{
  "id": 4184,
  "label": "pleural disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002037",
  "properties": {
    "xrefs": [
      "DOID:1532",
      "ICD9:518.89",
      "MEDGEN:10804",
      "MESH:D010995",
      "NCIT:C26859",
      "SCTID:88075009",
      "UMLS:C0032226"
    ],
    "synonyms": [
      "disease of pleura",
      "disease or disorder of pleura",
      "disorder of pleura",
      "pleura disease",
      "pleura disease or disorder",
      "pleural disorder",
      "pleural disorders",
      "non-neoplastic pleural disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050161",
          "EFO:0009433",
          "ICD9:478.1",
          "ICD9:478.19",
          "MEDGEN:712703",
          "SCTID:128272009",
          "UMLS:C1290325",
          "icd11.foundation:1582386590"
        ],
        "synonyms": [
          "disease of lower respiratory tract",
          "disease or disorder of lower respiratory tract",
          "disorder of lower respiratory tract",
          "lower respiratory tract disease",
          "lower respiratory tract disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the lower respiratory tract."
      },
      "child_count": 5,
      "reference_id": "MONDO:0000270"
    }
  ],
  "children": [
    {
      "id": 3253,
      "label": "pleurisy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4184,
        23249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10247",
          "EFO:1001825",
          "ICD10CM:R09.1",
          "ICD9:511.8",
          "MEDGEN:10807",
          "MESH:D010998",
          "NCIT:C26860",
          "SCTID:196075003",
          "UMLS:C0032231",
          "icd11.foundation:317852053"
        ],
        "synonyms": [
          "inflammation of pleura",
          "pleura inflammation",
          "pleuritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the pleura. It is usually caused by infections. Chest pain while breathing or coughing is the presenting symptom."
      },
      "child_count": 4,
      "reference_id": "MONDO:0000986"
    },
    {
      "id": 4219,
      "label": "pneumothorax",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4184
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1673",
          "HP:0002107",
          "ICD10WHO:J93",
          "ICD9:512.8",
          "MEDGEN:19365",
          "MESH:D011030",
          "NCIT:C38006",
          "SCTID:36118008",
          "UMLS:C0032326",
          "icd11.foundation:1946559257"
        ],
        "synonyms": [
          "pneumothorax",
          "pneumothorax (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Abnormal presence of air in the pleural cavity."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002076"
    },
    {
      "id": 12442,
      "label": "congenital chylothorax",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4184,
        17417
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060646",
          "GARD:0010156",
          "ICD9:511.89",
          "MEDGEN:87398",
          "MESH:C535461",
          "OMIM:603523",
          "Orphanet:264688",
          "SCTID:233646003",
          "UMLS:C0340014",
          "icd11.foundation:641475779"
        ],
        "synonyms": [
          "chylothorax, congenital",
          "hydrothorax, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Congenital chylothorax is a rare, potentially life-threatening neonatal condition characterized by the accumulation of chyle within the pleural space leading to respiratory distress, malnutrition and immunological compromise, either immediately after birth or within the first few weeks of life. Congenital chylothorax is the most common cause of pleural effusion in neonates; it can occur primarily due to developmental anomalies of the lymphatic duct or can be associated with chromosomal anomalies (e.g. Noonan syndrome, Turner syndrome and Down syndrome), hydrops fetalis, mediastinal neuroblastoma and other congenital malformations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011331"
    },
    {
      "id": 18658,
      "label": "pleural empyema",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4184
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3798",
          "EFO:0009680",
          "GARD:0021879",
          "HP:0011919",
          "MEDGEN:4928",
          "MESH:D016724",
          "Orphanet:449266",
          "SCTID:405950009",
          "UMLS:C0014013"
        ],
        "synonyms": [
          "pleural empyema",
          "pleural empyema (disease)",
          "abscess of thorax",
          "empyema",
          "purulent pleurisy",
          "purulent pleuritis",
          "pyothorax",
          "thorax abscess"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "The presence of pus in the thoracic cavity, between the visceral and parietal pleura."
      },
      "child_count": 1,
      "reference_id": "MONDO:0018667"
    },
    {
      "id": 20306,
      "label": "pleural neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4184,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:18523",
          "MESH:D010997",
          "NCIT:C3332",
          "ONCOTREE:PLEURA",
          "SCTID:126719004",
          "UMLS:C0032229"
        ],
        "synonyms": [
          "neoplasm of pleura",
          "neoplasm of pleural cavity",
          "neoplasm of the pleura",
          "pleura neoplasm",
          "pleura neoplasm (disease)",
          "pleura tumor",
          "pleura tumour",
          "pleural cavity neoplasm (disease)",
          "pleural cavity tumor",
          "pleural cavity tumour",
          "pleural neoplasm",
          "pleural tumor",
          "pleural tumour",
          "tumor of pleura",
          "tumor of the pleura",
          "tumour of pleura",
          "tumour of the pleura"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that involves the serous membrane that lines the lungs and thoracic cavity. Most pleural neoplasms are metastatic. Diffuse malignant mesothelioma is the most common primary malignant neoplasm of the pleura."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021065"
    }
  ],
  "roots": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder"
    }
  ]
}