{
  "id": 4233,
  "label": "vascular cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002095",
  "properties": {
    "xrefs": [
      "DOID:175",
      "MEDGEN:264315",
      "MESH:D009383",
      "NCIT:C8538",
      "Orphanet:673466",
      "UMLS:C1458139"
    ],
    "synonyms": [
      "Haemangiomatous tumor",
      "Haemangiomatous tumour",
      "blood vessel neoplasm",
      "blood vessel tumor",
      "blood vessel tumor (morphologic abnormality)",
      "blood vessel tumor disorder",
      "blood vessel tumors",
      "blood vessel tumors (morphologic abnormality)",
      "blood vessel tumour",
      "blood vessel tumour (morphologic abnormality)",
      "blood vessel tumour disorder",
      "blood vessel tumours",
      "blood vessel tumours (morphologic abnormality)",
      "neoplasm of great vessel",
      "vascular tumors",
      "vascular tumours",
      "cancer of vasculature",
      "malignant blood vessel neoplasm",
      "malignant blood vessel tumor",
      "malignant blood vessel tumour",
      "malignant neoplasm of vasculature",
      "malignant vascular tumor",
      "malignant vascular tumour",
      "malignant vasculature neoplasm",
      "pulmonary artery cancer",
      "vasculature cancer",
      "leiomyosarcoma of the renal vein",
      "malignant tumor of pulmonary artery",
      "malignant tumor of pulmonary vein",
      "malignant tumour of pulmonary artery",
      "malignant tumour of pulmonary vein",
      "malignant great vessel tumour",
      "renal vein leiomyosarcoma",
      "vascular tissue neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A malignant neoplasm arising from the blood vessels."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4237,
      "label": "cardiovascular cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        21585
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:176",
          "MEDGEN:858066",
          "NCIT:C114940",
          "UMLS:C3898472"
        ],
        "synonyms": [
          "cardiovascular neoplasm",
          "cancer of cardiovascular system",
          "cardiovascular system cancer",
          "cardiovascular tumours",
          "malignant cardiovascular neoplasm",
          "malignant cardiovascular system neoplasm",
          "malignant neoplasm of cardiovascular system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the cardiovascular system."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002100"
    },
    {
      "id": 20321,
      "label": "blood vessel neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1651181",
          "NCIT:C7387",
          "SCTID:126736007",
          "UMLS:C4722524"
        ],
        "synonyms": [
          "blood vessel neoplasm",
          "blood vessel neoplasm (disease)",
          "blood vessel tumor",
          "blood vessel tumour",
          "neoplasm of blood vessel",
          "tumor of blood vessel",
          "tumour of blood vessel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A neoplasm arising from arteries or veins."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021080"
    }
  ],
  "children": [
    {
      "id": 4728,
      "label": "choroid plexus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4729,
        17175,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3540",
          "EFO:0007206",
          "GARD:0023212",
          "MEDGEN:138053",
          "NCIT:C4533",
          "UMLS:C0346289"
        ],
        "synonyms": [
          "choroid plexus neoplasm",
          "tumor of choroid plexus",
          "tumour of choroid plexus",
          "tumour of the choroid plexus",
          "cancer of choroid plexus",
          "choroid plexus cancer",
          "malignant choroid plexus neoplasm",
          "malignant choroid plexus neoplasms",
          "malignant choroid plexus tumor",
          "malignant choroid plexus tumors",
          "malignant choroid plexus tumour",
          "malignant choroid plexus tumours",
          "malignant neoplasm of choroid plexus",
          "malignant neoplasm of the choroid plexus",
          "malignant tumor of choroid plexus",
          "malignant tumor of the choroid plexus",
          "malignant tumour of choroid plexus",
          "malignant tumour of the choroid plexus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the choroid plexus"
      },
      "child_count": 8,
      "reference_id": "MONDO:0002681"
    },
    {
      "id": 7833,
      "label": "malignant jugulotympanic paraganglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4233,
        4265,
        4753,
        6420,
        20305,
        20310,
        20329,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024363",
          "MEDGEN:87584",
          "NCIT:C4623",
          "UMLS:C0347856"
        ],
        "synonyms": [
          "cancer of jugular body",
          "jugular body cancer",
          "malignant glomus jugulare neoplasm",
          "malignant glomus jugulare tumor",
          "malignant glomus jugulare tumour",
          "malignant jugular body neoplasm",
          "malignant jugulotympanic paraganglioma",
          "malignant neoplasm of glomus jugulare",
          "malignant neoplasm of jugular body",
          "malignant neoplasm of the glomus jugulare",
          "malignant tumor of glomus jugulare",
          "malignant tumor of the glomus jugulare",
          "malignant tumour of glomus jugulare",
          "malignant tumour of the glomus jugulare"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A jugulotympanic paraganglioma that metastasizes to other anatomic sites."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006291"
    },
    {
      "id": 8111,
      "label": "adrenal cortex carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4840,
