{
  "id": 3410,
  "label": "nephritis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001166",
  "properties": {
    "xrefs": [
      "DOID:10952",
      "EFO:1002050",
      "ICD9:583.7",
      "ICD9:583.89",
      "ICD9:583.9",
      "MEDGEN:14328",
      "MESH:D009393",
      "NCIT:C26833",
      "SCTID:52845002",
      "UMLS:C0027697"
    ],
    "synonyms": [
      "inflammation of kidney",
      "kidney inflammation"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Inflammation of renal tissue."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6948,
      "label": "kidney disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4253
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:557",
          "EFO:0003086",
          "ICD9:583.81",
          "MEDGEN:9635",
          "MESH:D007674",
          "NCIT:C3149",
          "SCTID:90708001",
          "UMLS:C0022658"
        ],
        "synonyms": [
          "disease of kidney",
          "disease or disorder of kidney",
          "disorder of kidney",
          "kidney disease",
          "kidney disease or disorder",
          "kidney disorder",
          "renal disease",
          "renal disorder",
          "nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the kidney."
      },
      "child_count": 57,
      "reference_id": "MONDO:0005240"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 3337,
      "label": "interstitial nephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3410
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1063",
          "ICD10CM:N10-N16",
          "ICD9:583.89",
          "MEDGEN:11952",
          "MESH:D009395",
          "NANDO:2200136",
          "NCIT:C26834",
          "SCTID:28689008",
          "UMLS:C0041349"
        ],
        "synonyms": [
          "Tubulointerstitial nephritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Inflammation of the renal tubules and supporting tissues of the kidney."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001085"
    },
    {
      "id": 4542,
      "label": "glomerulonephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3410,
        19482
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2921",
          "GARD:0006516",
          "HP:0000099",
          "ICD9:583.9",
          "MEDGEN:6616",
          "MESH:D005921",
          "NCIT:C26784",
          "SCTID:36171008",
          "UMLS:C0017658"
        ],
        "synonyms": [
          "glomerular nephritis",
          "glomerulonephritis",
          "glomerulonephritis (disease)",
          "nephritis of renal glomerulus",
          "renal glomerulus nephritis",
          "bright's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A renal disorder characterized by damage in the glomeruli. It may be acute or chronic, focal or diffuse, and it may lead to renal failure. Causes include autoimmune disorders, infections, diabetes, and malignancies."
      },
      "child_count": 40,
      "reference_id": "MONDO:0002462"
    },
    {
      "id": 7021,
      "label": "hereditary nephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3410,
        23932
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:10305",
          "MESH:D009394",
          "SCTID:399340005",
          "UMLS:C0027706"
        ],
        "synonyms": [
          "hereditary nephritis",
          "familial nephritis",
          "nephritis, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A group of inherited conditions characterized initially by hematuria and slowly progressing to renal insufficiency. The most common form is the Alport syndrome (hereditary nephritis with hearing loss) which is caused by mutations in genes for type IV collagen and defective glomerular basement membrane."
      },
      "child_count": 14,
      "reference_id": "MONDO:0005334"
    },
    {
      "id": 8369,
      "label": "pyelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3410
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2744",
          "MEDGEN:48268",
          "MESH:D011702",
          "MedDRA:10037584",
          "NCIT:C34964",
          "SCTID:27174002",
          "UMLS:C0034183"
        ],
        "synonyms": [
          "inflammation of renal pelvis",
          "renal pelvis inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Inflammation of the renal pelvis."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006938"
    }
  ],
  "roots": [
    {
      "id": 6948,
      "label": "kidney disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}