{
  "id": 3486,
  "label": "typhus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001246",
  "properties": {
    "xrefs": [
      "DOID:11256",
      "EFO:0009117",
      "GARD:0019829",
      "ICD10CM:A75",
      "ICD9:080",
      "ICD9:081.0",
      "ICD9:081.9",
      "MEDGEN:11976",
      "Orphanet:102023",
      "SCTID:240613006",
      "UMLS:C0041471",
      "icd11.foundation:292650041"
    ],
    "synonyms": [
      "typhus fever",
      "typhus-group rickettsiae disease",
      "typhus-group rickettsiosis",
      "endemic flea-borne typhus",
      "endemic typhus fever",
      "epidemic louse-borne typhus",
      "exanthematic typhus fever",
      "flea typhus",
      "louse-borne [epidemic] typhus",
      "murine [endemic] typhus",
      "Moscow typhus",
      "classical typhus (fever)",
      "gaol fever"
    ],
    "definition": "A group of infectious diseases that include epidemic typhus, scrub typhus and murine typhus."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 8360,
      "label": "Rickettsiaceae infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8384,
        20723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001128",
          "GARD:0024503",
          "MESH:D012288"
        ],
        "synonyms": [
          "Rickettsiaceae caused disease or disorder",
          "Rickettsiaceae disease or disorder",
          "Rickettsiaceae infection",
          "infection, Rickettsiaceae",
          "infections, Rickettsiaceae",
          "rickettsialpox"
        ],
        "definition": "Infections with bacteria of the family rickettsiaceae."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006927"
    },
    {
      "id": 23869,
      "label": "vector-borne disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:738484",
          "MESH:D000079426",
          "UMLS:C1640363"
        ],
        "synonyms": [
          "vector-borne infection",
          "vector-borne infectious disease"
        ],
        "definition": "An infectious disease where a pathogen is carried and transmitted by another organism that acts as disease vector."
      },
      "child_count": 49,
      "reference_id": "MONDO:0100120"
    }
  ],
  "children": [
    {
      "id": 2844,
      "label": "endemic typhus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3486
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050481",
          "GARD:0019033",
          "MEDGEN:11977",
          "MESH:D014437",
          "MedDRA:10028282",
          "NCIT:C84688",
          "Orphanet:83315",
          "UMLS:C0041472",
          "icd11.foundation:4659958"
        ],
        "synonyms": [
          "endemic flea-borne typhus",
          "endemic typhus fever",
          "murine typhus",
          "urban typhus"
        ],
        "definition": "A bacterial infection caused by Rickettsia typhi."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000330"
    },
    {
      "id": 19197,
      "label": "epidemic louse-borne typhus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3486
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050480",
          "GARD:0019032",
          "MEDGEN:21744",
          "MedDRA:10014979",
          "NCIT:C84689",
          "Orphanet:83314",
          "UMLS:C0041473",
          "icd11.foundation:295798687"
        ],
        "synonyms": [
          "typhus",
          "epidemic louse-borne typhus",
          "epidemic typhus",
          "epidemic typhus fever"
        ],
        "definition": "A gram-negative bacterial infection caused by Rickettsia prowazekii. It is spread by lice infected with the bacteria. Signs and symptoms include sudden headache, generalized muscle pain, malaise, and macular skin lesions. The infection may affect the central nervous system causing encephalitis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019362"
    },
    {
      "id": 19199,
      "label": "scrub typhus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3486,
        24380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13371",
          "EFO:0007480",
          "GARD:0019035",
          "ICD10CM:A75.3",
          "ICD9:081.2",
          "MEDGEN:48591",
          "MESH:D012612",
          "MedDRA:10039766",
          "Orphanet:83317",
          "SCTID:271425001",
          "UMLS:C0036472",
          "icd11.foundation:1695340384"
        ],
        "synonyms": [
          "Japanese river fever",
          "Kedani fever",
          "scrub mite-borne typhus",
          "tsutsugamushi",
          "tsutsugamushi disease",
          "tsutsugamushi fever"
        ],
        "definition": "Scrub typhus is a rare dust mite-borne infectious disease caused by the Orientia tsutsugamushi bacterium and characterized clinically by an eruptive fever which is potentially serious."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019365"
    }
  ],
  "roots": [
    {
      "id": 8360,
      "label": "Rickettsiaceae infectious disease"
    },
    {
      "id": 23869,
      "label": "vector-borne disease"
    }
  ]
}