{
  "id": 3695,
  "label": "testicular leukemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001482",
  "properties": {
    "xrefs": [
      "DOID:12286",
      "GARD:0022954",
      "MEDGEN:234941",
      "NCIT:C9277",
      "UMLS:C1336711"
    ],
    "synonyms": [
      "testicular leukemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A myeloid or more commonly lymphoid leukemia (acute or chronic) affecting the testis. Microscopically, there is interstitial infiltration of the testis by leukemic cells. Acute lymphoblastic leukemia with testicular involvement is not uncommon in boys. Sometimes (up to 10% of the cases), testicular involvement may be the initial manifestation of relapsed acute lymphoblastic leukemia. --03"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6789,
      "label": "leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1240",
          "EFO:0000565",
          "HP:0001909",
          "ICD9:207",
          "ICD9:207.8",
          "ICD9:207.80",
          "ICD9:208",
          "ICD9:208.8",
          "ICD9:208.80",
          "ICD9:208.9",
          "ICD9:208.90",
          "ICDO:9800/3",
          "MEDGEN:9725",
          "MESH:D007938",
          "NANDO:2100002",
          "NCIT:C3161",
          "SCTID:93143009",
          "UMLS:C0023418"
        ],
        "synonyms": [
          "blood (leukemia)",
          "leukaemia (disease)",
          "leukemia",
          "leukemia (disease)",
          "leukemia, disease",
          "leukemia, malignant",
          "leukemias",
          "leukemias, general",
          "leukaemia NOS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005059"
    },
    {
      "id": 7111,
      "label": "testicular cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7450,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2998",
          "EFO:0005088",
          "ICD10CM:C62",
          "ICD9:186",
          "ICD9:186.9",
          "MEDGEN:56313",
          "MESH:D013736",
          "NCIT:C7251",
          "SCTID:363449006",
          "UMLS:C0153594"
        ],
        "synonyms": [
          "testicular tumor",
          "testicular tumour",
          "testis neoplasm",
          "cancer of testis",
          "malignant neoplasm of testis",
          "malignant neoplasm of the testis",
          "malignant testicular neoplasm",
          "malignant testicular tumor",
          "malignant testicular tumour",
          "malignant testis neoplasm",
          "malignant tumor of testis",
          "malignant tumor of the testis",
          "malignant tumour of testis",
          "malignant tumour of the testis",
          "testis cancer",
          "paediatric testicular neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005447"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6789,
      "label": "leukemia"
    },
    {
      "id": 7111,
      "label": "testicular cancer"
    }
  ]
}