{
  "id": 3513,
  "label": "intraspinal meningioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001279",
  "properties": {
    "xrefs": [
      "DOID:1140",
      "GARD:0022914",
      "NCIT:C5134"
    ],
    "synonyms": [
      "intraspinal meningioma",
      "meningioma of spinal canal and spinal cord",
      "meningioma of the spinal canal and spinal cord"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A meningioma that arises from the spinal meninges."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 17113,
      "label": "meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3565",
          "GARD:0007015",
          "HP:0002858",
          "ICDO:9530/0",
          "MEDGEN:7532",
          "MESH:D008579",
          "MedDRA:10027191",
          "NANDO:2200094",
          "NCIT:C3230",
          "NORD:1434",
          "ONCOTREE:MNG",
          "Orphanet:2495",
          "SCTID:302820008",
          "UMLS:C0025286",
          "icd11.foundation:672106711"
        ],
        "synonyms": [
          "meningioma",
          "meningioma (disease)",
          "intracranial meningioma",
          "meningeal neoplasm",
          "meningothelial cell tumor",
          "meningothelial cell tumour",
          "primary meningeal tumor",
          "primary meningeal tumour",
          "supratentorial meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)"
      },
      "child_count": 37,
      "reference_id": "MONDO:0016642"
    }
  ],
  "children": [
    {
      "id": 3510,
      "label": "spinal meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513,
        20444
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1138",
          "GARD:0010264",
          "MEDGEN:87576",
          "NCIT:C6935",
          "SCTID:189167009",
          "UMLS:C0347515"
        ],
        "synonyms": [
          "meningioma (disease) of spinal cord",
          "meningioma of spinal cord",
          "meningioma of the spinal cord",
          "spinal cord meningioma",
          "spinal cord meningioma (disease)",
          "meningioma, spine"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Spinal meningioma isa rare type of spinal cord cancer. The spinal cord is part of the central nervous system. This tumor often affects middle-aged women. Tumors of the spinal cord can be either primary or arise from other primary tumors (metastatic), and are typically slow growing. The initial signs and symptoms include headacheand recent onset of seizures. Other features are motor deficits, sensory deficits, pain, and sphincter dysfunction. The thoracic spine (middle back) is the most common site, followed by the cervical spine (neck). These tumors are rarely seen in the lumbar region (lower back). T he only proven risk factor in the development of meningioma is exposure to ionizing radiation. Also, patients with neurofibromatosis type 2 are at increased risk of developing meningioma. Surgery is the treatment of choice and complete tumor removal is reached in the vast majority of patients. The prognosis after surgical resection is excellent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001275"
    },
    {
      "id": 4808,
      "label": "epidural spinal canal meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3809",
          "GARD:0023243",
          "MEDGEN:232462",
          "NCIT:C5310",
          "UMLS:C1333417"
        ],
        "synonyms": [
          "meningioma of epidural spinal canal",
          "meningioma of the epidural spinal canal"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that arises in the epidural spinal canal space."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002778"
    },
    {
      "id": 5650,
      "label": "thoracic spinal canal and spinal cord meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6103",
          "GARD:0023661",
          "MEDGEN:234424",
          "NCIT:C5297",
          "UMLS:C1336738"
        ],
        "synonyms": [
          "meningioma of thoracic spinal canal and spinal cord",
          "thoracic intraspinal meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that arises from the meninges of the thoracic region of the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003770"
    },
    {
      "id": 6076,
      "label": "lumbar spinal canal and spinal cord meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7515",
          "GARD:0023901",
          "MEDGEN:232707",
          "NCIT:C5298",
          "UMLS:C1334436"
        ],
        "synonyms": [
          "lumbar intraspinal meningioma",
          "meningioma of the lumbar spinal canal and spinal cord"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that arises from the meninges of the lumbar region of the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004256"
    },
    {
      "id": 6133,
      "label": "multiple spinal canal and spinal cord meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7646",
          "GARD:0023930",
          "MEDGEN:235341",
          "NCIT:C5275",
          "UMLS:C1334825"
        ],
        "synonyms": [
          "multiple Meningiomas of spinal canal and spinal cord",
          "multiple intraspinal Meningiomas",
          "multiple spinal canal and spinal cord Meningiomas"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Multiple meningiomas that arises from the spinal meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004317"
    },
    {
      "id": 6206,
      "label": "cervical spinal canal and spinal cord meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7915",
          "GARD:0023976",
          "MEDGEN:272451",
          "NCIT:C5296",
          "UMLS:C1332916"
        ],
        "synonyms": [
          "cervical intraspinal meningioma",
          "meningioma of cervical spinal canal and spinal cord"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that arises from the meninges of the cervical region of the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004396"
    },
    {
      "id": 6300,
      "label": "sacral spinal canal and spinal cord meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8203",
          "GARD:0024037",
          "MEDGEN:277626",
          "NCIT:C5299",
          "UMLS:C1335893"
        ],
        "synonyms": [
          "meningioma of sacral spinal canal and spinal cord",
          "sacral intraspinal meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that arises from the meninges of the sacral region of the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004498"
    }
  ],
  "roots": [
    {
      "id": 17113,
      "label": "meningioma"
    }
  ]
}