{
  "id": 3637,
  "label": "female reproductive organ cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001416",
  "properties": {
    "xrefs": [
      "DOID:120",
      "EFO:1001331",
      "ICD10CM:C51-C58",
      "ICD9:184",
      "MEDGEN:195944",
      "NCIT:C4913",
      "SCTID:126907002",
      "UMLS:C0699889"
    ],
    "synonyms": [
      "cancer of female reproductive organ",
      "female reproductive cancer",
      "female reproductive organ cancer",
      "gynecologic cancer",
      "malignant female reproductive organ neoplasm",
      "malignant female reproductive system neoplasm",
      "malignant female reproductive system tumor",
      "malignant female reproductive system tumour",
      "malignant gynecologic neoplasm",
      "malignant gynecologic tumor",
      "malignant gynecologic tumour",
      "malignant neoplasm of female reproductive organ",
      "malignant neoplasm of female reproductive system",
      "malignant neoplasm of the female reproductive system",
      "malignant tumor of female reproductive system",
      "malignant tumor of the female reproductive system",
      "malignant tumour of female reproductive system",
      "malignant tumour of the female reproductive system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 4279,
      "label": "reproductive system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:193",
          "MEDGEN:233668",
          "NCIT:C36076",
          "UMLS:C1334618"
        ],
        "synonyms": [
          "reproductive tumor",
          "reproductive tumour",
          "cancer of reproductive organ",
          "cancer of reproductive system",
          "malignant neoplasm of reproductive organ",
          "malignant neoplasm of reproductive system",
          "malignant reproductive organ neoplasm",
          "malignant reproductive system neoplasm",
          "reproductive organ cancer",
          "reproductive system cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the reproductive organ"
      },
      "child_count": 16,
      "reference_id": "MONDO:0002149"
    },
    {
      "id": 20384,
      "label": "female reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4379,
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:9004",
          "MESH:D005833",
          "NCIT:C3053",
          "UMLS:C0017416"
        ],
        "synonyms": [
          "female reproductive organ neoplasm (disease)",
          "female reproductive organ tumor",
          "female reproductive organ tumour",
          "female reproductive system neoplasm",
          "female reproductive system neoplasm (disease)",
          "female reproductive system tumor",
          "female reproductive system tumour",
          "gynecologic neoplasm",
          "gynecologic tumor",
          "gynecologic tumour",
          "neoplasm of female reproductive organ",
          "neoplasm of female reproductive system",
          "neoplasm of the female reproductive system",
          "tumor of female reproductive system",
          "tumor of the female reproductive system",
          "tumour of female reproductive system",
          "tumour of the female reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign, precancerous, or malignant neoplasm that affects the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, ovarian carcinoma, cervical carcinoma, and endometrial carcinoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021148"
    }
  ],
  "children": [
    {
      "id": 3623,
      "label": "vaginal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        20294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:119",
          "ICD10CM:C52",
          "ICD9:184.0",
          "MEDGEN:12040",
          "MESH:D014625",
          "NCIT:C7410",
          "SCTID:363445000",
          "UMLS:C0042237",
          "icd11.foundation:798353632"
        ],
        "synonyms": [
          "vagina neoplasm",
          "vaginal tumor",
          "vaginal tumour",
          "cancer of vagina",
          "malignant neoplasm of the vagina",
          "malignant neoplasm of vagina",
          "malignant tumor of the vagina",
          "malignant tumor of vagina",
          "malignant tumour of the vagina",
          "malignant tumour of vagina",
          "malignant vagina neoplasm",
          "malignant vagina tumor",
          "malignant vagina tumour",
          "malignant vaginal neoplasm",
          "malignant vaginal tumor",
          "malignant vaginal tumour",
          "vagina cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the vagina. Representative examples include carcinomas and sarcomas."
