{
  "id": 4216,
  "label": "malignant pineal area germ cell neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002073",
  "properties": {
    "xrefs": [
      "DOID:1660",
      "GARD:0012017",
      "ICD9:239.7",
      "MEDGEN:233159",
      "NCIT:C6767",
      "SCTID:277508009",
      "UMLS:C1334612"
    ],
    "synonyms": [
      "malignant germ cell neoplasm of pineal gland",
      "malignant germ cell neoplasm of pineal parenchyma",
      "malignant germ cell neoplasm of the pineal gland",
      "malignant germ cell neoplasm of the pineal parenchyma",
      "malignant germ cell tumor of pineal gland",
      "malignant germ cell tumor of pineal parenchyma",
      "malignant germ cell tumor of the pineal gland",
      "malignant germ cell tumor of the pineal parenchyma",
      "malignant germ cell tumour of pineal gland",
      "malignant germ cell tumour of pineal parenchyma",
      "malignant germ cell tumour of the pineal gland",
      "malignant germ cell tumour of the pineal parenchyma",
      "malignant pineal area germ cell tumor",
      "malignant pineal area germ cell tumour",
      "malignant pineal gland germ cell neoplasm",
      "malignant pineal gland germ cell tumor",
      "malignant pineal gland germ cell tumour",
      "malignant pineal parenchymal germ cell neoplasm",
      "malignant pineal parenchymal germ cell tumor",
      "malignant pineal parenchymal germ cell tumour",
      "malignant pineal region germ cell neoplasm",
      "malignant pineal region germ cell tumor",
      "malignant pineal region germ cell tumour",
      "pineal germ cell neoplasm, malignant",
      "pineal germ cell tumour",
      "pineal region germ cell tumour",
      "pineal cell tumor",
      "pineal cell tumour",
      "pineal region germinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant germ cell tumor that arises in the pineal region. Representative examples include germinoma, immature teratoma, choriocarcinoma, embryonal carcinoma and yolk sac tumor."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4999,
      "label": "central nervous system germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7694,
        18334
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4439",
          "GARD:0023321",
          "MEDGEN:232040",
          "NCIT:C5461",
          "UMLS:C1332880"
        ],
        "synonyms": [
          "CNS germ cell neoplasm",
          "CNS germ cell tumor",
          "CNS germ cell tumour",
          "central nervous system germ cell neoplasm",
          "central nervous system germ cell tumor",
          "central nervous system rare germ cell tumor",
          "central nervous system rare germ cell tumour",
          "germ cell neoplasm of CNS",
          "germ cell neoplasm of central nervous system",
          "germ cell neoplasm of the CNS",
          "germ cell neoplasm of the central nervous system",
          "germ cell tumor of CNS",
          "germ cell tumor of central nervous system",
          "germ cell tumor of the CNS",
          "germ cell tumor of the central nervous system",
          "germ cell tumour of CNS",
          "germ cell tumour of central nervous system",
          "germ cell tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A unique group of rare tumors of the central nervous system that affect mainly children and adolescents. Their morphologic and biologic profile corresponds to that of homologous germ cell tumors that arise in the gonads and in other extragonadal sites. Representative examples include: germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0003000"
    },
    {
      "id": 5094,
      "label": "extragonadal germ cell cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7832,
        18334
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4717",
          "GARD:0023371",
          "MEDGEN:235292",
          "NCIT:C8881",
          "UMLS:C1334581"
        ],
        "synonyms": [
          "extragonadal germ cell malignant tumour",
          "extragonadal germ cell tumor, malignant",
          "malignant extragonadal germ cell tumor",
          "malignant extragonadal germ cell tumour",
          "malignant neoplasm of extragonadal germ cell",
          "malignant neoplasm of the extragonadal germ cell",
          "malignant tumor of extragonadal germ cell",
          "malignant tumor of the extragonadal germ cell",
          "malignant tumour of extragonadal germ cell",
          "malignant tumour of the extragonadal germ cell",
          "tumour of extragonadal germ cell"
        ],
        "definition": "A malignant germ cell tumor that develops as a primary tumor in an anatomic site other than the testis or ovary."
