{
  "id": 3738,
  "label": "blood coagulation disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001531",
  "properties": {
    "xrefs": [
      "DOID:1247",
      "EFO:0009314",
      "ICD9:286",
      "ICD9:286.9",
      "ICD9:287.8",
      "MEDGEN:604",
      "MESH:D001778",
      "NCIT:C2902",
      "SCTID:64779008",
      "UMLS:C0005779"
    ],
    "synonyms": [
      "blood coagulation disorder",
      "coagulation defect",
      "coagulation disorder",
      "coagulation disorder, blood",
      "coagulation disorders, blood",
      "coagulopathy",
      "disorder, blood coagulation",
      "disorders, blood coagulation"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 7217,
      "label": "hematologic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:74",
          "EFO:0005803",
          "GTR:AN1320635",
          "ICD10CM:D50-D89",
          "ICD9:280-289",
          "ICD9:289.8",
          "ICD9:289.9",
          "MEDGEN:5483",
          "MESH:D006402",
          "NANDO:1100006",
          "NANDO:2100175",
          "NCIT:C26323",
          "Orphanet:97992",
          "SCTID:414022008",
          "UMLS:C0018939"
        ],
        "synonyms": [
          "blood disease",
          "blood disorder",
          "disease of hematopoietic system",
          "disease of the blood and blood-forming organs",
          "disease or disorder of haematopoietic system",
          "disease or disorder of hematopoietic system",
          "disorder of haematopoietic system",
          "disorder of hematopoietic system",
          "haematological disease",
          "haematological disorder",
          "haematological system disease",
          "haematopoietic disease",
          "haematopoietic system disease or disorder",
          "hematologic and lymphocytic disorder",
          "hematologic disorder",
          "hematological disease",
          "hematological disorder",
          "hematological system disease",
          "hematopoietic disease",
          "hematopoietic system disease",
          "hematopoietic system disease or disorder",
          "rare hematologic disease",
          "haematological disorders and malignancies",
          "hematological disorders and malignancies"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disease involving the hematopoietic system."
      },
      "child_count": 27,
      "reference_id": "MONDO:0005570"
    }
  ],
  "children": [
    {
      "id": 3021,
      "label": "marantic endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        3738,
        6759
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060068",
          "GARD:0022812",
          "MEDGEN:452215",
          "MESH:D059905",
          "SCTID:57181007",
          "UMLS:C0221390"
        ],
        "synonyms": [
          "nonbacterial thrombotic endocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Formation of a non-infectious thrombus, referred to as vegetation, on previously undamaged endocardium. It usually occurs as a complication of connective-tissue diseases and cancers because of the associated hypercoagulable state (see thrombophilia)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000610"
    },
    {
      "id": 3755,
      "label": "hemolytic-uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12554",
          "GARD:0022233",
          "ICD10CM:D59.3",
          "ICD9:283.11",
          "MEDGEN:42403",
          "MESH:D006463",
          "NCIT:C75545",
          "Orphanet:544458",
          "SCTID:111407006",
          "UMLS:C0019061"
        ],
        "synonyms": [
          "HUS",
          "hemolytic uremic syndrome",
          "acute renal failure, thrombocytopenia, and microangiopathic hemolytic anaemia associated with distorted erythrocytes ('burr cells')",
          "acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells')"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Acute kidney injury associated with microangiopathic hemolytic anemia and thrombocytopenia."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001549"
    },
    {
      "id": 4359,
      "label": "coagulation protein disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2212",
          "GARD:0023096",
          "MEDGEN:108723",
          "MESH:D020147",
          "NCIT:C27215",
          "SCTID:86075001",
          "UMLS:C0600503"
        ],
        "synonyms": [
          "coagulation factor deficiency",
          "coagulation factor deficiency syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital or acquired deficiency of one of the coagulation factors. It results in bleeding."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002242"
    },
    {
      "id": 4413,
      "label": "thrombophilia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2452",
          "EFO:0009315",
          "GARD:0023114",
          "ICD9:286.9",
          "MEDGEN:98306",
          "MESH:D019851",
          "NCIT:C84479",
          "Orphanet:64738",
          "SCTID:234467004",
          "UMLS:C0398623",
          "icd11.foundation:1733531851"
        ],
        "synonyms": [
          "excessive blood clotting",
          "hypercoagulability",
          "hypercoagulability state",
          "hypercoagulable"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002305"
    },
    {
      "id": 8234,
      "label": "hemorrhagic disease of newborn",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3738,
        6861
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000964",
          "GARD:0024471",
          "ICD10CM:P53",
          "ICD9:776.0",
          "MEDGEN:42406",
          "MESH:D006475",
          "MedDRA:10019601",
          "NCIT:C111857",
          "SCTID:12546009",
          "UMLS:C0019088"
        ],
        "synonyms": [
          "hemorrhagic disease of newborn",
          "vitamin K deficiency bleeding in newborn"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A condition characterized as a coagulation disturbance in newborns due to vitamin K deficiency resulting in impaired production of coagulation factors II, VII, IX, and X, and proteins C and S by the liver."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006784"
    },
    {
      "id": 19495,
      "label": "thrombotic microangiopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019227",
          "ICD10CM:M31.1",
          "ICD9:446.6",
          "MEDGEN:403479",
          "MESH:D057049",
          "MedDRA:10043645",
          "NCIT:C62605",
          "Orphanet:93573",
          "SCTID:126729006",
          "UMLS:C2717961"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019737"
    },
    {
      "id": 20411,
      "label": "inherited blood coagulation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2214",
          "GARD:0020319",
          "MEDGEN:163105",
          "MESH:D025861",
          "Orphanet:183654",
          "UMLS:C0852077"
        ],
        "synonyms": [
          "coagulation disorder, hereditary",
          "coagulation disorder, inherited",
          "coagulation disorders, hereditary",
          "coagulation disorders, inherited",
          "hereditary blood coagulation disease",
          "hereditary blood coagulation disorders",
          "hereditary coagulation disorder",
          "hereditary coagulation disorders",
          "inherited blood coagulation disorders",
          "inherited coagulation disorder",
          "inherited coagulation disorders",
          "rare genetic coagulation disorder",
          "inherited blood coagulation disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation."
      },
      "child_count": 78,
      "reference_id": "MONDO:0021181"
    },
    {
      "id": 23419,
      "label": "prekallikrein deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025905",
          "MEDGEN:75779",
          "NANDO:2200684",
          "NCIT:C99022",
          "SCTID:48976006",
          "UMLS:C0272339"
        ],
        "synonyms": [
          "prekallikrein deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A condition characterized by the congenital or acquired deficiency of prekallikrein. This deficiency is usually not associated with bleeding. The congenital deficiency is very rare. Acquired deficiency may occur in diffuse intravascular coagulation, infections, and sickle cell disease."
      },
      "child_count": 1,
      "reference_id": "MONDO:0044744"
    }
  ],
  "roots": [
    {
      "id": 7217,
      "label": "hematologic disorder"
    }
  ]
}