      },
      "child_count": 10,
      "reference_id": "MONDO:0001402"
    },
    {
      "id": 3735,
      "label": "vulva cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        20293
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1245",
          "GARD:0027581",
          "ICD10CM:C51",
          "ICD9:184.4",
          "MEDGEN:91196",
          "MESH:D014846",
          "NCIT:C7502",
          "SCTID:363367000",
          "UMLS:C0375071",
          "icd11.foundation:1530443809"
        ],
        "synonyms": [
          "neoplasm of vulva",
          "vulval neoplasm",
          "vulvar tumour",
          "cancer of mammalian vulva",
          "malignant mammalian vulva neoplasm",
          "malignant neoplasm of mammalian vulva",
          "malignant neoplasm of the vulva",
          "malignant neoplasm of vulva",
          "malignant neoplasm of vulva unspecified",
          "malignant neoplasm of vulva, unspecified",
          "malignant tumor of the vulva",
          "malignant tumor of vulva",
          "malignant tumour of the vulva",
          "malignant tumour of vulva",
          "malignant vulva neoplasm",
          "malignant vulva tumor",
          "malignant vulva tumour",
          "malignant vulvar neoplasm",
          "malignant vulvar tumor",
          "malignant vulvar tumour",
          "mammalian vulva cancer",
          "vulval cancer",
          "vulvar cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the vulva."
      },
      "child_count": 16,
      "reference_id": "MONDO:0001528"
    },
    {
      "id": 4286,
      "label": "fallopian tube cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        20332
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1964",
          "GARD:0020204",
          "ICD10CM:C57.0",
          "ICD9:183.2",
          "MEDGEN:102276",
          "MedDRA:10025915",
          "NCIT:C7480",
          "Orphanet:180242",
          "SCTID:363444001",
          "UMLS:C0153579",
          "icd11.foundation:459381514"
        ],
        "synonyms": [
          "tumor of the fallopian tube",
          "tumour of the fallopian tube",
          "cancer of fallopian tube",
          "cancer of fallopian tubes",
          "fallopian tube cancer",
          "fallopian tube malignant neoplasm",
          "fallopian tube malignant tumor",
          "fallopian tube malignant tumour",
          "malignant fallopian tube neoplasm",
          "malignant fallopian tube tumor",
          "malignant fallopian tube tumour",
          "malignant neoplasm of fallopian tube",
          "malignant neoplasm of the fallopian tube",
          "malignant neoplasm of uterine tube",
          "malignant tubal tumor",
          "malignant tubal tumour",
          "malignant tumor of fallopian tube",
          "malignant tumor of fallopian tubes",
          "malignant tumor of the fallopian tube",
          "malignant tumour of fallopian tubes",
          "malignant tumour of the fallopian tube",
          "neoplasm, fallopian tube, malignant",
          "tubal cancer",
          "tumor, fallopian tube, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the fallopian tube. Representative examples include carcinoma, carcinosarcoma, and leiomyosarcoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002158"
    },
    {
      "id": 4754,
      "label": "uterine cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        20520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:363",
          "ICD9:179",
          "MEDGEN:57791",
          "MESH:D014594",
          "NCIT:C3552",
          "SCTID:371973000",
          "UMLS:C0153567",
          "icd11.foundation:1551596364"
        ],
        "synonyms": [
          "neoplasm of uterus",
          "tumor of uterus",
          "tumour of uterus",
          "uterine tumor",
          "uterine tumour",
          "uterus neoplasm",
          "cancer of the uterus",
          "cancer of uterus",
          "malignant neoplasm of the uterus",
          "malignant neoplasm of uterus",
          "malignant tumor of the uterus",
          "malignant tumor of uterus",
          "malignant tumour of the uterus",
          "malignant tumour of uterus",
          "malignant uterine neoplasm",
          "malignant uterine tumor",
          "malignant uterine tumour",
          "malignant uterus neoplasm",
          "uterine cancer",
          "uterus cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Primary or metastatic malignant neoplasm involving the uterine corpus and/or the cervix."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002715"
    },
    {
      "id": 4991,
      "label": "adenocarcinofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4422",
          "MEDGEN:266966",
          "NCIT:C40035",
          "UMLS:C1510778"
        ],
        "synonyms": [
