{
  "id": 4054,
  "label": "anus cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001879",
  "properties": {
    "xrefs": [
      "DOID:14110",
      "GARD:0009300",
      "ICD9:154.3",
      "MEDGEN:56303",
      "NCIT:C7379",
      "UMLS:C0153446"
    ],
    "synonyms": [
      "anus cancer",
      "cancer of anus",
      "malignant anal neoplasm",
      "malignant anal tumor",
      "malignant anal tumour",
      "malignant anus neoplasm",
      "malignant neoplasm of anus",
      "malignant neoplasm of the anus",
      "malignant tumor of anus",
      "malignant tumor of the anus",
      "malignant tumour of anus",
      "malignant tumour of the anus"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the anus"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 5037,
      "label": "anus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4291,
        4590
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4551",
          "EFO:0003835",
          "MEDGEN:360",
          "MESH:D001005",
          "NCIT:C2877",
          "SCTID:126849006",
          "UMLS:C0003463"
        ],
        "synonyms": [
          "anal neoplasm",
          "anal neoplasms, benign and malignant",
          "anal tumor",
          "anal tumors",
          "anal tumour",
          "anal tumours",
          "anus neoplasm",
          "anus neoplasm (disease)",
          "anus tumor",
          "anus tumour",
          "neoplasm of anus",
          "neoplasm of the anus",
          "tumor of anus",
          "tumor of the anus",
          "tumour of anus",
          "tumour of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003046"
    },
    {
      "id": 8006,
      "label": "rectal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4291,
        7221
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1993",
          "EFO:1000657",
          "ICD10CM:C20",
          "ICD9:154.1",
          "MEDGEN:181763",
          "NCIT:C7418",
          "SCTID:363351006",
          "UMLS:C0949022",
          "icd11.foundation:1113099195"
        ],
        "synonyms": [
          "carcinoma of rectum",
          "carcinoma of the rectum",
          "cancer of rectum",
          "malignant neoplasm of rectum",
          "malignant neoplasm of the rectum",
          "malignant rectal neoplasm",
          "malignant rectal tumor",
          "malignant rectal tumour",
          "malignant rectum neoplasm",
          "malignant rectum tumour",
          "malignant tumor of rectum",
          "malignant tumor of the rectum",
          "malignant tumour of rectum",
          "malignant tumour of the rectum",
          "rectal cancer",
          "rectum cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006519"
    }
  ],
  "children": [
    {
      "id": 4063,
      "label": "anus lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4054,
        4292
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14139",
          "GARD:0023029",
          "MEDGEN:272308",
          "NCIT:C5601",
          "UMLS:C1332268"
        ],
        "synonyms": [
          "anal lymphoma",
          "anus lymphoma",
          "lymphoma of anus",
          "lymphoma of the anus",
          "primary anal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A usually large cell non-Hodgkin lymphoma of B-cell phenotype, arising from the anus. Lymphomas originating from the anal region are rare in the general population, but they are seen with a higher frequency in HIV-positive patients, particularly homosexual men."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001888"
    },
    {
      "id": 4879,
      "label": "anus sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4054,
        4294,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4067",
          "GARD:0023282",
          "MEDGEN:233982",
          "NCIT:C5611",
          "UMLS:C1332277"
        ],
        "synonyms": [
          "anal sarcoma",
          "anus sarcoma",
          "sarcoma of anus",
          "sarcoma of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant soft tissue neoplasm arising from the anus. Representative examples include leiomyosarcoma, rhabdomyosarcoma, and Kaposi sarcoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002865"
    },
    {
      "id": 5158,
      "label": "anal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4054,
        23485
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4908",
          "GARD:0027634",
          "MEDGEN:76006",
          "NCIT:C9291",
          "SCTID:448315008",
          "UMLS:C0279637"
        ],
        "synonyms": [
          "Ca anus",
          "anal cancer",
          "cancer of anus",
          "cancer of the anus",
          "anal carcinoma",
          "anus carcinoma",
          "carcinoma of anus",
          "carcinoma of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the anus"
      },
      "child_count": 8,
      "reference_id": "MONDO:0003199"
    },
    {
      "id": 7658,
      "label": "anal melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4054,
        4293
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14145",
          "EFO:1000080",
          "GARD:0024285",
          "MEDGEN:91151",
          "NCIT:C4639",
          "ONCOTREE:ARMM",
          "SCTID:276821000",
          "UMLS:C0349538"
        ],
        "synonyms": [
          "anal malignant melanoma",
          "anal melanoma",
          "anus melanoma",
          "anus melanoma (disease)",
          "malignant anus melanoma",
          "malignant melanoma of anus",
          "malignant melanoma of the anus",
          "melanoma (disease) of anus",
          "melanoma of anus",
          "melanoma of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A melanoma arising from the anus. Clinical presentation includes rectal bleeding, tenesmus, pain, and change in bowel habit. The prognosis is usually poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006081"
    }
  ],
  "roots": [
    {
      "id": 5037,
      "label": "anus neoplasm"
    },
    {
      "id": 8006,
      "label": "rectal cancer"
    }
  ]
}