        6814,
        20494
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3948",
          "DOID:3959",
          "DOID:660",
          "EFO:1000796",
          "GARD:0000558",
          "HP:0006744",
          "ICDO:8370/3",
          "MEDGEN:104917",
          "MedDRA:10001388",
          "NANDO:2200073",
          "NCIT:C9325",
          "NORD:733",
          "ONCOTREE:ACC",
          "Orphanet:1501",
          "SCTID:255035007",
          "UMLS:C0206686",
          "icd11.foundation:114092945"
        ],
        "synonyms": [
          "adrenal cortex cancer",
          "adrenal cortical tumors",
          "adrenal cortical tumours",
          "adrenocortical cancer",
          "cancer of the adrenal cortex",
          "malignant adrenocortical tumor",
          "malignant adrenocortical tumour",
          "malignant neoplasm of adrenal cortex",
          "malignant tumor of adrenal cortex",
          "malignant tumour of adrenal cortex",
          "ACC",
          "Adenoid Cystic Carcinoma",
          "adenocarcinoma, adrenocortical, malignant",
          "adrenal cortex adenocarcinoma",
          "adrenal cortex carcinoma",
          "adrenal cortical adenocarcinoma",
          "adrenal cortical carcinoma",
          "adrenal cortical carcinoma (morphologic abnormality)",
          "adrenocortical carcinoma",
          "adrenocortical carcinoma (disease)",
          "carcinoma of adrenal cortex",
          "carcinoma of the adrenal cortex",
          "carcinoma, adrenocortical, malignant",
          "cortical cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006639"
    },
    {
      "id": 8163,
      "label": "choroid cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4710,
        20462,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12759",
          "ICD10CM:C69.3",
          "ICD9:190.6",
          "MEDGEN:57794",
          "MESH:D002830",
          "MedDRA:10057405",
          "NCIT:C3566",
          "SCTID:363466008",
          "UMLS:C0153630"
        ],
        "synonyms": [
          "choroid neoplasm",
          "choroidal tumor",
          "choroidal tumour",
          "cancer of optic choroid",
          "malignant choroid neoplasm",
          "malignant choroid tumor",
          "malignant choroid tumour",
          "malignant neoplasm of choroid",
          "malignant neoplasm of optic choroid",
          "malignant neoplasm of the choroid",
          "malignant optic choroid neoplasm",
          "malignant tumor of choroid",
          "malignant tumor of the choroid",
          "malignant tumour of choroid",
          "malignant tumour of the choroid",
          "optic choroid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A malignant neoplasm involving the optic choroid."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006700"
    },
    {
      "id": 16338,
      "label": "epithelioid hemangioendothelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4233,
        20360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080190",
          "GARD:0020014",
          "ICDO:9130/3",
          "ICDO:9133/1",
          "ICDO:9133/3",
          "MEDGEN:569676",
          "MESH:D018323",
          "NCIT:C3800",
          "NORD:124536",
          "ONCOTREE:EHAE",
          "Orphanet:157791",
          "SCTID:403981003",
          "SCTID:54124005",
          "UMLS:C0334538"
        ],
        "synonyms": [
          "epithelioid angioendothelioma",
          "epithelioid angiosarcoma",
          "epithelioid hemangioendothelioma",
          "malignant epithelioid hemangioendothelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A low-grade malignant blood vessel neoplasm. It is characterized by the presence of epithelioid endothelial cells. The neoplastic cells are arranged in cords and nests, which are embedded in a myxoid to hyalinized stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015523"
    },
    {
      "id": 17394,
      "label": "angiosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0001816",
          "EFO:0003968",
          "GARD:0020900",
          "HP:0200058",
          "ICD9:171.9",
          "ICDO:9120/3",
          "MEDGEN:42385",
          "MESH:D006394",
          "MedDRA:10002476",
          "NCIT:C3088",
          "ONCOTREE:ANGS",
          "Orphanet:263413",
          "SCTID:403977003",
          "UMLS:C0018923"
        ],
        "synonyms": [
          "angiosarcoma",
          "angiosarcoma (disease)",
          "blood vessel sarcoma",
          "hemangiosarcoma",
          "hemangiosarcoma, malignant",
          "malignant angioendothelioma",
          "malignant hemangioendothelioma",
          "sarcoma of blood vessel",
          "vascular sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma."
      },
      "child_count": 38,
      "reference_id": "MONDO:0016982"
    },
    {
      "id": 23003,
      "label": "great vessel cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:777096",
          "NCIT:C4575",
          "UMLS:C3665405"
        ],
        "synonyms": [
          "cancer of great vessel of heart",
          "great vessel cancer",
          "great vessel of heart cancer",
          "malignant great vessel neoplasm",
          "malignant great vessel of heart neoplasm",
          "malignant great vessel tumor",
          "malignant great vessel tumour",
          "malignant neoplasm of great vessel of heart"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant neoplasm arising from the great vessels."
      },
      "child_count": 5,
      "reference_id": "MONDO:0040676"
    }
  ],
  "roots": [
    {
      "id": 4237,
      "label": "cardiovascular cancer"
    },
    {
      "id": 20321,
      "label": "blood vessel neoplasm"
    }
  ]
}