:D008479",
          "NCIT:C3549",
          "SCTID:363494000",
          "UMLS:C0153504"
        ],
        "synonyms": [
          "mediastinal tumor",
          "mediastinal tumour",
          "tumor of mediastinum",
          "tumour of mediastinum",
          "cancer of mediastinum",
          "cancer of the mediastinum",
          "malignant mediastinal neoplasm",
          "malignant mediastinal tumor",
          "malignant mediastinal tumour",
          "malignant mediastinum neoplasm",
          "malignant neoplasm of mediastinum",
          "malignant neoplasm of the mediastinum",
          "malignant tumor of mediastinum",
          "malignant tumor of the mediastinum",
          "malignant tumour of mediastinum",
          "malignant tumour of the mediastinum",
          "mediastinal cancer",
          "mediastinum cancer"
        ],
        "definition": "A malignant neoplasm involving the mediastinum"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005843"
    },
    {
      "id": 20329,
      "label": "peripheral nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3627,
        7479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:171.9",
          "MEDGEN:155556",
          "NCIT:C4961",
          "SCTID:254986007",
          "UMLS:C0751428"
        ],
        "synonyms": [
          "cancer of peripheral nervous system",
          "malignant PNS neoplasm",
          "malignant PNS tumor",
          "malignant PNS tumour",
          "malignant neoplasm of PNS",
          "malignant neoplasm of peripheral nerve",
          "malignant neoplasm of peripheral nervous system",
          "malignant neoplasm of the PNS",
          "malignant neoplasm of the peripheral nerve",
          "malignant neoplasm of the peripheral nervous system",
          "malignant neoplasms, peripheral nerve",
          "malignant peripheral nerve neoplasm",
          "malignant peripheral nerve tumor",
          "malignant peripheral nerve tumour",
          "malignant peripheral nervous system neoplasm",
          "malignant peripheral nervous system tumor",
          "malignant peripheral nervous system tumour",
          "malignant tumor of PNS",
          "malignant tumor of peripheral nerve",
          "malignant tumor of peripheral nervous system",
          "malignant tumor of the PNS",
          "malignant tumor of the peripheral nerve",
          "malignant tumor of the peripheral nervous system",
          "malignant tumour of PNS",
          "malignant tumour of peripheral nerve",
          "malignant tumour of peripheral nervous system",
          "malignant tumour of the PNS",
          "malignant tumour of the peripheral nerve",
          "malignant tumour of the peripheral nervous system",
          "peripheral nervous system cancer",
          "peripheral nervous system neoplasms, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Malignant growth of cells in the peripheral nervous system (PNS)or Autonomic Nervous System (ANS), without specification as to location"
      },
      "child_count": 36,
      "reference_id": "MONDO:0021089"
    }
  ],
  "children": [
    {
      "id": 3348,
      "label": "mediastinum ganglioneuroblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3347,
        5265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10661",
          "GARD:0022880",
          "MEDGEN:235308",
          "NCIT:C6627",
          "UMLS:C1334653"
        ],
        "synonyms": [
          "ganglioneuroblastoma (disease) of mediastinum",
          "ganglioneuroblastoma of mediastinum",
          "ganglioneuroblastoma of the mediastinum",
          "mediastinal ganglioneuroblastoma",
          "mediastinum ganglioneuroblastoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A ganglioneuroblastoma arising from the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001096"
    }
  ],
  "roots": [
    {
      "id": 5083,
      "label": "mediastinal neural neoplasm"
    },
    {
      "id": 6800,
      "label": "neuroblastoma"
    },
    {
      "id": 7455,
      "label": "mediastinal cancer"
    },
    {
      "id": 20329,
      "label": "peripheral nervous system cancer"
    }
  ]
}