          "adenocarcinofibroma",
          "adenofibroma, malignant",
          "malignant adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma arising from the ovary. It is characterized by the presence of malignant epithelial cells in a fibrotic stroma. Histologic variants include clear cell, serous, mucinous, and endometrioid adenocarcinofibroma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002991"
    },
    {
      "id": 6760,
      "label": "endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000466",
          "ICDO:8380/3",
          "MEDGEN:293976",
          "NCIT:C3769",
          "UMLS:C1569637"
        ],
        "synonyms": [
          "endometrioid adenocarcinoma",
          "endometrioid carcinoma",
          "endometrioid carcinoma of female reproductive system",
          "endometrioid carcinoma of the female reproductive system",
          "female reproductive endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An adenocarcinoma characterized by the presence of malignant glandular epithelial cells resembling endometrial cells. It can arise from the uterine body, ovary, fallopian tube, cervix, vagina, and uterine ligament."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005026"
    },
    {
      "id": 7274,
      "label": "adenosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1974",
          "EFO:0007134",
          "ICDO:8933/3",
          "MEDGEN:126",
          "MESH:D018195",
          "NCIT:C9474",
          "UMLS:C0001442"
        ],
        "synonyms": [
          "Mullerian adenosarcoma",
          "Müllerian adenosarcoma",
          "adenosarcoma",
          "adenosarcoma (morphologic abnormality)",
          "mullerian adenosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A low grade malignant neoplasm characterized by the presence of a benign epithelial component (tubular and cleft-like glands) and a low grade sarcomatous component that contains varying amounts of fibrous and smooth muscle tissues. In a minority of cases, the sarcomatous component contains heterologous elements including striated muscle, cartilage, and fat. It occurs in the uterine corpus, ovary, fallopian tube, cervix, and vagina. It may recur and in a minority of cases may metastasize to distant anatomic sites."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005636"
    },
    {
      "id": 9481,
      "label": "ovarian cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        20309
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2394",
          "ICD10CM:C56",
          "ICD9:183.0",
          "MEDGEN:216027",
          "MESH:D010051",
          "NCIT:C7431",
          "OMIM:167000",
          "Orphanet:213500",
          "SCTID:363443007",
          "UMLS:C1140680",
          "icd11.foundation:685124533"
        ],
        "synonyms": [
          "ovarian neoplasm",
          "ovary neoplasm",
          "tumor of the ovary",
          "tumour of the ovary",
          "cancer of ovary",
          "cancer of the ovary",
          "malignant neoplasm of ovary",
          "malignant neoplasm of the ovary",
          "malignant ovarian neoplasm",
          "malignant ovarian tumor",
          "malignant ovarian tumour",
          "malignant ovary neoplasm",
          "malignant tumor of ovary",
          "malignant tumor of the ovary",
          "malignant tumour of ovary",
          "malignant tumour of the ovary",
          "ovarian cancer",
          "ovarian cancer, somatic",
          "ovarian malignant tumor",
          "ovarian malignant tumour",
          "ovary cancer",
          "ovarian cancer, epithelial",
          "primary ovarian cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas."
      },
      "child_count": 22,
      "reference_id": "MONDO:0008170"
    },
    {
      "id": 19993,
      "label": "gestational choriocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        5475,
        6924,
        18866
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2025",
          "GARD:0019712",
          "ICD9:181",
          "MEDGEN:138102",
          "NCIT:C4646",
          "Orphanet:99926",
          "SCTID:417570003",
          "UMLS:C0349557",
          "icd11.foundation:2136066651"
        ],
        "synonyms": [
          "gestational choriocarcinoma",
          "gestational choriocarcinoma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Gestational choriocarcinoma is a gestational trophoblastic tumor (GTT) occurring secondary to pregnancy (ectopic or normal), miscarriage, voluntary termination of pregnancy (VTP) or a hydatidiform mole."
      },
      "child_count": 16,
      "reference_id": "MONDO:0020550"
    }
  ],
  "roots": [
    {
      "id": 4279,
      "label": "reproductive system cancer"
    },
    {
      "id": 20384,
      "label": "female reproductive system neoplasm"
    }
  ]
}