{
  "id": 3463,
  "label": "parathyroid gland disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001223",
  "properties": {
    "xrefs": [
      "DOID:11201",
      "EFO:0005754",
      "ICD9:252",
      "ICD9:252.8",
      "ICD9:252.9",
      "MEDGEN:893009",
      "MESH:D010279",
      "NCIT:C26844",
      "SCTID:73132005",
      "UMLS:C4025822",
      "icd11.foundation:962023213"
    ],
    "synonyms": [
      "disease of parathyroid gland",
      "disease or disorder of parathyroid gland",
      "disorder of parathyroid gland",
      "parathyroid disease",
      "parathyroid gland disease",
      "parathyroid gland disease or disorder",
      "parathyroid gland diseases",
      "parathyroid gland disorder",
      "parathyroid gland disorders"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A disease involving the parathyroid gland."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6875,
      "label": "endocrine system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:28",
          "EFO:0001379",
          "ICD9:259.8",
          "ICD9:259.9",
          "MEDGEN:4043",
          "MESH:D004700",
          "NANDO:1100009",
          "NANDO:2100109",
          "NCIT:C3009",
          "SCTID:362969004",
          "UMLS:C0014130"
        ],
        "synonyms": [
          "disease of endocrine system",
          "disease or disorder of endocrine system",
          "disorder of endocrine system",
          "endocrine disease",
          "endocrine disorder",
          "endocrine system disease",
          "endocrine system disease or disorder",
          "endocrine system disorder",
          "endocrinopathy",
          "thyroid or other glandular disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the endocrine system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005151"
    }
  ],
  "children": [
    {
      "id": 3460,
      "label": "hypoparathyroidism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3463
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11199",
          "EFO:0009451",
          "GARD:0006733",
          "ICD10CM:E20",
          "ICD10WHO:E20",
          "ICD9:252.1",
          "MEDGEN:6985",
          "MESH:D007011",
          "NANDO:1200775",
          "NANDO:2100124",
          "NANDO:2200345",
          "NCIT:C78350",
          "SCTID:36976004",
          "UMLS:C0020626",
          "icd11.foundation:1708733050"
        ],
        "synonyms": [
          "hypoparathyroidism, idiopathic (subtype)",
          "parathyroid, underactivity of"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Hypoparathyroidism is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001220"
    },
    {
      "id": 3927,
      "label": "hyperparathyroidism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3463
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13543",
          "EFO:0008506",
          "ICD9:252.0",
          "ICD9:252.00",
          "MEDGEN:6967",
          "MESH:D006961",
          "NANDO:2100123",
          "NANDO:2200343",
          "NCIT:C48259",
          "SCTID:66999008",
          "UMLS:C0020502",
          "icd11.foundation:9633776"
        ],
        "synonyms": [
          "hyperparathyroidism"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It may be primary or secondary; primary hyperparathyroidism is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. Secondary hyperparathyroidism is caused by the chronic stimulation of the parathyroid glands in patients with chronic renal failure, rickets, and malabsorption syndromes."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001741"
    },
    {
      "id": 7880,
      "label": "parathyroid hyperplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3463,
        6775
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000457",
          "HP:0008208",
          "MEDGEN:75767",
          "NCIT:C3989",
          "SCTID:9092004",
          "UMLS:C0271844"
        ],
        "synonyms": [
          "hyperplasia of parathyroid",
          "hyperplasia of the parathyroid",
          "parathyroid gland hyperplasia",
          "parathyroid hyperplasia",
          "parathyroid hyperplasia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A hyperplasia that involves the parathyroid gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006354"
    },
    {
      "id": 20525,
      "label": "tumor of parathyroid gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3463,
        4223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.7",
          "MEDGEN:10586",
          "NCIT:C3313",
          "SCTID:127020005",
          "UMLS:C0030521"
        ],
        "synonyms": [
          "neoplasm of parathyroid",
          "neoplasm of parathyroid gland",
          "neoplasm of the parathyroid",
          "neoplasm of the parathyroid gland",
          "parathyroid gland neoplasm",
          "parathyroid gland neoplasm (disease)",
          "parathyroid gland tumor",
          "parathyroid gland tumour",
          "parathyroid neoplasm",
          "parathyroid tumor",
          "parathyroid tumour",
          "tumor of parathyroid",
          "tumor of parathyroid gland",
          "tumor of the parathyroid",
          "tumor of the parathyroid gland",
          "tumour of parathyroid",
          "tumour of the parathyroid",
          "tumour of the parathyroid gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the parathyroid gland."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021360"
    }
  ],
  "roots": [
    {
      "id": 6875,
      "label": "endocrine system disorder"
    }
  ]
}