{
  "id": 4249,
  "label": "peritoneal carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002113",
  "properties": {
    "xrefs": [
      "DOID:1791",
      "MEDGEN:756216",
      "SCTID:447781009",
      "UMLS:C3163804"
    ],
    "synonyms": [
      "carcinoma of peritoneum",
      "peritoneum carcinoma",
      "primary peritoneal carcinoma"
    ],
    "definition": "A peritoneum cancer that is located in the inside of the abdomen."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4227,
      "label": "peritoneum cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        8339
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1725",
          "ICD9:158.8",
          "ICD9:158.9",
          "ICD9:159.8",
          "MEDGEN:102270",
          "NCIT:C3538",
          "SCTID:363492001",
          "UMLS:C0153467",
          "icd11.foundation:315445782"
        ],
        "synonyms": [
          "cancer of peritoneum",
          "cancer of the peritoneum",
          "malignant neoplasm of peritoneum",
          "malignant peritoneal neoplasm",
          "malignant peritoneum neoplasm",
          "peritoneal cancer",
          "peritoneal cavity cancer",
          "peritoneum cancer"
        ],
        "definition": "A malignant neoplasm involving the peritoneum"
      },
      "child_count": 12,
      "reference_id": "MONDO:0002087"
    },
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 5154,
      "label": "peritoneal serous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4249,
        6974
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4901"
        ],
        "synonyms": [
          "peritoneum serous adenocarcinoma",
          "primary peritoneal serous adenocarcinoma"
        ],
        "definition": "A rare, serous adenocarcinoma that arises from the lining of the peritoneum. It affects females. The clinical behavior and pathologic characteristics are similar to the serous adenocarcinoma that arises from the ovary."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003195"
    },
    {
      "id": 16451,
      "label": "primary peritoneal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020103",
          "HP:0030406",
          "MEDGEN:269516",
          "NCIT:C40022",
          "Orphanet:168829",
          "UMLS:C1514428"
        ],
        "synonyms": [
          "EOPPC",
          "Extra-ovarian primary peritoneal carcinoma",
          "PPC",
          "primary peritoneal cancer",
          "primary peritoneal carcinoma",
          "primary peritoneal carcinoma (disease)",
          "primary peritoneal serous carcinoma",
          "serous surface papillary carcinoma"
        ],
        "definition": "A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement."
      },
      "child_count": 1,
      "reference_id": "MONDO:0015686"
    },
    {
      "id": 17431,
      "label": "pseudomyxoma peritonei",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4249,
        18424,
        24710
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3559",
          "GARD:0007488",
          "ICDO:8480/6",
          "MEDGEN:18726",
          "MESH:D011553",
          "MedDRA:10037138",
          "NCIT:C3345",
          "NORD:1628",
          "Orphanet:26790",
          "SCTID:307601000",
          "UMLS:C0033822",
          "icd11.foundation:1849365560"
        ],
        "synonyms": [
          "Adenomucinosis",
          "Myxoma peritonei",
          "PMP",
          "gelatinous ascites",
          "mucinous ascites",
          "peritoneal cavity pseudomyxoma peritonei",
          "pseudomyxoma peritonei",
          "pseudomyxoma peritonei (morphologic abnormality)",
          "well differentiated peritoneal mucinous adenocarcinoma",
          "syndrome of pseudomyxoma peritonei"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Pseudomyxoma peritonei is characterized by disseminated intra-peritoneal mucinous tumors and mucinous ascites in the abdomen and pelvis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017048"
    }
  ],
  "roots": [
    {
      "id": 4227,
      "label": "peritoneum cancer"
    },
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}