{
  "id": 3387,
  "label": "salivary gland disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001142",
  "properties": {
    "xrefs": [
      "DOID:10854",
      "EFO:0008581",
      "ICD9:527.8",
      "ICD9:527.9",
      "MEDGEN:892384",
      "MESH:D012466",
      "NCIT:C26879",
      "SCTID:10890000",
      "UMLS:C0149772",
      "icd11.foundation:1432273670"
    ],
    "synonyms": [
      "disease of saliva-secreting gland",
      "disease or disorder of saliva-secreting gland",
      "disorder of saliva-secreting gland",
      "saliva-secreting gland disease",
      "saliva-secreting gland disease or disorder",
      "salivary gland disease",
      "salivary gland disorder",
      "non-neoplastic salivary gland disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "A disease involving the saliva-secreting gland."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 8301,
      "label": "mouth disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:403",
          "EFO:1001047",
          "ICD9:528.9",
          "MEDGEN:6448",
          "MESH:D009059",
          "NCIT:C3240",
          "SCTID:118938008",
          "UMLS:C0026636"
        ],
        "synonyms": [
          "disease of mouth",
          "disease or disorder of mouth",
          "disorder of mouth",
          "mouth disease",
          "mouth disease or disorder",
          "oral disease",
          "oral disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the mouth."
      },
      "child_count": 27,
      "reference_id": "MONDO:0006858"
    }
  ],
  "children": [
    {
      "id": 3796,
      "label": "submandibular gland disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12897",
          "MEDGEN:52535",
          "MESH:D013364",
          "UMLS:C0038557"
        ],
        "synonyms": [
          "disease of submandibular gland",
          "disease or disorder of submandibular gland",
          "disorder of submandibular gland",
          "submandibular gland disease",
          "submandibular gland disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the submandibular gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001597"
    },
    {
      "id": 3797,
      "label": "benign lymphoepithelial lesion of salivary gland",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3002,
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12899",
          "ICD9:527.8",
          "MEDGEN:120595",
          "NCIT:C3949",
          "SCTID:45517002",
          "UMLS:C0266995",
          "icd11.foundation:1330363110"
        ],
        "synonyms": [
          "Godwin tumor",
          "Godwin tumour",
          "benign lymphoepithelial lesion of salivary gland",
          "benign lymphoepithelial lesion of the salivary gland",
          "benign salivary gland lymphoepithelial lesion"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A benign lesion that involves the salivary glands, usually the parotid gland. It affects females more often than males and it may be a manifestation of autoimmune diseases such as Sjogren syndrome. There is an increased incidence of benign lymphoepithelial lesions in HIV-positive patients. It is characterized by the presence of a marked lymphocytic infiltrate and epi-myoepithelial islands in the affected salivary gland. Patients usually present with firm and painless swelling of the affected salivary gland. There is an increased risk for development of lymphoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001598"
    },
    {
      "id": 3798,
      "label": "mucocele of salivary gland",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12904",
          "ICD10CM:K11.6",
          "ICD9:527.6",
          "MEDGEN:10117",
          "MESH:D011900",
          "SCTID:69825009",
          "UMLS:C0026686",
          "icd11.foundation:48444833"
        ],
        "synonyms": [
          "mucous retention cyst of salivary gland",
          "ranula",
          "salivary cyst",
          "salivary gland mucocele"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A benign cyst located in the salivary gland that is lined by epithelium and filled with mucoid fluid, tissue, or other material; it is usually caused by duct obstruction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001600"
    },
    {
      "id": 7502,
      "label": "parotid disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10302",
          "EFO:0007422",
          "MEDGEN:10593",
          "MESH:D010305",
          "UMLS:C0030579"
        ],
        "synonyms": [
          "disease of parotid gland",
          "disease or disorder of parotid gland",
          "disorder of parotid gland",
          "parotid gland disease",
          "parotid gland disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the parotid gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005899"
    },
    {
      "id": 8306,
      "label": "necrotizing sialometaplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12901",
          "ICD9:527.8",
          "MEDGEN:48659",
          "MESH:D012797",
          "MedDRA:10072176",
          "SCTID:109769000",
