{
  "id": 4199,
  "label": "lymphadenitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002052",
  "properties": {
    "xrefs": [
      "DOID:1602",
      "HP:0002840",
      "ICD9:289.1",
      "ICD9:683",
      "MEDGEN:7410",
      "MESH:D008199",
      "NCIT:C26821",
      "SCTID:41174002",
      "UMLS:C0024205",
      "icd11.foundation:1483611415"
    ],
    "synonyms": [
      "adenitis",
      "lymph node inflammation",
      "lymph nodeitis",
      "lymphadenitis",
      "lymphadenitis (disease)",
      "acute adenitis",
      "acute lymphadenitis",
      "chronic adenitis",
      "chronic lymphadenitis",
      "lymph gland infection"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Acute or chronic inflammation of one or more lymph nodes. It is usually caused by an infectious process."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6675,
      "label": "lymph node disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7447
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9942",
          "MEDGEN:78802",
          "NCIT:C35346",
          "SCTID:76616003",
          "UMLS:C0272394"
        ],
        "synonyms": [
          "disease of lymph node",
          "disease or disorder of lymph node",
          "disorder of lymph node",
          "lymph node disease",
          "lymph node disease or disorder",
          "lymph node disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Any disorder of the lymph nodes."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004928"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 3364,
      "label": "mesenteric lymphadenitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10782",
          "ICD10CM:I88.0",
          "ICD9:289.2",
          "MEDGEN:6318",
          "MESH:D008640",
          "NCIT:C26830",
          "SCTID:44897000",
          "UMLS:C0025469",
          "icd11.foundation:637335249"
        ],
        "synonyms": [
          "lymphadenitis (disease) of mesentery",
          "mesenteric adenitis",
          "mesenteric lymphadenitis",
          "mesentery lymphadenitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Inflammation of the mesenteric lymph nodes."
      },
      "child_count": 1,
      "reference_id": "MONDO:0001116"
    },
    {
      "id": 5056,
      "label": "cervical lymphadenitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4637",
          "MEDGEN:101763",
          "NCIT:C26937",
          "SCTID:3502005",
          "UMLS:C0149642"
        ],
        "synonyms": [
          "lymphadenitis (disease) of neck",
          "neck lymphadenitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Inflammation of the cervical lymph nodes."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003067"
    },
    {
      "id": 5057,
      "label": "postauricular lymphadenitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4638",
          "MEDGEN:183076",
          "NCIT:C27332",
          "UMLS:C0919638"
        ],
        "synonyms": [
          "lymphadenitis (disease) of mastoid lymph node",
          "mastoid lymph node lymphadenitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Inflammation of the postauricular lymph nodes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003068"
    },
    {
      "id": 5058,
      "label": "suppurative lymphadenitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4639",
          "ICD9:457.8",
          "MEDGEN:140258",
          "NCIT:C27135",
          "SCTID:48573006",
          "UMLS:C0392051",
          "icd11.foundation:1183198544"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A form of lymphadenitis that is characterized by formation of pus; it is most often caused by staphylococcal or streptococcal bacteria."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003069"
    },
    {
      "id": 5059,
      "label": "axillary lymphadenitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4640",
          "MEDGEN:182522",
          "NCIT:C27333",
          "UMLS:C0919797"
        ],
        "synonyms": [
          "axilla lymphadenitis (disease)",
          "axillary lymphadenitis",
          "lymphadenitis (disease) of axilla",
          "axillary adenitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An infection of the lymph nodes in the axilla."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003070"
    },
    {
      "id": 7323,
      "label": "cat-scratch disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199,
        7299
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11258",
          "EFO:0007195",
          "GARD:0000027",
          "ICD10CM:A28.1",
          "ICD9:078.3",
          "MEDGEN:2861",
          "MESH:D002372",
          "MedDRA:10007729",
          "NCIT:C84620",
          "Orphanet:50839",
          "SCTID:79974007",
          "UMLS:C0007361",
          "icd11.foundation:2003001085"
        ],
        "synonyms": [
          "Cat-scratch fever",
          "bartonellosis due to Bartonella henselae infection",
          "benign lymphoreticulosis",
          "Cat scratch disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Cat scratch disease is an infectious illness caused by the bacteria bartonella (Bartonella henselae). It is believed to be transmitted by cat scratches, bites, or exposure to cat saliva. This self-limiting infectious diseaseis characterized by a bump or blister at the site of the bite or scratch and swelling and pain in the lymph nodes. Other features may include fatigue, headache, achiness, and fever. Although cat-scratch disease usually subsides without treatment, antibiotic and/or antimicrobial therapy may help speed recovery."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005692"
