{
  "id": 3436,
  "label": "spotted fever",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001195",
  "properties": {
    "xrefs": [
      "DOID:11104",
      "EFO:1002047",
      "GARD:0019828",
      "ICD10CM:A77",
      "ICD9:082.0",
      "ICD9:083.8",
      "MEDGEN:1826170",
      "Orphanet:102022",
      "SCTID:186771002",
      "UMLS:C5680374",
      "icd11.foundation:9953620"
    ],
    "synonyms": [
      "spotted fever",
      "spotted fever rickettsiae disease",
      "spotted fever rickettsiosis",
      "fever, spotted",
      "fevers, spotted",
      "spotted fever Group Rickettsioses",
      "spotted fever Group rickettsiosis",
      "spotted fevers"
    ],
    "definition": "A type of tick-borne disease which presents on the skin caused by bacteria of the genus Rickettsia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 8360,
      "label": "Rickettsiaceae infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8384,
        20723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001128",
          "GARD:0024503",
          "MESH:D012288"
        ],
        "synonyms": [
          "Rickettsiaceae caused disease or disorder",
          "Rickettsiaceae disease or disorder",
          "Rickettsiaceae infection",
          "infection, Rickettsiaceae",
          "infections, Rickettsiaceae",
          "rickettsialpox"
        ],
        "definition": "Infections with bacteria of the family rickettsiaceae."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006927"
    },
    {
      "id": 23869,
      "label": "vector-borne disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:738484",
          "MESH:D000079426",
          "UMLS:C1640363"
        ],
        "synonyms": [
          "vector-borne infection",
          "vector-borne infectious disease"
        ],
        "definition": "An infectious disease where a pathogen is carried and transmitted by another organism that acts as disease vector."
      },
      "child_count": 49,
      "reference_id": "MONDO:0100120"
    }
  ],
  "children": [
    {
      "id": 2778,
      "label": "African tick-bite fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050035",
          "GARD:0022728",
          "MEDGEN:728968",
          "SCTID:415561000",
          "UMLS:C1320317"
        ],
        "synonyms": [
          "Rickettsia africae spotted fever",
          "South African tick-bite fever"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0000227"
    },
    {
      "id": 2782,
      "label": "Flinders island spotted fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050047",
          "GARD:0022732",
          "MEDGEN:1375989",
          "UMLS:C4505102"
        ],
        "definition": "A spotted fever that has material basis in Rickettsia honei, which is transmitted by cayenne ticks (Amblyomma cajennense). The infection has symptom mild spotted fever, has symptom eschar and has symptom adenopathy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000232"
    },
    {
      "id": 2783,
      "label": "Japanese spotted fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050050",
          "GARD:0022733",
          "MEDGEN:1371298",
          "UMLS:C2108396"
        ],
        "synonyms": [
          "Japanese spotted fever",
          "Japanese spotted fevers",
          "fever, Japanese spotted",
          "fevers, Japanese spotted",
          "oriental spotted fever",
          "spotted fever, Japanese"
        ],
        "definition": "A spotted fever that has material basis in Rickettsia japonica, which is transmitted by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has symptom fever, has symptom eschars, has symptom regional adenopathy, and has symptom rash on extremities."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000233"
    },
    {
      "id": 2784,
      "label": "Rickettsia parkeri spotted fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050051",
          "GARD:0022734"
        ],
        "synonyms": [
          "maculatum infection"
        ],
        "definition": "A spotted fever that has material basis in Rickettsia parkeri, which is transmitted by Gulf Coast tick (Amblyomma maculatum). The infection has symptom fever, has symptom headache, has symptom eschar, and has symptom rash."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000234"
    },
    {
      "id": 2845,
      "label": "Rickettsia helvetica spotted fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436,
        21670
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050484",
          "GARD:0022747"
        ],
        "synonyms": [
          "Rickettsia helvetica aneruptive fever",
          "Rickettsia helvetica caused disease or disorder",
          "Rickettsia helvetica disease or disorder",
