{
  "id": 4232,
  "label": "acanthoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002093",
  "properties": {
    "xrefs": [
      "DOID:174",
      "HP:0025432",
      "MEDGEN:208851",
      "MESH:D049309",
      "NCIT:C7419",
      "UMLS:C0846967"
    ],
    "synonyms": [
      "acanthoma",
      "acanthoma (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A benign skin neoplasm composed of epithelial cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 21573,
      "label": "benign epithelial skin neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20564,
        20690,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:83395",
          "NCIT:C7341",
          "UMLS:C0345981"
        ],
        "synonyms": [
          "benign epithelial skin neoplasm",
          "benign epithelial skin tumor",
          "benign epithelial skin tumour",
          "benign skin epithelium neoplasm",
          "benign skin epithelium tumor",
          "benign skin epithelium tumour",
          "epithelial skin neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A form of epithelial skin neoplasm without malignant characteristics."
      },
      "child_count": 24,
      "reference_id": "MONDO:0024666"
    }
  ],
  "children": [
    {
      "id": 4226,
      "label": "clear cell acanthoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:172",
          "MEDGEN:83098",
          "NCIT:C97041",
          "SCTID:254670002",
          "UMLS:C0333992",
          "icd11.foundation:1582724858"
        ],
        "synonyms": [
          "Degos acanthoma",
          "clear cell acanthoma (morphologic abnormality)",
          "pale (clear cell) acanthoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An acanthoma characterized by the presence of psoriasiform epidermal acanthosis and basal cells with pale cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002086"
    },
    {
      "id": 4966,
      "label": "large cell acanthoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4321",
          "MEDGEN:235249",
          "NCIT:C27518",
          "UMLS:C1334362"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002961"
    },
    {
      "id": 4967,
      "label": "epidermolytic acanthoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4323",
          "MEDGEN:272577",
          "NCIT:C27516",
          "UMLS:C1333414"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A benign epithelial verrucous lesion of the skin. Morphologically, it is characterized by the presence of epidermolytic hyperkeratosis and papillomatosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002962"
    },
    {
      "id": 4968,
      "label": "acantholytic acanthoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4324",
          "MEDGEN:220970",
          "NCIT:C27517",
          "UMLS:C1301270"
        ],
        "synonyms": [
          "acantholytic acanthoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A benign epithelial neoplasm of the skin. It presents as a papular or nodular lesion. Morphologically, it is characterized by the presence of hyperkeratosis, acanthosis, papillomatosis, and prominent acantholysis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002963"
    },
    {
      "id": 8343,
      "label": "pilar sheath acanthoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4322",
          "MEDGEN:83398",
          "NCIT:C4468",
          "SCTID:254693008",
          "UMLS:C0346005",
          "icd11.foundation:281473034"
        ],
        "synonyms": [
          "Infundibuloisthmicoma",
          "Pilar sheath acanthoma",
          "acanthoma of Pilar sheath",
          "acanthoma of the Pilar sheath"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A benign, small, papular or nodular skin neoplasm that usually arises above the upper lip. It is characterized by an epithelial proliferation with a central cavity. The cavity wall is lined with keratinocytes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006907"
    },
    {
      "id": 18969,
      "label": "warty dyskeratoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4232
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018899",
          "MEDGEN:137717",
          "MedDRA:10068856",
          "NCIT:C4087",
          "Orphanet:69745",
          "SCTID:254676008",
          "UMLS:C0334063",
          "icd11.foundation:1427186445"
        ],
        "synonyms": [
          "follicular dyskeratoma",
          "isolated follicular keratosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A rare, usually solitary, benign epithelial tumor of the skin that appears to arise from a hair follicle. It usually develops in the head and neck region as a nodular lesion with a central keratotic plug."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019077"
    }
  ],
  "roots": [
    {
      "id": 21573,
      "label": "benign epithelial skin neoplasm"
    }
  ]
}