      },
      "child_count": 18,
      "reference_id": "MONDO:0003113"
    },
    {
      "id": 5194,
      "label": "pineal gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5646,
        20310,
        20442
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5032",
          "GARD:0027637",
          "ICD10CM:C75.3",
          "ICD9:194.4",
          "MEDGEN:102284",
          "NCIT:C3573",
          "SCTID:363483004",
          "UMLS:C0153655"
        ],
        "synonyms": [
          "neoplasm of the pineal region",
          "pineocytic tumor",
          "pineocytic tumour",
          "tumor of the pineal region",
          "tumour of the pineal region",
          "cancer of pineal body",
          "malignant neoplasm of pineal body",
          "malignant neoplasm of pineal gland",
          "malignant neoplasm of the pineal gland",
          "malignant pineal area neoplasm",
          "malignant pineal area tumor",
          "malignant pineal area tumour",
          "malignant pineal body neoplasm",
          "malignant pineal gland neoplasm",
          "malignant pineal gland tumor",
          "malignant pineal gland tumour",
          "malignant pineal region neoplasm",
          "malignant pineal region tumor",
          "malignant pineal region tumour",
          "malignant tumor of pineal gland",
          "malignant tumor of the pineal gland",
          "malignant tumour of pineal gland",
          "malignant tumour of the pineal gland",
          "pineal body cancer",
          "pinealoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Abnormal malignant growth of the cells that comprise the pineal parenchyma."
      },
      "child_count": 9,
      "reference_id": "MONDO:0003249"
    }
  ],
  "children": [
    {
      "id": 5331,
      "label": "pineal region yolk sac tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        5333
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5341",
          "GARD:0023499",
          "MEDGEN:277518",
          "NCIT:C6752",
          "UMLS:C1335420"
        ],
        "synonyms": [
          "pineal body yolk sac tumor",
          "pineal body yolk sac tumour",
          "pineal region yolk Sac neoplasm",
          "pineal region yolk sac tumor",
          "endodermal sinus tumor of pineal region",
          "endodermal sinus tumor of the pineal region",
          "endodermal sinus tumour of pineal region",
          "endodermal sinus tumour of the pineal region",
          "pineal endodermal sinus neoplasm",
          "pineal endodermal sinus tumor",
          "pineal endodermal sinus tumour",
          "pineal region endodermal sinus neoplasm",
          "pineal region endodermal sinus tumor",
          "pineal region endodermal sinus tumour",
          "yolk Sac tumor of pineal region",
          "yolk Sac tumor of the pineal region",
          "yolk Sac tumour of pineal region",
          "yolk Sac tumour of the pineal region"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A yolk sac tumor that involves the pineal body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003399"
    },
    {
      "id": 5402,
      "label": "pineal region dysgerminoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        5001
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5510",
          "GARD:0023524",
          "MEDGEN:233328",
          "NCIT:C7169",
          "UMLS:C1335415"
        ],
        "synonyms": [
          "pineal body dysgerminoma (disease)",
          "pineal dysgerminoma",
          "pineal region dysgerminoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A dysgerminoma (disease) that involves the pineal body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003480"
    },
    {
      "id": 5423,
      "label": "pineal region choriocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        17190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5553",
          "GARD:0023538",
          "MEDGEN:233327",
          "NCIT:C6759",
          "UMLS:C1335414"
        ],
        "synonyms": [
          "choriocarcinoma of pineal area",
          "choriocarcinoma of pineal region",
          "choriocarcinoma of the pineal area",
          "choriocarcinoma of the pineal region",
          "pineal area choriocarcinoma",
          "pineal choriocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A choriocarcinoma (disease) that involves the pineal body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003509"
    },
    {
      "id": 5866,
      "label": "pineal region immature teratoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        5427,
        5475,
        5615,
        5864,
        21584
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6858",
          "GARD:0023779",
          "MEDGEN:277516",
          "NCIT:C6755",
          "UMLS:C1335416"
        ],
        "synonyms": [
          "atypical pineal teratoma",
          "immature teratoma of pineal area",
          "immature teratoma of pineal region",
          "immature teratoma of the pineal area",
          "immature teratoma of the pineal region",
          "pineal area immature teratoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004017"
    },
    {
      "id": 6038,
      "label": "pineal region germinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4216,
        4334
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7428",
          "GARD:0019162",
          "MEDGEN:208928",
          "NCIT:C8712",
          "Orphanet:91352",
          "UMLS:C0854912"
        ],
        "synonyms": [
          "germinoma",
          "pineal germinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A germinoma that arises from the pineal gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004216"
    }
  ],
  "roots": [
    {
      "id": 4999,
      "label": "central nervous system germ cell tumor"
    },
    {
      "id": 5094,
      "label": "extragonadal germ cell cancer"
    },
    {
      "id": 5194,
      "label": "pineal gland cancer"
    }
  ]
}