{
  "id": 3444,
  "label": "esophagus sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001204",
  "properties": {
    "xrefs": [
      "DOID:1114",
      "GARD:0022900",
      "MEDGEN:234233",
      "NCIT:C5341",
      "UMLS:C1333466"
    ],
    "synonyms": [
      "esophageal sarcoma",
      "esophagus sarcoma",
      "sarcoma of esophagus",
      "sarcoma of oesophagus",
      "sarcoma of the esophagus",
      "sarcoma of the oesophagus",
      "sarcoma, esophagus",
      "sarcoma, oesophagus"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A malignant soft tissue neoplasm that arises from the esophagus. Representative examples include Kaposi sarcoma, leiomyosarcoma, rhabdomyosarcoma, and synovial sarcoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 8953,
      "label": "esophageal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        20522
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5041",
          "GARD:0027778",
          "ICD10CM:C15",
          "ICD9:150.3",
          "ICD9:150.4",
          "ICD9:150.5",
          "ICD9:150.8",
          "ICD9:150.9",
          "MEDGEN:107792",
          "NCIT:C7478",
          "OMIM:133239",
          "SCTID:363402007",
          "UMLS:C0546837",
          "icd11.foundation:669033105"
        ],
        "synonyms": [
          "cancer of esophagus",
          "cancer of oesophagus",
          "esophageal cancer",
          "esophageal cancer, somatic",
          "esophageal carcinoma, somatic",
          "esophageal squamous cell carcinoma, somatic",
          "esophagus cancer",
          "malignant esophageal neoplasm",
          "malignant esophageal tumor",
          "malignant esophageal tumour",
          "malignant esophagus neoplasm",
          "malignant esophagus tumor",
          "malignant neoplasm of esophagus",
          "malignant neoplasm of oesophagus",
          "malignant neoplasm of the esophagus",
          "malignant neoplasm of the oesophagus",
          "malignant oesophagus neoplasm",
          "malignant oesophagus tumour",
          "malignant tumor of esophagus",
          "malignant tumor of the esophagus",
          "malignant tumour of oesophagus",
          "malignant tumour of the oesophagus",
          "oesophagus cancer",
          "Ca lower third esophagus",
          "Ca lower third oesophagus",
          "Ca middle third esophagus",
          "Ca middle third oesophagus",
          "malignant neoplasm of distal third of esophagus",
          "malignant neoplasm of distal third of oesophagus",
          "malignant neoplasm of lower third of esophagus",
          "malignant neoplasm of lower third of oesophagus",
          "malignant neoplasm of middle third of esophagus",
          "malignant neoplasm of middle third of oesophagus",
          "malignant neoplasm of proximal third of esophagus",
          "malignant neoplasm of proximal third of oesophagus",
          "malignant neoplasm of upper third esophagus",
          "malignant neoplasm of upper third oesophagus",
          "malignant tumor of abdominal esophagus",
          "malignant tumor of distal third of esophagus",
          "malignant tumor of proximal third of esophagus",
          "malignant tumor of the middle third of the esophagus",
          "malignant tumour of abdominal oesophagus",
          "malignant tumour of distal third of oesophagus",
          "malignant tumour of proximal third of oesophagus",
          "malignant tumour of the middle third of the oesophagus",
          "Aerodigestive tract cancer, susceptibility to",
          "Escc, susceptibility to",
          "esophageal squamous cell carcinoma, susceptibility to",
          "gastric cardia adenocarcinoma, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the esophagus."
      },
      "child_count": 14,
      "reference_id": "MONDO:0007576"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 5300,
      "label": "esophagus leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3444,
        6788
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5276",
          "GARD:0023479",
          "MEDGEN:272589",
          "NCIT:C5334",
          "UMLS:C1333454",
          "icd11.foundation:1419925892"
        ],
        "synonyms": [
          "esophageal leiomyosarcoma",
          "esophagus leiomyosarcoma",
          "leiomyosarcoma of esophagus",
          "leiomyosarcoma of oesophagus",
          "leiomyosarcoma of the esophagus",
          "leiomyosarcoma of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the esophagus. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003365"
    },
    {
      "id": 5481,
      "label": "esophagus liposarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3444,
        6790
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5694",
          "GARD:0023570",
          "MEDGEN:232163",
          "NCIT:C5705",
          "UMLS:C1333456"
        ],
        "synonyms": [
          "esophageal liposarcoma",
          "esophagus liposarcoma",
          "liposarcoma of esophagus",
          "liposarcoma of the esophagus",
          "liposarcoma of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant adipose tissue neoplasm of the esophagus, characterized by multivacuolated lipoblasts with hyperchromatic nuclei, a solid pattern of growth, and a rich vascular network. It arises from the mucosal and submucosal layers of the lower esophagus. Clinical presentation includes progressive dysphagia, nausea, throat discomfort, and foreign body sensation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003586"
    }
  ],
  "roots": [
    {
      "id": 8953,
      "label": "esophageal cancer"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}