{
  "id": 3803,
  "label": "central nervous system leukemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001606",
  "properties": {
    "xrefs": [
      "DOID:12969",
      "GARD:0022972",
      "MEDGEN:234102",
      "NCIT:C5440",
      "UMLS:C1332884"
    ],
    "synonyms": [
      "CNS leukaemia",
      "CNS leukemia",
      "central nervous system leukaemia (disease)",
      "central nervous system leukemia",
      "central nervous system leukemia (disease)",
      "leukaemia (disease) of central nervous system",
      "leukaemia of CNS",
      "leukaemia of central nervous system",
      "leukaemia of the CNS",
      "leukaemia of the central nervous system",
      "leukemia (disease) of central nervous system",
      "leukemia of CNS",
      "leukemia of central nervous system",
      "leukemia of the CNS",
      "leukemia of the central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Leukemia infiltrating the central nervous system structures."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5530,
      "label": "central nervous system hematopoietic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7694,
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5772",
          "GARD:0023597",
          "MEDGEN:234101",
          "NCIT:C5503",
          "UMLS:C1332882"
        ],
        "synonyms": [
          "CNS haematopoietic neoplasm",
          "CNS haematopoietic tumour",
          "CNS hematopoietic neoplasm",
          "CNS hematopoietic tumor",
          "central nervous system haematopoietic and lymphoid system neoplasm",
          "central nervous system haematopoietic neoplasms",
          "central nervous system haematopoietic tumour",
          "central nervous system hematopoietic and lymphoid system neoplasm",
          "central nervous system hematopoietic neoplasm",
          "central nervous system hematopoietic neoplasms",
          "central nervous system hematopoietic tumor",
          "haematopoietic and lymphoid system neoplasm of central nervous system",
          "haematopoietic neoplasm of CNS",
          "haematopoietic neoplasm of central nervous system",
          "haematopoietic neoplasm of the CNS",
          "haematopoietic neoplasm of the central nervous system",
          "haematopoietic tumour of central nervous system",
          "haematopoietic tumour of the central nervous system",
          "hematopoietic and lymphoid system neoplasm of central nervous system",
          "hematopoietic neoplasm of CNS",
          "hematopoietic neoplasm of central nervous system",
          "hematopoietic neoplasm of the CNS",
          "hematopoietic neoplasm of the central nervous system",
          "hematopoietic tumor of central nervous system",
          "hematopoietic tumor of the central nervous system",
          "lymphomas and hemopoietic neoplasms of CNS",
          "lymphomas and hemopoietic neoplasms of the CNS",
          "central nervous system hematologic cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A primary or metastatic neoplasm of hematopoietic origin that affects the brain, meninges, or spinal cord. Representative examples include Hodgkin and non-Hodgkin lymphomas, histiocytic tumors, and leukemias."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003641"
    },
    {
      "id": 6789,
      "label": "leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1240",
          "EFO:0000565",
          "HP:0001909",
          "ICD9:207",
          "ICD9:207.8",
          "ICD9:207.80",
          "ICD9:208",
          "ICD9:208.8",
          "ICD9:208.80",
          "ICD9:208.9",
          "ICD9:208.90",
          "ICDO:9800/3",
          "MEDGEN:9725",
          "MESH:D007938",
          "NANDO:2100002",
          "NCIT:C3161",
          "SCTID:93143009",
          "UMLS:C0023418"
        ],
        "synonyms": [
          "blood (leukemia)",
          "leukaemia (disease)",
          "leukemia",
          "leukemia (disease)",
          "leukemia, disease",
          "leukemia, malignant",
          "leukemias",
          "leukemias, general",
          "leukaemia NOS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005059"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5530,
      "label": "central nervous system hematopoietic neoplasm"
    },
    {
      "id": 6789,
      "label": "leukemia"
    }
  ]
}