{
  "id": 3480,
  "label": "neonatal anemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001240",
  "properties": {
    "xrefs": [
      "DOID:11244",
      "MEDGEN:1530",
      "MESH:D000751",
      "SCTID:234350007",
      "UMLS:C0002891"
    ],
    "synonyms": [
      "anemia neonatal"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4394,
      "label": "anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2355",
          "HP:0001903",
          "ICD9:285.8",
          "ICD9:285.9",
          "MEDGEN:1526",
          "MESH:D000740",
          "NCIT:C2869",
          "SCTID:271737000",
          "UMLS:C0002871"
        ],
        "synonyms": [
          "anaemia (disease)",
          "anemia",
          "anemia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability."
      },
      "child_count": 19,
      "reference_id": "MONDO:0002280"
    }
  ],
  "children": [
    {
      "id": 3479,
      "label": "anemia of prematurity",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3480
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11243",
          "GARD:0022904",
          "ICD10CM:P61.2",
          "ICD9:776.6",
          "MEDGEN:472907",
          "NCIT:C97167",
          "SCTID:47100003",
          "UMLS:C0158996"
        ],
        "synonyms": [
          "AOP"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001239"
    },
    {
      "id": 8048,
      "label": "kernicterus due to isoimmunization",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3480,
        18517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12043",
          "GARD:0024440",
          "ICD10CM:P57.0",
          "ICD9:773.4",
          "MEDGEN:542597",
          "NCIT:C101270",
          "SCTID:359007",
          "UMLS:C0270204",
          "icd11.foundation:1111245443"
        ],
        "synonyms": [
          "kernicterus - due to isoimm.",
          "kernicterus due to isoimmunization of fetus or newborn",
          "kernicterus due to isoimmunization of foetus or newborn",
          "kernicterus related to isoimmunization"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Encephalopathy in infants due to high levels of unconjugated bilirubin that are a result of Rh incompatibility between the mother and the fetus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006567"
    },
    {
      "id": 19546,
      "label": "twin to twin transfusion syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3480,
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13576",
          "EFO:1001221",
          "GARD:0000325",
          "MEDGEN:777055",
          "MESH:D005330",
          "MedDRA:10058328",
          "NCIT:C113824",
          "NORD:2021",
          "Orphanet:95431",
          "SCTID:13404009",
          "UMLS:C2909036",
          "icd11.foundation:850604370"
        ],
        "synonyms": [
          "Feto-fetal transfusion syndrome",
          "Twin Anemia Polycythemia Sequence",
          "Twin-Twin transfusion syndrome",
          "foetal blood loss from foetal haemorrhage into co-twin",
          "foetal haemorrhage into co-twin",
          "placental transfusion syndrome",
          "stuck Twin syndrome",
          "twin-to-twin transfusion syndrome",
          "Fetofetal transfusion syndrome",
          "TTTS",
          "fetal transfusion syndrome",
          "foetal transfusion syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Twin twin transfusion syndrome (TTTS) is a rare condition seen in twin monochorionic pregnancies, typically developing during the 15-26 week gestation period and usually due to unbalanced intertwin placental anastomoses, where an unequal exchange of blood between twins causes oligohydramnios in one sac and polyhydramnios in the other which can lead to a high perinatal mortality rate and a high rate of disability in survivors if left untreated"
      },
      "child_count": 2,
      "reference_id": "MONDO:0019805"
    }
  ],
  "roots": [
    {
      "id": 4394,
      "label": "anemia"
    }
  ]
}