{
  "id": 4044,
  "label": "primary angle-closure glaucoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001868",
  "properties": {
    "xrefs": [
      "DOID:1405",
      "EFO:1001506",
      "ICD10CM:H40.2",
      "ICD9:365.2",
      "ICD9:365.20",
      "MEDGEN:42225",
      "NCIT:C34640",
      "SCTID:392288006",
      "UMLS:C0017606"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 3930,
      "label": "angle-closure glaucoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6774
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13550",
          "MEDGEN:6610",
          "MESH:D015812",
          "SCTID:392291006",
          "UMLS:C0017605"
        ],
        "synonyms": [
          "angle closure glaucoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001744"
    }
  ],
  "children": [
    {
      "id": 3928,
      "label": "interval angle-closure glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4044
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13549",
          "ICD10CM:H40.23",
          "ICD9:365.21",
          "MEDGEN:509734",
          "SCTID:65460003",
          "UMLS:C0154945"
        ],
        "synonyms": [
          "intermittent angle-closure glaucoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001742"
    },
    {
      "id": 3998,
      "label": "acute closed-angle glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4044,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13862",
          "ICD10CM:H40.21",
          "ICD9:365.22",
          "MEDGEN:509735",
          "SCTID:30041005",
          "UMLS:C0154946"
        ],
        "synonyms": [
          "acute angle-closure glaucoma",
          "angle-closure glaucoma, acute"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Acute form of angle-closure glaucoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001817"
    },
    {
      "id": 4041,
      "label": "residual stage angle-closure glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4044
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1404",
          "ICD10CM:H40.24",
          "ICD9:365.24",
          "MEDGEN:509737",
          "SCTID:55129006",
          "UMLS:C0154948"
        ],
        "synonyms": [
          "residual stage of angle-closure glaucoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001864"
    },
    {
      "id": 4129,
      "label": "chronic closed-angle glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4044
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14445",
          "ICD10CM:H40.22",
          "ICD9:365.23",
          "MEDGEN:509736",
          "SCTID:33647009",
          "UMLS:C0154947"
        ],
        "synonyms": [
          "anatomical narrow angle glaucoma",
          "angle-closure glaucoma, chronic",
          "chronic angle-closure glaucoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Chronic form of angle-closure glaucoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001966"
    },
    {
      "id": 21820,
      "label": "hereditary glaucoma, primary closed-angle",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4044,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027267",
          "MEDGEN:1712967",
          "OMIM:618880",
          "UMLS:C5394374"
        ],
        "synonyms": [
          "GLCC",
          "glaucoma, primary closed-angle",
          "hereditary primary angle-closure glaucoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0030038"
    }
  ],
  "roots": [
    {
      "id": 3930,
      "label": "angle-closure glaucoma"
    }
  ]
}