{
  "id": 3618,
  "label": "mononeuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001397",
  "properties": {
    "xrefs": [
      "DOID:1188",
      "EFO:0009558",
      "MEDGEN:99214",
      "MESH:D020422",
      "SCTID:128189008",
      "UMLS:C0494491",
      "icd11.foundation:1866592137"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 6950,
      "label": "peripheral neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5512,
        18957
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:870",
          "EFO:0003100",
          "MEDGEN:18386",
          "MedDRA:10034606",
          "NCIT:C119734",
          "NCIT:C4731",
          "SCTID:302226006",
          "SCTID:386033004",
          "UMLS:C0031117"
        ],
        "synonyms": [
          "neuropathy",
          "peripheral nerve disorder",
          "peripheral neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005244"
    }
  ],
  "children": [
    {
      "id": 3674,
      "label": "radial neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3618,
        8150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12171",
          "GARD:0022947",
          "MEDGEN:148185",
          "MESH:D020425",
          "SCTID:16644004",
          "UMLS:C0748226"
        ],
        "synonyms": [
          "peripheral neuropathy of radial nerve",
          "radial nerve peripheral neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Disease involving the radial nerve. Clinical features include weakness of elbow extension, elbow flexion, supination of the forearm, wrist and finger extension, and thumb abduction. Sensation may be impaired over regions of the dorsal forearm. Common sites of compression or traumatic injury include the axilla and radial groove of the humerus."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001459"
    },
    {
      "id": 4256,
      "label": "mononeuritis simplex",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3618,
        4257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1802",
          "ICD9:355.9",
          "MEDGEN:65914",
          "SCTID:32595002",
          "UMLS:C0235880"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neuritis of a single nerve."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002121"
    },
    {
      "id": 4917,
      "label": "peroneal neuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3618
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4201",
          "GARD:0023296",
          "MEDGEN:148182",
          "MESH:D020427",
          "NCIT:C27596",
          "UMLS:C0747533"
        ],
        "synonyms": [
          "peroneal neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Disease involving the common peroneal nerve or its branches, the deep and superficial peroneal nerves. Lesions of the deep peroneal nerve are associated with paralysis of dorsiflexion of the ankle and toes and loss of sensation from the web space between the first and second toe. Lesions of the superficial peroneal nerve result in weakness or paralysis of the peroneal muscles (which evert the foot) and loss of sensation over the dorsal and lateral surface of the leg. Traumatic injury to the common peroneal nerve near the head of the fibula is a relatively common cause of this condition. (From Joynt, Clinical Neurology, 1995, Ch51, p31)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0002910"
    },
    {
      "id": 8213,
      "label": "femoral neuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3618,
        21363
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4196",
          "GARD:0024467",
          "ICD9:355.2",
          "MEDGEN:148421",
          "MESH:D020428",
          "NCIT:C27595",
          "SCTID:25690000",
          "UMLS:C0751931"
        ],
        "synonyms": [
          "femoral nerve peripheral nerve lesion",
          "peripheral nerve lesion of femoral nerve"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neuropathy of the femoral nerve."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006759"
    },
    {
      "id": 8386,
      "label": "sciatic neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3618
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11446",
          "EFO:1001166",
          "MEDGEN:57705",
          "MESH:D020426",
          "MedDRA:10048950",
          "SCTID:52585001",
          "UMLS:C0149940"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Disease or damage involving the SCIATIC NERVE, which divides into the PERONEAL NERVE and TIBIAL NERVE (see also PERONEAL NEUROPATHIES and TIBIAL NEUROPATHY). Clinical manifestations may include SCIATICA or pain localized to the hip, PARESIS or PARALYSIS of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. The sciatic nerve may be affected by trauma; ISCHEMIA; COLLAGEN DISEASES; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1363)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0006960"
    },
    {
      "id": 8420,
      "label": "tibial neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3618
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1187",
          "MEDGEN:148422",
          "MESH:D020429",
          "SCTID:399076001",
          "UMLS:C0751932"
        ],
        "synonyms": [
          "tibial neuropathy (disorder) [ambiguous]"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Disease of the tibial nerve (also referred to as the posterior tibial nerve). The most commonly associated condition is the tarsal tunnel syndrome. However, leg injuries; ischemia; and inflammatory conditions (e.g., collagen diseases) may also affect the nerve. Clinical features include paralysis of plantar flexion, ankle inversion and toe flexion as well as loss of sensation over the sole of the foot. (From Joynt, Clinical Neurology, 1995, Ch51, p32)"
      },
      "child_count": 1,
      "reference_id": "MONDO:0006997"
    },
    {
      "id": 8428,
      "label": "ulnar neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3618,
        8150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4613",
          "EFO:1001224",
          "MEDGEN:57596",
          "MESH:D020424",
          "SCTID:359837005",
          "UMLS:C0154743"
        ],
        "synonyms": [
          "mononeuropathy of ulnar nerve",
          "ulnar nerve mononeuropathy",
          "ulnar neuropathy (disorder) [ambiguous]"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Disease involving the ulnar nerve from its origin in the brachial plexus to its termination in the hand. Clinical manifestations may include paresis or paralysis of wrist flexion, finger flexion, thumb adduction, finger abduction, and finger adduction. Sensation over the medial palm, fifth finger, and ulnar aspect of the ring finger may also be impaired. Common sites of injury include the axilla, cubital tunnel at the elbow, and Guyon's canal at the wrist. (From Joynt, Clinical Neurology, 1995, Ch51 pp43-5)"
      },
      "child_count": 4,
      "reference_id": "MONDO:0007006"
    }
  ],
  "roots": [
    {
      "id": 6950,
      "label": "peripheral neuropathy"
    }
  ]
}