    },
    {
      "id": 8394,
      "label": "sialadenitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3387,
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10303",
          "EFO:1001179",
          "ICD10CM:K11.2",
          "ICD9:527.2",
          "MEDGEN:48657",
          "MESH:D012793",
          "MedDRA:10040627",
          "NCIT:C115165",
          "NCIT:C26882",
          "SCTID:42982001",
          "UMLS:C0037023"
        ],
        "synonyms": [
          "lymphadenitis (disease) of saliva-secreting gland",
          "saliva-secreting gland lymphadenitis (disease)",
          "sialitis",
          "sialoadenitis",
          "adenitis, salivary gland",
          "salivary gland inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Sialadenitis is an infection of the salivary glands. It is usually caused by a virus or bacteria. The parotid (in front ofthe ear) and submandibular (under the chin) glands are most commonly affected. Sialadenitis may be associated with pain, tenderness, redness, and gradual, localized swelling of the affected area. Sialadenitis most commonly affects the elderly and chronically ill especially those with dry mouth or who are dehydrated, but can also affected people of any age including newborn babies. Diagnosis is usually made by clinical exam but a CT scan, MRI scan or ultrasound may be done if the doctor suspects an abscess or to look for stones. Treatment may include an antibiotic (if bacterial), warm compresses, increasing fluid intake and good oral hygiene. Most salivary gland infections go away on their own or are cured with treatment. Complications are not common."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006969"
    },
    {
      "id": 13767,
      "label": "Kawasaki disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199,
        18813
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13378",
          "EFO:0004246",
          "GARD:0006816",
          "ICD10CM:M30.3",
          "ICD9:446.1",
          "MEDGEN:10118",
          "MESH:D009080",
          "MedDRA:10023320",
          "NCIT:C34825",
          "OMIM:611775",
          "Orphanet:2331",
          "SCTID:75053002",
          "UMLS:C0026691",
          "icd11.foundation:540285662"
        ],
        "synonyms": [
          "Kawasaki syndrome",
          "acute febrile mucocutaneous lymph node syndrome",
          "acute febrile mucocutaneous lymph node syndrome [MCLS]",
          "infantile polyarteritis nodosa",
          "mucocutaneous lymph node syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A rare inflammatory disease characterized by an acute febrile, systemic, self-limiting, medium-vessel vasculitis primarily affecting children. It often causes acute coronary arteritis which is associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012727"
    },
    {
      "id": 18770,
      "label": "Kimura disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199,
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7365",
          "EFO:1000722",
          "GARD:0006835",
          "MEDGEN:46183",
          "MESH:D000082242",
          "MESH:D000796",
          "MedDRA:10048640",
          "NCIT:C26867",
          "Orphanet:482",
          "UMLS:C0033838",
          "Wikipedia:Kimura's_disease",
          "icd11.foundation:1229046951"
        ],
        "synonyms": [
          "Kimura's disease",
          "eosinophilic lymphogranuloma",
          "angiolymphoid hyperplasia with eosinophilia",
          "eosinophilic granuloma of soft tissue",
          "eosinophilic hyperplastic lymphogranuloma",
          "eosinophilic lymphofollicular granuloma",
          "eosinophilic lymphofolliculosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Kimura disease is a benign and chronic inflammatory disorder of unknown etiology, occurring mainly in Asian countries (very rarely in Western countries) and predominantly affecting young men, that usually presents with a solitary or multiple non-tender subcutaneous masses in the head and neck region (in particular the preauricular and submandibular area) and/or generalized painless lymphadenopathy, often with salivary gland involvement. Characteristic laboratory findings include blood eosinophilia and markedly elevated serum immunoglobulin E (IgE) levels. It is often associated with autoinflammatory disorders (i.e. ulcerative colitis, bronchial asthma) and a co-existing renal disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018830"
    },
    {
      "id": 18797,
      "label": "Kikuchi-Fujimoto disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006834",
          "MEDGEN:97979",
          "MESH:D020042",
          "NCIT:C71719",
          "Orphanet:50918",
          "SCTID:127217009",
          "UMLS:C0398367"
        ],
        "synonyms": [
          "Kikuchi disease",
          "histiocytic necrotizing lymphadenitis",
          "Kikuchi necrotizing lymphadenitis",
          "Kikuchi's disease",
          "Kikuchi-Fujimoto's disease",
          "histiocytic necrotising lymphadenitis",
          "nosocomial Kikuchi's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disorder, characterized by regional cervical lymphadenopathy with tenderness, usually accompanied with mild fever and night sweats. Less frequent symptoms include weight loss, nausea, vomiting, sore throat."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018864"
    }
  ],
  "roots": [
    {
      "id": 6675,
      "label": "lymph node disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}