          "UMLS:C0037033"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A benign, inflammatory, variably ulcerated, occasionally bilateral, self-healing lesion of the minor salivary glands that is often confused clinically and histologically with carcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006864"
    },
    {
      "id": 8394,
      "label": "sialadenitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3387,
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10303",
          "EFO:1001179",
          "ICD10CM:K11.2",
          "ICD9:527.2",
          "MEDGEN:48657",
          "MESH:D012793",
          "MedDRA:10040627",
          "NCIT:C115165",
          "NCIT:C26882",
          "SCTID:42982001",
          "UMLS:C0037023"
        ],
        "synonyms": [
          "lymphadenitis (disease) of saliva-secreting gland",
          "saliva-secreting gland lymphadenitis (disease)",
          "sialitis",
          "sialoadenitis",
          "adenitis, salivary gland",
          "salivary gland inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Sialadenitis is an infection of the salivary glands. It is usually caused by a virus or bacteria. The parotid (in front ofthe ear) and submandibular (under the chin) glands are most commonly affected. Sialadenitis may be associated with pain, tenderness, redness, and gradual, localized swelling of the affected area. Sialadenitis most commonly affects the elderly and chronically ill especially those with dry mouth or who are dehydrated, but can also affected people of any age including newborn babies. Diagnosis is usually made by clinical exam but a CT scan, MRI scan or ultrasound may be done if the doctor suspects an abscess or to look for stones. Treatment may include an antibiotic (if bacterial), warm compresses, increasing fluid intake and good oral hygiene. Most salivary gland infections go away on their own or are cured with treatment. Complications are not common."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006969"
    },
    {
      "id": 8395,
      "label": "sialolithiasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12905",
          "EFO:1001180",
          "ICD10CM:K11.5",
          "ICD9:527.5",
          "MEDGEN:48536",
          "MESH:D015494",
          "MedDRA:10040631",
          "SCTID:28826002",
          "UMLS:C0036091",
          "icd11.foundation:1984849248"
        ],
        "synonyms": [
          "Stone of salivary gland or duct",
          "sialolith"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A concretion in the salivary gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006970"
    },
    {
      "id": 11224,
      "label": "Sjogren syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3002,
        3387,
        4370,
        21539
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12894",
          "EFO:0000699",
          "ICD10CM:M35.0",
          "ICD9:710.2",
          "MEDGEN:282890",
          "MESH:D012859",
          "NANDO:1200279",
          "NANDO:1200280",
          "NANDO:2200420",
          "NCIT:C26883",
          "OMIM:270150",
          "Orphanet:289390",
          "Orphanet:378",
          "SCTID:83901003",
          "UMLS:C1527336",
          "icd11.foundation:899463360"
        ],
        "synonyms": [
          "Sjogren syndrome",
          "Sjögren syndrome",
          "Sjögren-Gougerot syndrome",
          "primary Sjogren-Gougerot syndrome",
          "primary Sjögren-Gougerot syndrome",
          "sicca syndrome",
          "syndrome, Sjogren's",
          "Sjogren's syndrome",
          "primary Sjögren syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. Sjögren syndrome is also associated with rheumatic disorders such as rheumatoid arthritis or systemic lupus erythematosus. The hallmark symptoms of Sjögren syndrome are dry mouth and dry eyes. In addition, Sjogren syndrome may cause skin, nose, and vaginal dryness. It also may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain"
      },
      "child_count": 0,
      "reference_id": "MONDO:0010030"
    },
    {
      "id": 20523,
      "label": "tumor of salivary gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3387,
        7231,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000384",
          "MEDGEN:20641",
          "NCIT:C3361",
          "SCTID:235132004",
          "UMLS:C0036095"
        ],
        "synonyms": [
          "neoplasm of saliva-secreting gland",
          "neoplasm of salivary gland",
          "neoplasm of the salivary gland",
          "saliva-secreting gland neoplasm",
          "saliva-secreting gland neoplasm (disease)",
          "saliva-secreting gland tumor",
          "saliva-secreting gland tumour",
          "salivary gland neoplasm",
          "salivary gland tumor",
          "salivary gland tumour",
          "tumor of saliva-secreting gland",
          "tumor of the salivary gland",
          "tumour of saliva-secreting gland",
          "tumour of the salivary gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the saliva-secreting gland."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021357"
    }
  ],
  "roots": [
    {
      "id": 8301,
      "label": "mouth disorder"
    }
  ]
}