          "Rickettsia helvetica infectious disease",
          "aneruptive fever"
        ],
        "definition": "A disease caused by infection with Rickettsia helvetica."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000331"
    },
    {
      "id": 3366,
      "label": "Queensland tick typhus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436,
        21670
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10784",
          "GARD:0022886",
          "ICD10CM:A77.3",
          "ICD9:082.3",
          "MEDGEN:755996",
          "SCTID:68981009",
          "UMLS:C2979888",
          "icd11.foundation:2020851679"
        ],
        "synonyms": [
          "Australian tick typhus"
        ],
        "definition": "A spotted fever that has material basis in Rickettsia australis, which is transmitted by ticks (Ixodes holocyclus). The infection has symptom fever, has symptom headache, has symptom myalgia, has symptom maculopapular rash, and has symptom lymphadenopathy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001118"
    },
    {
      "id": 3398,
      "label": "Siberian tick typhus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10921",
          "GARD:0022894",
          "ICD10CM:A77.2",
          "ICD9:082.2",
          "MEDGEN:639822",
          "SCTID:186781003",
          "UMLS:C0549160",
          "icd11.foundation:490238539"
        ],
        "synonyms": [
          "North Asian tick fever",
          "North Asian tick fever (disorder) [ambiguous]"
        ],
        "definition": "A spotted fever that has material basis in Rickettsia sibirica, which is transmitted by ticks (Dermacentor nuttalli, Dermacentor marginatus and Haemaphysalis concinna). The infection has symptom fever, has symptom eschar, has symptom regional adenopathy, and has symptom maculopapular rash."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001154"
    },
    {
      "id": 7311,
      "label": "Rickettsia conorii infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007179",
          "GARD:0024216"
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0005677"
    },
    {
      "id": 19195,
      "label": "Rocky mountain spotted fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050052",
          "GARD:0007585",
          "ICD10CM:A77.0",
          "MEDGEN:48500",
          "MESH:D012373",
          "MedDRA:10039207",
          "NCIT:C128410",
          "NORD:1674",
          "Orphanet:83311",
          "SCTID:186772009",
          "UMLS:C0035793",
          "icd11.foundation:215936800"
        ],
        "synonyms": [
          "RMSF",
          "Tick typhus"
        ],
        "definition": "Rocky Mountain spotted fever refers to an infection caused by the bacterium Rickettsia rickettsia. This particular bacterium is carried by certain species of ticks and spread to humans through the bites of infected ticks. Signs and symptoms of the condition generally develop approximately 2 to 14 days following the tick bite and may include fever, rash, headache, muscle pain, chills, and/or confusion. Some affected people may also experience diarrhea, nausea, vomiting, light sensitivity, hallucinations, and/or excessive thirst. Most cases occur in the spring and summer and are found in children. Risk factors for developing the conditioninclude recent hiking or exposure to ticks in an area where the disease is known to occur. Rocky Mountain spotted fever is typically treated with antibiotics (such as doxycycline or tetracycline)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019359"
    },
    {
      "id": 19196,
      "label": "rickettsialpox",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11103",
          "GARD:0019030",
          "ICD10CM:A79.1",
          "ICD9:083.2",
          "MEDGEN:19803",
          "MedDRA:10039137",
          "Orphanet:83312",
          "SCTID:75096007",
          "UMLS:C0035597",
          "icd11.foundation:1005140361"
        ],
        "synonyms": [
          "vesicular rickettsiosis"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0019360"
    },
    {
      "id": 19198,
      "label": "pseudotyphus of California",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019034",
          "MEDGEN:1643522",
          "Orphanet:83316",
          "SCTID:764104003",
          "UMLS:C4706680"
        ],
        "definition": "Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a Rickettsia felis infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, occasionally, eschar. lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain. Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019364"
    }
  ],
  "roots": [
    {
      "id": 8360,
      "label": "Rickettsiaceae infectious disease"
    },
    {
      "id": 23869,
      "label": "vector-borne disease"
    }
  ]
}