{
  "id": 4005,
  "label": "polyneuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001824",
  "properties": {
    "xrefs": [
      "DOID:1389",
      "EFO:0009562",
      "ICD9:356.9",
      "ICD9:357.4",
      "MEDGEN:57502",
      "MESH:D011115",
      "NCIT:C26951",
      "SCTID:42345000",
      "UMLS:C0152025",
      "icd11.foundation:58868923"
    ],
    "synonyms": [
      "polyneuropathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A disease or disorder affecting more than one nerve."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6950,
      "label": "peripheral neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5512,
        18957
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:870",
          "EFO:0003100",
          "MEDGEN:18386",
          "MedDRA:10034606",
          "NCIT:C119734",
          "NCIT:C4731",
          "SCTID:302226006",
          "SCTID:386033004",
          "UMLS:C0031117"
        ],
        "synonyms": [
          "neuropathy",
          "peripheral nerve disorder",
          "peripheral neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005244"
    }
  ],
  "children": [
    {
      "id": 3326,
      "label": "idiopathic progressive polyneuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10593",
          "GARD:0022875",
          "ICD9:356.4",
          "MEDGEN:509646",
          "SCTID:33209009",
          "UMLS:C0154756"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001073"
    },
    {
      "id": 3949,
      "label": "polyneuropathy in collagen vascular disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13649",
          "GARD:0023009",
          "ICD9:357.1",
          "ICD9:357.4",
          "MEDGEN:509648",
          "SCTID:193177003",
          "UMLS:C0154759"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001765"
    },
    {
      "id": 4124,
      "label": "critical illness polyneuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14402",
          "GARD:0023046",
          "ICD10CM:G62.81",
          "ICD9:357.82",
          "MEDGEN:140748",
          "SCTID:230594005",
          "UMLS:C0393851"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001957"
    },
    {
      "id": 5272,
      "label": "demyelinating polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005,
        4626
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5214",
          "GARD:0023456",
          "ICD9:356.9",
          "MEDGEN:82859",
          "NCIT:C27062",
          "SCTID:23414001",
          "UMLS:C0270922"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Polyneuropathy that is characterized by demyelination of axons."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003334"
    },
    {
      "id": 5273,
      "label": "chronic polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5221",
          "MEDGEN:223911",
          "NCIT:C36071",
          "UMLS:C1167650"
        ],
        "synonyms": [
          "polyneuropathy, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Polyneuropathy that is persistent or long-standing in nature."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003335"
    },
    {
      "id": 8326,
      "label": "paraneoplastic polyneuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005,
        18348
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8681",
          "GARD:0024499",
          "ICD9:357.3",
          "MEDGEN:124380",
          "MESH:D020364",
          "MedDRA:10062289",
          "NCIT:C3981",
          "SCTID:77659000",
          "UMLS:C0270932"
        ],
        "synonyms": [
          "paraneoplastic polyneuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A diffuse or multifocal peripheral neuropathy caused by the effects of a distant neoplasm. It may be attributed, in part, to the immune response to neoplasm-elaborated proteins. The neuropathy may be sensory, motor, mixed or autonomic. It may be the initial presentation of an occult neoplasm. Detection and resection of the neoplasm may result in cure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006888"
    },
    {
      "id": 8348,
      "label": "polyradiculoneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005,
        4626
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4308",
          "EFO:1001116",
          "GARD:0024500",
          "MEDGEN:46012",
          "MESH:D011129",
          "SCTID:128078004",
          "UMLS:C0032587"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (guillain-barre syndrome) and polyradiculoneuropathy, chronic inflammatory demyelinating. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006915"
    },
    {
      "id": 20732,
      "label": "polyneuritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005,
        4257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GTR:AN1353837",
          "GTR:AN1355640",
          "HP:0031003",
          "MEDGEN:46005",
          "NCIT:C26864",
          "SCTID:76886005",
          "UMLS:C0032541"
        ],
        "synonyms": [
          "polyneuritis",
          "Inflammatory polyneuropathy",
          "Multiple neuritis",
          "Polyneuritides",
          "Polyneuritis",
          "inflammatory polyneuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Inflammation of several peripheral nerves."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021718"
    },
    {
      "id": 24352,
      "label": "toxic polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:G62.2",
          "NCIT:C27063",
          "SCTID:45600000"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Polyneuropathy that is caused by exposure to toxins."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100633"
    },
    {
      "id": 25768,
      "label": "organophosphate-induced delayed polyneuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081393",
          "GARD:0026891"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An inflammatory and toxic neuropathy that is characaterized by a collection of neuropsychological symptoms associated with repeated organophosphate pesticide exposure as well as nerve agent exposure. Symptoms can appear weeks after exposure and include muscle weakness, anxiety, depression, psychosis as well as cognitive and memory deficits."
      },
      "child_count": 0,
      "reference_id": "MONDO:0957912"
    }
  ],
  "roots": [
    {
      "id": 6950,
      "label": "peripheral neuropathy"
    }
  ]
}