{
  "id": 3630,
  "label": "esophagitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001409",
  "properties": {
    "xrefs": [
      "DOID:11963",
      "HP:0100633",
      "ICD10CM:K20",
      "ICD9:530.1",
      "ICD9:530.10",
      "ICD9:530.12",
      "MEDGEN:4549",
      "MESH:D004941",
      "NCIT:C9224",
      "SCTID:16761005",
      "UMLS:C0014868",
      "icd11.foundation:1540965840"
    ],
    "synonyms": [
      "esophagitis",
      "esophagitis (disease)",
      "esophagus inflammation",
      "inflammation of esophagus",
      "inflammation of oesophagus",
      "oesophagus inflammation",
      "acute esophagitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An acute or chronic inflammatory disease affecting the esophageal wall."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 5629,
      "label": "esophageal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6050",
          "EFO:0009544",
          "ICD9:530",
          "ICD9:530.2",
          "ICD9:530.20",
          "ICD9:530.9",
          "MEDGEN:8693",
          "MESH:D004935",
          "NCIT:C3027",
          "SCTID:30811009",
          "SCTID:37657006",
          "UMLS:C0014852",
          "icd11.foundation:1594312948"
        ],
        "synonyms": [
          "disease of esophagus",
          "disease of oesophagus",
          "disease or disorder of esophagus",
          "disease or disorder of oesophagus",
          "disorder of esophagus",
          "disorder of oesophagus",
          "esophageal disorder",
          "esophagus disease",
          "esophagus disease or disorder",
          "oesophagus disease",
          "oesophagus disease or disorder",
          "esophageal ulcer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003749"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 3845,
      "label": "fungal esophagitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3630,
        4188,
        23208,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13147",
          "ICD9:117.9",
          "MEDGEN:90960",
          "NCIT:C27107",
          "SCTID:235602008",
          "UMLS:C0341109"
        ],
        "synonyms": [
          "fungal esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Infection of the esophagus caused by fungi, most often candida albicans and candida tropicalis. It usually affects patients with immunodeficiency disorders or diabetes mellitus. Symptoms include dysphagia and pain on swallowing."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001649"
    },
    {
      "id": 4012,
      "label": "bacterial esophagitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        23208,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13921",
          "MEDGEN:83319",
          "NCIT:C27106",
          "SCTID:235601001",
          "UMLS:C0341108"
        ],
        "synonyms": [
          "bacterial esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An acute bacterial infection that affects the esophagus. Symptoms include severe pain on swallowing and retrosternal pain. Endoscopic examination reveals esophageal mucosal ulcerations and pseudomembranous formations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001832"
    },
    {
      "id": 5713,
      "label": "viral esophagitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        6834,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6297",
          "MEDGEN:87414",
          "NCIT:C27108",
          "SCTID:235603003",
          "UMLS:C0341110"
        ],
        "synonyms": [
          "Viruses caused esophagitis (disease)",
          "Viruses esophagitis (disease)",
          "viral esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Viral infection of the esophagus. It often occurs in immunocompromised patients and it is caused by cytomegalovirus or herpes simplex virus. Symptoms include pain on swallowing, fever, and retrosternal burning."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003846"
    },
    {
      "id": 7044,
      "label": "eosinophilic esophagitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3630,
        18486
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13922",
          "EFO:0004232",
          "GARD:0027720",
          "ICD10CM:K20.0",
          "ICD9:530.13",
          "MEDGEN:83318",
          "MESH:D057765",
          "MedDRA:10064212",
          "NANDO:1200456",
          "NCIT:C27105",
          "Orphanet:73247",
          "SCTID:235599003",
          "UMLS:C0341106"
        ],
        "synonyms": [
          "EoE"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Eosinophilic esophagitis (EoE) is a chronic, allergic disease of the esophagus characterized clinically by symptoms of esophageal dysfunction (including vomiting, dysphagia, feeding disorders, food impaction and abdominal pain) which persist after treatment with proton pump inhibitors (PPIs)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005361"
    },
    {
      "id": 8334,
      "label": "peptic esophagitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        6067,
        23436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13976",
          "EFO:1001095",
          "ICD9:530.11",
          "MEDGEN:5028",
          "MESH:D004942",
          "SCTID:57643001",
          "UMLS:C0014869"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Inflammation of the esophagus that is caused by the reflux of gastric juice with contents of the stomach and duodenum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006896"
    },
    {
      "id": 21051,
      "label": "Crohn disease of the esophagus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        6749
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:574175",
          "UMLS:C0341116"
        ],
        "synonyms": [
          "Crohn's disease of the esophagus",
          "Crohn's disease of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A Crohn disease involving a pathogenic inflammatory response in the esophagus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022901"
    }
  ],
  "roots": [
    {
      "id": 5629,
      "label": "esophageal disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}