{
  "id": 4179,
  "label": "colon carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002032",
  "properties": {
    "xrefs": [
      "DOID:1520",
      "EFO:1001950",
      "MEDGEN:147065",
      "NCIT:C4910",
      "SCTID:269533000",
      "UMLS:C0699790",
      "icd11.foundation:865099988"
    ],
    "synonyms": [
      "colon cancer",
      "carcinoma of colon",
      "carcinoma of the colon",
      "colon carcinoma",
      "colonic carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A carcinoma that arises from epithelial cells of the colon"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 20304,
      "label": "malignant colon neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7078,
        7221
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:219",
          "ICD10CM:C18",
          "ICD9:153",
          "ICD9:153.8",
          "ICD9:153.9",
          "MEDGEN:2839",
          "NCIT:C9242",
          "SCTID:363406005",
          "UMLS:C0007102",
          "icd11.foundation:1265576634"
        ],
        "synonyms": [
          "cancer of colon",
          "colon cancer",
          "colon neoplasm, malignant",
          "colon tumor, malignant",
          "malignant colon neoplasm",
          "malignant colon tumor",
          "malignant colon tumour",
          "malignant colonic neoplasm",
          "malignant colonic tumor",
          "malignant colonic tumour",
          "malignant neoplasm of colon",
          "malignant neoplasm of the colon",
          "malignant tumor of colon",
          "malignant tumor of the colon",
          "malignant tumour of colon",
          "malignant tumour of the colon"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0021063"
    },
    {
      "id": 21360,
      "label": "colorectal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7221,
        7738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080199",
          "EFO:1001951",
          "MEDGEN:3170",
          "NCIT:C2955",
          "UMLS:C0009402"
        ],
        "synonyms": [
          "cancer of large bowel",
          "cancer of large intestine",
          "cancer of the large bowel",
          "cancer of the large intestine",
          "colorectal (colon or rectal) cancer",
          "colorectal cancer",
          "large bowel cancer",
          "large intestine cancer",
          "CRC",
          "carcinoma of colorectum",
          "carcinoma of large bowel",
          "carcinoma of large intestine",
          "carcinoma of the large bowel",
          "carcinoma of the large intestine",
          "colorectal carcinoma",
          "colorectum carcinoma",
          "large bowel carcinoma",
          "large intestine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024331"
    },
    {
      "id": 21434,
      "label": "epithelial tumor of colon",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7078,
        7265
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "colon epithelial neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A epithelial neoplasm that involves the colon."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024479"
    }
  ],
  "children": [
    {
      "id": 4386,
      "label": "colon adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4179,
        6746
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:234",
          "EFO:1001949",
          "MEDGEN:137834",
          "NCIT:C4349",
          "ONCOTREE:COAD",
          "UMLS:C0338106",
          "icd11.foundation:773139368"
        ],
        "synonyms": [
          "adenocarcinoma - colon",
          "adenocarcinoma of colon",
          "adenocarcinoma of the colon",
          "colon adenocarcinoma",
          "colonic adenocarcinoma",
          "COAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the colon"
      },
      "child_count": 10,
      "reference_id": "MONDO:0002271"
    },
    {
      "id": 4512,
      "label": "rectosigmoid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4179,
        4513,
        23485
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2781",
          "MEDGEN:232963",
          "NCIT:C7421",
          "UMLS:C1327709",
          "icd11.foundation:1415734886"
        ],
        "synonyms": [
          "carcinoma of rectosigmoid junction",
          "rectosigmoid cancer",
          "rectosigmoid carcinoma",
          "rectosigmoid junction carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant epithelial neoplasm that arises from the rectosigmoid area and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. About 50% of colorectal carcinomas occur in the rectosigmoid area."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002424"
    },
    {
      "id": 5833,
      "label": "colon small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4179,
        4895
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6727",
          "GARD:0023759",
          "MEDGEN:232087",
          "NCIT:C6761",
          "UMLS:C1333099"
        ],
        "synonyms": [
          "Oat cell carcinoma of colon",
          "Oat cell carcinoma of the colon",
          "Oat cell colon carcinoma",
          "colon Oat cell carcinoma",
          "colon small cell carcinoma",
          "colon small cell neuroendocrine cancer",
          "colon small cell neuroendocrine carcinoma",
          "colonic Oat cell carcinoma",
          "colonic small cell carcinoma",
          "small cell carcinoma of colon",
          "small cell carcinoma of the colon",
          "small cell colon carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the colon. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003978"
    },
    {
      "id": 6447,
      "label": "colon carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4179,
        6478
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8826",
          "ICD10CM:D01.0",
          "ICD9:230.3",
          "MEDGEN:56334",
          "NCIT:C3638",
          "SCTID:92568009",
          "UMLS:C0154061",
          "icd11.foundation:1958429829"
        ],
        "synonyms": [
          "carcinoma in situ of colon",
          "carcinoma in situ of the colon",
          "colon cancer stage 0",
          "colon carcinoma in situ",
          "colon in situ carcinoma",
          "colonic carcinoma in situ",
          "stage 0 carcinoma of colon",
          "stage 0 carcinoma of the colon",
          "stage 0 colon cancer",
          "stage 0 colon cancer aJCC v6",
          "stage 0 colon cancer aJCC v6 and v7",
          "stage 0 colon cancer aJCC v7",
          "stage 0 colon carcinoma",
          "stage 0 colonic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the colon."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004663"
    },
    {
      "id": 7615,
      "label": "cecum carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4179,
        4180
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1519",
          "EFO:1000021",
          "MEDGEN:101762",
          "NCIT:C3491",
          "SCTID:255081007",
          "UMLS:C0149640"
        ],
        "synonyms": [
          "cecal cancer",
          "cecum cancer",
          "caecum carcinoma",
          "carcinoma of caecum",
          "carcinoma of cecum",
          "carcinoma of the cecum",
          "cecum carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the caecum"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006029"
    },
    {
      "id": 18544,
      "label": "squamous cell carcinoma of colon",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4179,
        7726
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5519",
          "GARD:0021768",
          "MEDGEN:272494",
          "NCIT:C5490",
          "Orphanet:423994",
          "SCTID:766981007",
          "UMLS:C1333100"
        ],
        "synonyms": [
          "colon epidermoid carcinoma",
          "colon squamous cell cancer",
          "colon squamous cell carcinoma",
          "colonic epidermoid carcinoma",
          "colonic squamous cell carcinoma",
          "epidermoid carcinoma of colon",
          "epidermoid carcinoma of the colon",
          "squamous cell carcinoma of colon",
          "squamous cell carcinoma of the colon",
          "squamous cell colon carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that involves the colon."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018513"
    }
  ],
  "roots": [
    {
      "id": 20304,
      "label": "malignant colon neoplasm"
    },
    {
      "id": 21360,
      "label": "colorectal carcinoma"
    },
    {
      "id": 21434,
      "label": "epithelial tumor of colon"
    }
  ]
}