{
  "id": 4004,
  "label": "sick sinus syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001823",
  "properties": {
    "xrefs": [
      "DOID:13884",
      "ICD10CM:I49.5",
      "MEDGEN:20749",
      "MESH:D012804",
      "NANDO:2100043",
      "NANDO:2200212",
      "NCIT:C62244",
      "SCTID:36083008",
      "UMLS:C0037052",
      "icd11.foundation:1682594333"
    ],
    "synonyms": [
      "SSS"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A constellation of signs and symptoms which may include syncope, fatigue, dizziness, and alternating periods of bradycardia and atrial tachycardia, which is caused by sinoatrial node dysfunction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 2930,
      "label": "sinoatrial node disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3258,
        7113
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050824",
          "MEDGEN:98448",
          "UMLS:C0428908"
        ],
        "synonyms": [
          "disease of sinoatrial node",
          "disease or disorder of sinoatrial node",
          "disorder of sinoatrial node",
          "sinoatrial node disease",
          "sinoatrial node disease or disorder",
          "SA node",
          "sinuatrial node"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the sinoatrial node."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000469"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    }
  ],
  "children": [
    {
      "id": 13129,
      "label": "familial sick sinus syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4004,
        26601
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0013663",
          "MEDGEN:573766",
          "MESH:C563907",
          "MedDRA:10040639",
          "OMIMPS:608567",
          "Orphanet:166282",
          "SCTID:233913007",
          "UMLS:C0340491",
          "icd11.foundation:1495462959"
        ],
        "synonyms": [
          "familial sinus node dysfunction",
          "hereditary sick sinus syndrome",
          "SSS1",
          "sick sinus syndrome 1, autosomal recessive"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Sick sinus syndrome is a rare cardiac rhythm disease, usually of the elderly, characterized by electrocardiographic findings of sinus bradycardia, atrial fibrillation, atrial tachycardia sinus arrest, or sino-atrial block, and that manifest with symptoms like syncope, dizziness, palpitations, fatigue, or even heart failure. It results from malfunction of the cardiac conduction system, probably secondary to degenerative fibrosis of nodal tissue in the elderly or secondary to cardiac disorders in younger patients."
      },
      "child_count": 8,
      "reference_id": "MONDO:0012061"
    }
  ],
  "roots": [
    {
      "id": 2930,
      "label": "sinoatrial node disorder"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    }
  ]
}